The effect of rifampicin on darunavir, ritonavir, and dolutegravir exposure within peripheral blood mononuclear cells: a dose escalation study. De Nicolò, A., Calcagno, A., Motta, I., Vivo, E. D., D'Avolio, A., Perri, G. D., Wiesner, L., Ebrahim, I., Maartens, G., Orrell, C., & McIlleron, H. Antimicrobial Agents and Chemotherapy, 66(6):e0013622, American Society for Microbiology 1752 N St., N.W., Washington, DC, may, 2022. Paper doi abstract bibtex Ritonavir-boosted darunavir (DRV/r) and dolutegravir (DTG) are affected by induction of metabolizing enzymes and efflux transporters caused by rifampicin (RIF). This complicates the treatment of pe...
@article{Nicolo2022,
abstract = {Ritonavir-boosted darunavir (DRV/r) and dolutegravir (DTG) are affected by induction of metabolizing enzymes and efflux transporters caused by rifampicin (RIF). This complicates the treatment of pe...},
author = {{De Nicol{\`{o}}}, Amedeo and Calcagno, Andrea and Motta, Ilaria and Vivo, Elisa De and D'Avolio, Antonio and Perri, Giovanni Di and Wiesner, Lubbe and Ebrahim, Isma-eel and Maartens, Gary and Orrell, Catherine and McIlleron, Helen},
doi = {10.1128/AAC.00136-22},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/De Nicol{\`{o}} et al. - 2022 - The effect of rifampicin on darunavir, ritonavir, and dolutegravir exposure within peripheral blood mononuclea.pdf:pdf},
issn = {0066-4804},
journal = {Antimicrobial Agents and Chemotherapy},
keywords = {OA,PBMC,darunavir,dolutegravir,drug interactions,drug-drug interaction,fund{\_}not{\_}ack,original,pharmacokinetics,rifampicin},
mendeley-tags = {OA,fund{\_}not{\_}ack,original},
month = {may},
number = {6},
pages = {e0013622},
pmid = {35583344},
publisher = {American Society for Microbiology 1752 N St., N.W., Washington, DC},
title = {{The effect of rifampicin on darunavir, ritonavir, and dolutegravir exposure within peripheral blood mononuclear cells: a dose escalation study}},
url = {https://journals.asm.org/doi/full/10.1128/aac.00136-22},
volume = {66},
year = {2022}
}
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