Transplacental transfer of polychlorinated biphenyls and polybrominated diphenyl ethers in arctic beluga whales (Delphinapterus leucas). Desforges, J. W, Ross, P. S, & Loseto, L. L Environmental toxicology and chemistry / SETAC, 31(2):296–300, February, 2012. ![Transplacental transfer of polychlorinated biphenyls and polybrominated diphenyl ethers in arctic beluga whales (Delphinapterus leucas). [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex This study found that arctic beluga whales (Delphinapterus leucas) transferred, on average, 11.4% (7.5 mg) and 11.1% (0.1 mg) of their polychlorinated biphenyl (PCB) and polybrominated diphenyl ether (PBDE) blubber burden to their near-term fetuses. A single physicochemical parameter, log K(OW), largely explained this transplacental transfer for PCBs (r(2) =0.79, p \textless 0.00001) and PBDEs (r(2) = 0.37, p = 0.007), with congeners having a log K(OW) \textless 6.5 preferentially transferred to the fetus. Blubber concentrations of 257 ng/g lipid weight (lw) PCBs and 3.8 ng/g (lw) PBDEs in beluga fetuses highlights the exposure to endocrine-disrupting compounds during a critical developmental stage. The implications of detecting these levels of legacy PCBs and the flame retardant PBDEs in unborn arctic beluga are unclear.
@article{desforges_transplacental_2012,
title = {Transplacental transfer of polychlorinated biphenyls and polybrominated diphenyl ethers in arctic beluga whales ({Delphinapterus} leucas).},
volume = {31},
issn = {1552-8618},
url = {http://www.ncbi.nlm.nih.gov/pubmed/22095624},
doi = {10.1002/etc.750},
abstract = {This study found that arctic beluga whales (Delphinapterus leucas) transferred, on average, 11.4\% (7.5 mg) and 11.1\% (0.1 mg) of their polychlorinated biphenyl (PCB) and polybrominated diphenyl ether (PBDE) blubber burden to their near-term fetuses. A single physicochemical parameter, log K(OW), largely explained this transplacental transfer for PCBs (r(2) =0.79, p {\textbackslash}textless 0.00001) and PBDEs (r(2) = 0.37, p = 0.007), with congeners having a log K(OW) {\textbackslash}textless 6.5 preferentially transferred to the fetus. Blubber concentrations of 257 ng/g lipid weight (lw) PCBs and 3.8 ng/g (lw) PBDEs in beluga fetuses highlights the exposure to endocrine-disrupting compounds during a critical developmental stage. The implications of detecting these levels of legacy PCBs and the flame retardant PBDEs in unborn arctic beluga are unclear.},
number = {2},
journal = {Environmental toxicology and chemistry / SETAC},
author = {Desforges, Jean-Pierre W and Ross, Peter S and Loseto, Lisa L},
month = feb,
year = {2012},
pmid = {22095624},
keywords = {Adipose Tissue, Adipose Tissue: metabolism, Animals, Arctic Regions, Beluga Whale, Beluga Whale: metabolism, Chemical, Chemical: metabolism, Endocrine Disruptors, Endocrine Disruptors: metabolism, Environmental Monitoring, Female, Flame Retardants: metabolism, Flame retardants, Halogenated Diphenyl Ethers, Halogenated Diphenyl Ethers: metabolism, Maternal Exposure, Maternal-Fetal Exchange, Polychlorinated Biphenyls, Polychlorinated Biphenyls: metabolism, Pregnancy, Water Pollutants},
pages = {296--300},
}
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A single physicochemical parameter, log K(OW), largely explained this transplacental transfer for PCBs (r(2) =0.79, p \\textless 0.00001) and PBDEs (r(2) = 0.37, p = 0.007), with congeners having a log K(OW) \\textless 6.5 preferentially transferred to the fetus. Blubber concentrations of 257 ng/g lipid weight (lw) PCBs and 3.8 ng/g (lw) PBDEs in beluga fetuses highlights the exposure to endocrine-disrupting compounds during a critical developmental stage. 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A single physicochemical parameter, log K(OW), largely explained this transplacental transfer for PCBs (r(2) =0.79, p {\\textbackslash}textless 0.00001) and PBDEs (r(2) = 0.37, p = 0.007), with congeners having a log K(OW) {\\textbackslash}textless 6.5 preferentially transferred to the fetus. Blubber concentrations of 257 ng/g lipid weight (lw) PCBs and 3.8 ng/g (lw) PBDEs in beluga fetuses highlights the exposure to endocrine-disrupting compounds during a critical developmental stage. The implications of detecting these levels of legacy PCBs and the flame retardant PBDEs in unborn arctic beluga are unclear.},\n\tnumber = {2},\n\tjournal = {Environmental toxicology and chemistry / SETAC},\n\tauthor = {Desforges, Jean-Pierre W and Ross, Peter S and Loseto, Lisa L},\n\tmonth = feb,\n\tyear = {2012},\n\tpmid = {22095624},\n\tkeywords = {Adipose Tissue, Adipose Tissue: metabolism, Animals, Arctic Regions, Beluga Whale, Beluga Whale: metabolism, Chemical, Chemical: metabolism, Endocrine Disruptors, Endocrine Disruptors: metabolism, Environmental Monitoring, Female, Flame Retardants: metabolism, Flame retardants, Halogenated Diphenyl Ethers, Halogenated Diphenyl Ethers: metabolism, Maternal Exposure, Maternal-Fetal Exchange, Polychlorinated Biphenyls, Polychlorinated Biphenyls: metabolism, Pregnancy, Water Pollutants},\n\tpages = {296--300},\n}\n\n\n\n","author_short":["Desforges, J. W","Ross, P. S","Loseto, L. 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