Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current. Desplantez, T., McCain, M., L., Beauchamp, P., Rigoli, G., Rothen-Rutishauser, B., Parker, K., K., & Kleber, A., G. Cardiovascular research, 94(1):58-65, 4, 2012.
Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current. [link]Website  abstract   bibtex   
Remodelling and regional gradients in expression of connexins (Cx) are thought to contribute to atrial electrical dysfunction and atrial fibrillation. We assessed the effect of interaction between Cx43, Cx40, and Cx45 on atrial cell-to-cell coupling and inward Na current (I(Na)) in engineered pairs of atrial myocytes derived from wild-type mice (Cx43(+/+)) and mice with genetic ablation of Cx43 (Cx43(-/-)).
@article{
 title = {Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current.},
 type = {article},
 year = {2012},
 identifiers = {[object Object]},
 pages = {58-65},
 volume = {94},
 websites = {http://cardiovascres.oxfordjournals.org/cgi/content/abstract/cvs025v1},
 month = {4},
 day = {1},
 id = {d0100c1e-5e4c-3eb7-bab0-2c70afdcdda5},
 created = {2012-09-16T13:41:27.000Z},
 accessed = {2012-07-16},
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 last_modified = {2017-03-15T18:44:14.327Z},
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 abstract = {Remodelling and regional gradients in expression of connexins (Cx) are thought to contribute to atrial electrical dysfunction and atrial fibrillation. We assessed the effect of interaction between Cx43, Cx40, and Cx45 on atrial cell-to-cell coupling and inward Na current (I(Na)) in engineered pairs of atrial myocytes derived from wild-type mice (Cx43(+/+)) and mice with genetic ablation of Cx43 (Cx43(-/-)).},
 bibtype = {article},
 author = {Desplantez, Thomas and McCain, Megan L and Beauchamp, Philippe and Rigoli, Ghislaine and Rothen-Rutishauser, Barbara and Parker, Kevin Kit and Kleber, Andre G},
 journal = {Cardiovascular research},
 number = {1}
}

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