@article{dharmasiri_axr4_2006,
	title = {{AXR4} is required for localization of the auxin influx facilitator {AUX1}},
	volume = {312},
	issn = {0036-8075},
	doi = {10/djwj2k},
	abstract = {The AUX1 and PIN auxin influx and efflux facilitators are key regulators of root growth and development. For root gravitropism to occur, AUX1 and PIN2 must transport auxin via the lateral root cap to elongating epidermal cells. Genetic studies suggest that AXR4 functions in the same pathway as AUX1. Here we show that AXR4 is a previously unidentified accessory protein of the endoplasmic reticulum (ER) that regulates localization of AUX1 but not of PIN proteins. Loss of AXR4 resulted in abnormal accumulation of AUX1 in the ER of epidermal cells, indicating that the axr4 agravitropic phenotype is caused by defective AUX1 trafficking in the root epidermis.},
	language = {English},
	number = {5777},
	journal = {Science},
	publisher = {Amer Assoc Advancement Science},
	author = {Dharmasiri, S. and Swarup, R. and Mockaitis, K. and Dharmasiri, N. and Singh, S. K. and Kowalchyk, M. and Marchant, A. and Mills, S. and Sandberg, G. and Bennett, M. J. and Estelle, M.},
	month = may,
	year = {2006},
	note = {Place: Washington
WOS:000237957400055},
	keywords = {arabidopsis, growth, mechanism, pathways, permease aux1, proteins, resistant mutants, root gravitropism, transport},
	pages = {1218--1220},
}

{"_id":"3QLrvqpgvrTSwhQ9j","bibbaseid":"dharmasiri-swarup-mockaitis-dharmasiri-singh-kowalchyk-marchant-mills-etal-axr4isrequiredforlocalizationoftheauxininfluxfacilitatoraux1-2006","author_short":["Dharmasiri, S.","Swarup, R.","Mockaitis, K.","Dharmasiri, N.","Singh, S. K.","Kowalchyk, M.","Marchant, A.","Mills, S.","Sandberg, G.","Bennett, M. J.","Estelle, M."],"bibdata":{"bibtype":"article","type":"article","title":"AXR4 is required for localization of the auxin influx facilitator AUX1","volume":"312","issn":"0036-8075","doi":"10/djwj2k","abstract":"The AUX1 and PIN auxin influx and efflux facilitators are key regulators of root growth and development. For root gravitropism to occur, AUX1 and PIN2 must transport auxin via the lateral root cap to elongating epidermal cells. Genetic studies suggest that AXR4 functions in the same pathway as AUX1. Here we show that AXR4 is a previously unidentified accessory protein of the endoplasmic reticulum (ER) that regulates localization of AUX1 but not of PIN proteins. Loss of AXR4 resulted in abnormal accumulation of AUX1 in the ER of epidermal cells, indicating that the axr4 agravitropic phenotype is caused by defective AUX1 trafficking in the root epidermis.","language":"English","number":"5777","journal":"Science","publisher":"Amer Assoc Advancement Science","author":[{"propositions":[],"lastnames":["Dharmasiri"],"firstnames":["S."],"suffixes":[]},{"propositions":[],"lastnames":["Swarup"],"firstnames":["R."],"suffixes":[]},{"propositions":[],"lastnames":["Mockaitis"],"firstnames":["K."],"suffixes":[]},{"propositions":[],"lastnames":["Dharmasiri"],"firstnames":["N."],"suffixes":[]},{"propositions":[],"lastnames":["Singh"],"firstnames":["S.","K."],"suffixes":[]},{"propositions":[],"lastnames":["Kowalchyk"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Marchant"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Mills"],"firstnames":["S."],"suffixes":[]},{"propositions":[],"lastnames":["Sandberg"],"firstnames":["G."],"suffixes":[]},{"propositions":[],"lastnames":["Bennett"],"firstnames":["M.","J."],"suffixes":[]},{"propositions":[],"lastnames":["Estelle"],"firstnames":["M."],"suffixes":[]}],"month":"May","year":"2006","note":"Place: Washington WOS:000237957400055","keywords":"arabidopsis, growth, mechanism, pathways, permease aux1, proteins, resistant mutants, root gravitropism, transport","pages":"1218–1220","bibtex":"@article{dharmasiri_axr4_2006,\n\ttitle = {{AXR4} is required for localization of the auxin influx facilitator {AUX1}},\n\tvolume = {312},\n\tissn = {0036-8075},\n\tdoi = {10/djwj2k},\n\tabstract = {The AUX1 and PIN auxin influx and efflux facilitators are key regulators of root growth and development. For root gravitropism to occur, AUX1 and PIN2 must transport auxin via the lateral root cap to elongating epidermal cells. Genetic studies suggest that AXR4 functions in the same pathway as AUX1. Here we show that AXR4 is a previously unidentified accessory protein of the endoplasmic reticulum (ER) that regulates localization of AUX1 but not of PIN proteins. Loss of AXR4 resulted in abnormal accumulation of AUX1 in the ER of epidermal cells, indicating that the axr4 agravitropic phenotype is caused by defective AUX1 trafficking in the root epidermis.},\n\tlanguage = {English},\n\tnumber = {5777},\n\tjournal = {Science},\n\tpublisher = {Amer Assoc Advancement Science},\n\tauthor = {Dharmasiri, S. and Swarup, R. and Mockaitis, K. and Dharmasiri, N. and Singh, S. K. and Kowalchyk, M. and Marchant, A. and Mills, S. and Sandberg, G. and Bennett, M. J. and Estelle, M.},\n\tmonth = may,\n\tyear = {2006},\n\tnote = {Place: Washington\nWOS:000237957400055},\n\tkeywords = {arabidopsis, growth, mechanism, pathways, permease aux1, proteins, resistant mutants, root gravitropism, transport},\n\tpages = {1218--1220},\n}\n\n\n\n","author_short":["Dharmasiri, S.","Swarup, R.","Mockaitis, K.","Dharmasiri, N.","Singh, S. K.","Kowalchyk, M.","Marchant, A.","Mills, S.","Sandberg, G.","Bennett, M. J.","Estelle, M."],"key":"dharmasiri_axr4_2006","id":"dharmasiri_axr4_2006","bibbaseid":"dharmasiri-swarup-mockaitis-dharmasiri-singh-kowalchyk-marchant-mills-etal-axr4isrequiredforlocalizationoftheauxininfluxfacilitatoraux1-2006","role":"author","urls":{},"keyword":["arabidopsis","growth","mechanism","pathways","permease aux1","proteins","resistant mutants","root gravitropism","transport"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/zotero/upscpub","dataSources":["fvfkWcShg3Mybjoog","Tu3jPdZyJF3j547xT","9cGcv2t8pRzC92kzs","3zTPPmKj8BiTcpc6C"],"keywords":["arabidopsis","growth","mechanism","pathways","permease aux1","proteins","resistant mutants","root gravitropism","transport"],"search_terms":["axr4","required","localization","auxin","influx","facilitator","aux1","dharmasiri","swarup","mockaitis","dharmasiri","singh","kowalchyk","marchant","mills","sandberg","bennett","estelle"],"title":"AXR4 is required for localization of the auxin influx facilitator AUX1","year":2006}