Psychiatric comorbidities associated with a positive screening using the Montreal Cognitive Assessment (MoCA) test in subjects with severe alcohol use disorder

Psychiatric comorbidities associated with a positive screening using the Montreal Cognitive Assessment (MoCA) test in subjects with severe alcohol use disorder. D'Hondt, F., Lescut, C., Maurage, P., Menard, O., Gibour, B., Cottencin, O., Montègue, S., Jardri, R., & Rolland, B. Drug and Alcohol Dependence, 191(May):266–269, Elsevier, D'Hondt, Fabien, Unite CURE, Secretariat de Psychiatrie de l'enfant et de l'Adolescent, Hopital Fontan 1, CHU de Lille, CS 70001, 59037, Lille, France, Cedex, oct, 2018.

Paper doi abstract bibtex

Background: Patients with severe alcohol use disorder (SAUD) frequently show cognitive deficits that can be efficiently identified using screening tools such as the Montreal Cognitive Assessment (MoCA) test. These cognitive deficits, which reduce the efficacy of therapeutic interventions and may contribute to dropout and relapse, could be, however, partly due to a treatable other cause. Accordingly, this exploratory study examined whether psychiatric comorbid disorders can induce a positive MoCA screening among recently detoxified SAUD subjects. Methods: One hundred recently detoxified patients with SAUD were divided into two groups according to whether they presented cognitive deficits using the MoCA. Groups were compared for demographic data, SAUD severity, impulsivity, and psychiatric comorbidities. The significant parameters were then introduced in a logistic regression model to establish their relative contributions in a positive MoCA status in SAUD subjects. Results: Among the significant parameters revealed by the bivariable analyses, agoraphobia and current depressive episode were found to be significant predictors of the MoCA status in the multivariable comparisons. Conclusions: A positive MoCA screening for cognitive impairments among post-detoxification SAUD patients could also be related to comorbid agoraphobia and depressive episode rather than to SAUD itself. A comprehensive psychiatric assessment must be performed in SAUD patients so that other potential causes of cognitive deficits, in particular with regard to mood and anxiety disorders, can be identified and treated.

@article{DHondt2018,
abstract = {Background: Patients with severe alcohol use disorder (SAUD) frequently show cognitive deficits that can be efficiently identified using screening tools such as the Montreal Cognitive Assessment (MoCA) test. These cognitive deficits, which reduce the efficacy of therapeutic interventions and may contribute to dropout and relapse, could be, however, partly due to a treatable other cause. Accordingly, this exploratory study examined whether psychiatric comorbid disorders can induce a positive MoCA screening among recently detoxified SAUD subjects. Methods: One hundred recently detoxified patients with SAUD were divided into two groups according to whether they presented cognitive deficits using the MoCA. Groups were compared for demographic data, SAUD severity, impulsivity, and psychiatric comorbidities. The significant parameters were then introduced in a logistic regression model to establish their relative contributions in a positive MoCA status in SAUD subjects. Results: Among the significant parameters revealed by the bivariable analyses, agoraphobia and current depressive episode were found to be significant predictors of the MoCA status in the multivariable comparisons. Conclusions: A positive MoCA screening for cognitive impairments among post-detoxification SAUD patients could also be related to comorbid agoraphobia and depressive episode rather than to SAUD itself. A comprehensive psychiatric assessment must be performed in SAUD patients so that other potential causes of cognitive deficits, in particular with regard to mood and anxiety disorders, can be identified and treated.},
address = {D'Hondt, Fabien, Unite CURE, Secretariat de Psychiatrie de l'enfant et de l'Adolescent, Hopital Fontan 1, CHU de Lille, CS 70001, 59037, Lille, France, Cedex},
annote = {From Duplicate 2 (Psychiatric comorbidities associated with a positive screening using the Montreal Cognitive Assessment (MoCA) test in subjects with severe alcohol use disorder - D'Hondt, Fabien; Lescut, Charles; Maurage, Pierre; Menard, Olivier; Gibour, Bernard; Cottencin, Olivier; Mont{\`{e}}gue, Sol{\`{e}}ne; Jardri, Renaud; Rolland, Benjamin)

From Duplicate 3 (Psychiatric comorbidities associated with a positive screening using the Montreal Cognitive Assessment (MoCA) test in subjects with severe alcohol use disorder - D'Hondt, Fabien; Lescut, Charles; Maurage, Pierre; Menard, Olivier; Gibour, Bernard; Cottencin, Olivier; Mont{\`{e}}gue, Sol{\`{e}}ne; Jardri, Renaud; Rolland, Benjamin)

Accession Number: 2018-47161-033. Partial author list: First Author & Affiliation: D'Hondt, Fabien; Univ. Lille, CNRS, UMR 9193–SCALab–Sciences Cognitives et Sciences Affectives, Lille, France. Release Date: 20181203. Publication Type: Journal (0100), Peer Reviewed Journal (0110). Format Covered: Electronic. Document Type: Journal Article. Language: EnglishMajor Descriptor: Alcohol Abuse; Cognitive Impairment; Comorbidity; Screening. Classification: Substance Abuse & Addiction (3233). Population: Human (10); Male (30); Female (40). Location: France. Age Group: Adulthood (18 yrs & older) (300). Tests & Measures: Adult ADHD Self-Report Scale; Barratt Impulsiveness Scale--French Version; Personality Diagnostic Questionnaire-4+--French Version; Mini International Neuropsychiatric Interview--French Version; Montreal Cognitive Assessment DOI: 10.1037/t27279-000. Methodology: Empirical Study; Quantitative Study. References Available: Y. Page Count: 4. Issue Publication Date: Oct 1, 2018. Publication History: First Posted Date: Aug 22, 2018; Accepted Date: Jul 9, 2018; Revised Date: Jul 3, 2018; First Submitted Date: May 9, 2018. Copyright Statement: All rights reserved. Elsevier B.V. 2018.},
author = {D'Hondt, Fabien and Lescut, Charles and Maurage, Pierre and Menard, Olivier and Gibour, Bernard and Cottencin, Olivier and Mont{\`{e}}gue, Sol{\`{e}}ne and Jardri, Renaud and Rolland, Benjamin},
doi = {10.1016/j.drugalcdep.2018.07.009},
file = {:C\:/Users/fabie/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/D'Hondt et al. - 2018 - Psychiatric comorbidities associated with a positive screening using the Montreal Cognitive Assessment (MoCA) te.pdf:pdf},
issn = {18790046},
journal = {Drug and Alcohol Dependence},
keywords = {Alcohol use disorder,Cognitive impairment,Comorbidity,MoCA},
month = {oct},
number = {May},
pages = {266--269},
pmid = {30153608},
publisher = {Elsevier},
title = {{Psychiatric comorbidities associated with a positive screening using the Montreal Cognitive Assessment (MoCA) test in subjects with severe alcohol use disorder}},
url = {https://doi.org/10.1016/j.drugalcdep.2018.07.009 https://search.ebscohost.com/login.aspx?direct=true&AuthType=ip,url,uid&db=psyh&AN=2018-47161-033&lang=fr&site=ehost-live orcid: 0000-0003-3663-1405 orcid: 0000-0003-0197-0810 orcid: 0000-0001-5683-0490 htt},
volume = {191},
year = {2018}
}

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Accordingly, this exploratory study examined whether psychiatric comorbid disorders can induce a positive MoCA screening among recently detoxified SAUD subjects. Methods: One hundred recently detoxified patients with SAUD were divided into two groups according to whether they presented cognitive deficits using the MoCA. Groups were compared for demographic data, SAUD severity, impulsivity, and psychiatric comorbidities. The significant parameters were then introduced in a logistic regression model to establish their relative contributions in a positive MoCA status in SAUD subjects. Results: Among the significant parameters revealed by the bivariable analyses, agoraphobia and current depressive episode were found to be significant predictors of the MoCA status in the multivariable comparisons. Conclusions: A positive MoCA screening for cognitive impairments among post-detoxification SAUD patients could also be related to comorbid agoraphobia and depressive episode rather than to SAUD itself. A comprehensive psychiatric assessment must be performed in SAUD patients so that other potential causes of cognitive deficits, in particular with regard to mood and anxiety disorders, can be identified and treated.","address":"D'Hondt, Fabien, Unite CURE, Secretariat de Psychiatrie de l'enfant et de l'Adolescent, Hopital Fontan 1, CHU de Lille, CS 70001, 59037, Lille, France, Cedex","annote":"From Duplicate 2 (Psychiatric comorbidities associated with a positive screening using the Montreal Cognitive Assessment (MoCA) test in subjects with severe alcohol use disorder - D'Hondt, Fabien; Lescut, Charles; Maurage, Pierre; Menard, Olivier; Gibour, Bernard; Cottencin, Olivier; Montègue, Solène; Jardri, Renaud; Rolland, Benjamin) From Duplicate 3 (Psychiatric comorbidities associated with a positive screening using the Montreal Cognitive Assessment (MoCA) test in subjects with severe alcohol use disorder - D'Hondt, Fabien; Lescut, Charles; Maurage, Pierre; Menard, Olivier; Gibour, Bernard; Cottencin, Olivier; Montègue, Solène; Jardri, Renaud; Rolland, Benjamin) Accession Number: 2018-47161-033. Partial author list: First Author & Affiliation: D'Hondt, Fabien; Univ. Lille, CNRS, UMR 9193–SCALab–Sciences Cognitives et Sciences Affectives, Lille, France. Release Date: 20181203. Publication Type: Journal (0100), Peer Reviewed Journal (0110). Format Covered: Electronic. Document Type: Journal Article. Language: EnglishMajor Descriptor: Alcohol Abuse; Cognitive Impairment; Comorbidity; Screening. Classification: Substance Abuse & Addiction (3233). Population: Human (10); Male (30); Female (40). Location: France. Age Group: Adulthood (18 yrs & older) (300). Tests & Measures: Adult ADHD Self-Report Scale; Barratt Impulsiveness Scale–French Version; Personality Diagnostic Questionnaire-4+–French Version; Mini International Neuropsychiatric Interview–French Version; Montreal Cognitive Assessment DOI: 10.1037/t27279-000. Methodology: Empirical Study; Quantitative Study. References Available: Y. Page Count: 4. Issue Publication Date: Oct 1, 2018. Publication History: First Posted Date: Aug 22, 2018; Accepted Date: Jul 9, 2018; Revised Date: Jul 3, 2018; First Submitted Date: May 9, 2018. Copyright Statement: All rights reserved. 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Conclusions: A positive MoCA screening for cognitive impairments among post-detoxification SAUD patients could also be related to comorbid agoraphobia and depressive episode rather than to SAUD itself. A comprehensive psychiatric assessment must be performed in SAUD patients so that other potential causes of cognitive deficits, in particular with regard to mood and anxiety disorders, can be identified and treated.},\naddress = {D'Hondt, Fabien, Unite CURE, Secretariat de Psychiatrie de l'enfant et de l'Adolescent, Hopital Fontan 1, CHU de Lille, CS 70001, 59037, Lille, France, Cedex},\nannote = {From Duplicate 2 (Psychiatric comorbidities associated with a positive screening using the Montreal Cognitive Assessment (MoCA) test in subjects with severe alcohol use disorder - D'Hondt, Fabien; Lescut, Charles; Maurage, Pierre; Menard, Olivier; Gibour, Bernard; Cottencin, Olivier; Mont{\\`{e}}gue, Sol{\\`{e}}ne; Jardri, Renaud; Rolland, Benjamin)\n\nFrom Duplicate 3 (Psychiatric comorbidities associated with a positive screening using the Montreal Cognitive Assessment (MoCA) test in subjects with severe alcohol use disorder - D'Hondt, Fabien; Lescut, Charles; Maurage, Pierre; Menard, Olivier; Gibour, Bernard; Cottencin, Olivier; Mont{\\`{e}}gue, Sol{\\`{e}}ne; Jardri, Renaud; Rolland, Benjamin)\n\nAccession Number: 2018-47161-033. 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