Cellular damage triggers mechano-chemical control of cell wall dynamics and patterned cell divisions in plant healing. Di Fino, L. M., Anjam, M. S., Besten, M., Mentzelopoulou, A., Papadakis, V., Zahid, N., Baez, L. A., Trozzi, N., Majda, M., Ma, X., Hamann, T., Sprakel, J., Moschou, P. N., Smith, R. S., & Marhavý, P. Developmental Cell, January, 2025. ![Cellular damage triggers mechano-chemical control of cell wall dynamics and patterned cell divisions in plant healing [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Reactivation of cell division is crucial for the regeneration of damaged tissues, which is a fundamental process across all multicellular organisms. However, the mechanisms underlying the activation of cell division in plants during regeneration remain poorly understood. Here, we show that single-cell endodermal ablation generates a transient change in the local mechanical pressure on neighboring pericycle cells to activate patterned cell division that is crucial for tissue regeneration in Arabidopsis roots. Moreover, we provide strong evidence that this process relies on the phytohormone ethylene. Thus, our results highlight a previously unrecognized role of mechano-chemical control in patterned cell division during regeneration in plants.
@article{di_fino_cellular_2025,
title = {Cellular damage triggers mechano-chemical control of cell wall dynamics and patterned cell divisions in plant healing},
issn = {1534-5807},
url = {https://www.sciencedirect.com/science/article/pii/S1534580724007718},
doi = {10.1016/j.devcel.2024.12.032},
abstract = {Reactivation of cell division is crucial for the regeneration of damaged tissues, which is a fundamental process across all multicellular organisms. However, the mechanisms underlying the activation of cell division in plants during regeneration remain poorly understood. Here, we show that single-cell endodermal ablation generates a transient change in the local mechanical pressure on neighboring pericycle cells to activate patterned cell division that is crucial for tissue regeneration in Arabidopsis roots. Moreover, we provide strong evidence that this process relies on the phytohormone ethylene. Thus, our results highlight a previously unrecognized role of mechano-chemical control in patterned cell division during regeneration in plants.},
urldate = {2025-02-21},
journal = {Developmental Cell},
author = {Di Fino, Luciano Martín and Anjam, Muhammad Shahzad and Besten, Maarten and Mentzelopoulou, Andriani and Papadakis, Vassilis and Zahid, Nageena and Baez, Luis Alonso and Trozzi, Nicola and Majda, Mateusz and Ma, Xuemin and Hamann, Thorsten and Sprakel, Joris and Moschou, Panagiotis N. and Smith, Richard S. and Marhavý, Peter},
month = jan,
year = {2025},
keywords = {cell division, cell wall, ethylene, mechanobiology, pectin, regeneration, single-cell laser ablation, xylem-pole-pericycle},
}
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