@ARTICLE{Di_Lullo2017-mb,
  title    = "The use of brain organoids to investigate neural development and
              disease",
  author   = "Di Lullo, Elizabeth and Kriegstein, Arnold R",
  abstract = "Understanding the development and dysfunction of the human brain
              is a major goal of neurobiology. Much of our current
              understanding of human brain development has been derived from
              the examination of post-mortem and pathological specimens,
              bolstered by observations of developing non-human primates and
              experimental studies focused largely on mouse models. However,
              these tissue specimens and model systems cannot fully capture the
              unique and dynamic features of human brain development. Recent
              advances in stem cell technologies that enable the generation of
              human brain organoids from pluripotent stem cells (PSCs) promise
              to profoundly change our understanding of the development of the
              human brain and enable a detailed study of the pathogenesis of
              inherited and acquired brain diseases.",
  journal  = "Nat Rev Neurosci",
  volume   =  18,
  number   =  10,
  pages    = "573--584",
  month    =  sep,
  year     =  2017,
  language = "en"
}

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