Process for preparing polycyclic heterocycles having a pyran ring. Dobson, T., A., Humber, L., G., Demerson, C., A., & Jirkovsky, I., L. 1977. Website abstract bibtex A process applicable to the preparation of a wide variety of novel polycyclic heterocycles having a newly formed pyran ring is disclosed. According to the process an aromatic nucleus bearing an ethanol group, for example, 3,4-dimethoxyphenethyl alcohol, is condensed with an aldehyde or ketone or a protected aldehyde or ketone, for example, aminoactaldehyde diethyl acetal, in the presence of an acid catalyst to afford the polycyclic heterocycle, for example, 6,7-dimethoxy-l-isochromanmethylamine. The new heterocycles so formed are useful for preparing derivatives having antiinflammatory, antibacterial or antifungal activities.
@misc{
title = {Process for preparing polycyclic heterocycles having a pyran ring},
type = {misc},
year = {1977},
websites = {http://worldwide.espacenet.com/publicationDetails/biblio?CC=US&NR=4036842A&KC=A&FT=D},
publisher = {American Home Products Corporation},
revision = {US 4036842},
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created = {2015-12-17T08:57:43.000Z},
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last_modified = {2015-12-17T08:57:43.000Z},
tags = {acetals_review,alpha_acetals},
read = {true},
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hidden = {false},
citation_key = {Dobson1977},
country = {US},
patent_owner = {American Home Products Corporation},
abstract = {A process applicable to the preparation of a wide variety of novel polycyclic heterocycles having a newly formed pyran ring is disclosed. According to the process an aromatic nucleus bearing an ethanol group, for example, 3,4-dimethoxyphenethyl alcohol, is condensed with an aldehyde or ketone or a protected aldehyde or ketone, for example, aminoactaldehyde diethyl acetal, in the presence of an acid catalyst to afford the polycyclic heterocycle, for example, 6,7-dimethoxy-l-isochromanmethylamine. The new heterocycles so formed are useful for preparing derivatives having antiinflammatory, antibacterial or antifungal activities.},
bibtype = {misc},
author = {Dobson, Thomas A and Humber, Leslie G and Demerson, Christopher A and Jirkovsky, Ivo L}
}
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