Process for preparing polycyclic heterocycles having a pyran ring. Dobson, T., A., Humber, L., G., Demerson, C., A., & Jirkovsky, I., L. 1977.
Process for preparing polycyclic heterocycles having a pyran ring [link]Website  abstract   bibtex   
A process applicable to the preparation of a wide variety of novel polycyclic heterocycles having a newly formed pyran ring is disclosed. According to the process an aromatic nucleus bearing an ethanol group, for example, 3,4-dimethoxyphenethyl alcohol, is condensed with an aldehyde or ketone or a protected aldehyde or ketone, for example, aminoactaldehyde diethyl acetal, in the presence of an acid catalyst to afford the polycyclic heterocycle, for example, 6,7-dimethoxy-l-isochromanmethylamine. The new heterocycles so formed are useful for preparing derivatives having antiinflammatory, antibacterial or antifungal activities.
@misc{
 title = {Process for preparing polycyclic heterocycles having a pyran ring},
 type = {misc},
 year = {1977},
 websites = {http://worldwide.espacenet.com/publicationDetails/biblio?CC=US&NR=4036842A&KC=A&FT=D},
 publisher = {American Home Products Corporation},
 revision = {US 4036842},
 id = {eb5002a2-0ac1-321f-8a55-59ee6c78984d},
 created = {2015-12-17T08:57:43.000Z},
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 last_modified = {2015-12-17T08:57:43.000Z},
 tags = {acetals_review,alpha_acetals},
 read = {true},
 starred = {false},
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 hidden = {false},
 citation_key = {Dobson1977},
 country = {US},
 patent_owner = {American Home Products Corporation},
 abstract = {A process applicable to the preparation of a wide variety of novel polycyclic heterocycles having a newly formed pyran ring is disclosed. According to the process an aromatic nucleus bearing an ethanol group, for example, 3,4-dimethoxyphenethyl alcohol, is condensed with an aldehyde or ketone or a protected aldehyde or ketone, for example, aminoactaldehyde diethyl acetal, in the presence of an acid catalyst to afford the polycyclic heterocycle, for example, 6,7-dimethoxy-l-isochromanmethylamine. The new heterocycles so formed are useful for preparing derivatives having antiinflammatory, antibacterial or antifungal activities.},
 bibtype = {misc},
 author = {Dobson, Thomas A and Humber, Leslie G and Demerson, Christopher A and Jirkovsky, Ivo L}
}
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