Are basic auditory processes involved in source-monitoring deficits in patients with schizophrenia?. Dondé, C., Mondino, M., Leitman, D. I., Javitt, D. C., Suaud-Chagny, M., D'Amato, T., Brunelin, J., & Haesebaert, F. Schizophrenia Research, 210:135–142, August, 2019. Publisher: Elsevier Science
Paper doi abstract bibtex Patients with schizophrenia (SZ) display deficits in both basic non-verbal auditory processing and source-monitoring of speech. To date, the contributions of basic auditory deficits to higher-order cognitive impairments, such as source-monitoring, and to clinical symptoms have yet to be elucidated. The aim of this study was to investigate the deficits and relationships between basic auditory functions, source-monitoring performances, and clinical symptom severity in SZ. Auditory processing of 4 psychoacoustic features (pitch, intensity, amplitude, length) and 2 types of source-monitoring (internal and reality monitoring) performances were assessed in 29 SZ and 29 healthy controls. Clinical symptoms were evaluated in patients with the Positive And Negative Syndrome Scale. Compared to the controls, SZ individuals in showed significant reductions in both global basic auditory processing (p \textless .0005, d = 1.16) and source-monitoring (p \textless .0005, d = 1.24) abilities. Both deficits correlated significantly in patients and across groups (all p \textless .05). Pitch processing skills were negatively correlated with positive symptom severity (r = −0.4, p \textless .05). A step-wise regression analysis showed that pitch discrimination was a significant predictor of source-monitoring performance. These results suggest that cognitive mechanisms associated with the discrimination of basic auditory features are most compromised in patients with source-monitoring disability. Basic auditory processing may index pathophysiological processes that are critical for optimal source-monitoring in schizophrenia and that are involved in positive symptoms. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
@article{donde_are_2019,
title = {Are basic auditory processes involved in source-monitoring deficits in patients with schizophrenia?},
volume = {210},
issn = {0920-9964},
url = {https://search.ebscohost.com/login.aspx?direct=true&AuthType=ip,uid&db=psyh&AN=2019-31895-001&site=ehost-live},
doi = {10.1016/j.schres.2019.05.034},
abstract = {Patients with schizophrenia (SZ) display deficits in both basic non-verbal auditory processing and source-monitoring of speech. To date, the contributions of basic auditory deficits to higher-order cognitive impairments, such as source-monitoring, and to clinical symptoms have yet to be elucidated. The aim of this study was to investigate the deficits and relationships between basic auditory functions, source-monitoring performances, and clinical symptom severity in SZ. Auditory processing of 4 psychoacoustic features (pitch, intensity, amplitude, length) and 2 types of source-monitoring (internal and reality monitoring) performances were assessed in 29 SZ and 29 healthy controls. Clinical symptoms were evaluated in patients with the Positive And Negative Syndrome Scale. Compared to the controls, SZ individuals in showed significant reductions in both global basic auditory processing (p {\textless} .0005, d = 1.16) and source-monitoring (p {\textless} .0005, d = 1.24) abilities. Both deficits correlated significantly in patients and across groups (all p {\textless} .05). Pitch processing skills were negatively correlated with positive symptom severity (r = −0.4, p {\textless} .05). A step-wise regression analysis showed that pitch discrimination was a significant predictor of source-monitoring performance. These results suggest that cognitive mechanisms associated with the discrimination of basic auditory features are most compromised in patients with source-monitoring disability. Basic auditory processing may index pathophysiological processes that are critical for optimal source-monitoring in schizophrenia and that are involved in positive symptoms. (PsycInfo Database Record (c) 2021 APA, all rights reserved)},
journal = {Schizophrenia Research},
author = {Dondé, Clément and Mondino, Marine and Leitman, David I. and Javitt, Daniel C. and Suaud-Chagny, Marie-Françoise and D'Amato, Thierry and Brunelin, Jérôme and Haesebaert, Frédéric},
month = aug,
year = {2019},
note = {Publisher: Elsevier Science},
keywords = {Adult, Auditory Displays, Auditory Perception, Auditory Perceptual Disorders, Basic auditory processing, Cognitive Dysfunction, Cognitive Impairment, Female, Humans, Imagination, Male, Middle Aged, Oral Communication, Positive and Negative Symptoms, Positive symptoms, Schizophrenia, Severity (Disorders), Source Monitoring, Source-monitoring, Speech Perception, Tone-matching, Young Adult},
pages = {135--142},
}
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The aim of this study was to investigate the deficits and relationships between basic auditory functions, source-monitoring performances, and clinical symptom severity in SZ. Auditory processing of 4 psychoacoustic features (pitch, intensity, amplitude, length) and 2 types of source-monitoring (internal and reality monitoring) performances were assessed in 29 SZ and 29 healthy controls. Clinical symptoms were evaluated in patients with the Positive And Negative Syndrome Scale. Compared to the controls, SZ individuals in showed significant reductions in both global basic auditory processing (p \\textless .0005, d = 1.16) and source-monitoring (p \\textless .0005, d = 1.24) abilities. Both deficits correlated significantly in patients and across groups (all p \\textless .05). Pitch processing skills were negatively correlated with positive symptom severity (r = −0.4, p \\textless .05). 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