@article{RN114,
   author = {Duncan, J. L. and Davalos, R. V.},
   title = {A review: Dielectrophoresis for characterizing and separating similar cell subpopulations based on bioelectric property changes due to disease progression and therapy assessment},
   journal = {Electrophoresis},
   volume = {42},
   number = {23},
   pages = {2423-2444},
   note = {1522-2683
Duncan, Josie L
Orcid: 0000-0002-4743-1540
Davalos, Rafael V
Orcid: 0000-0003-1503-9509
Journal Article
Research Support, Non-U.S. Gov't
Review
Germany
2021/10/06
Electrophoresis. 2021 Dec;42(23):2423-2444. doi: 10.1002/elps.202100135. Epub 2021 Oct 20.},
   abstract = {This paper reviews the use of dielectrophoresis for high-fidelity separations and characterizations of subpopulations to highlight the recent advances in the electrokinetic field as well as provide insight into its progress toward commercialization. The role of cell subpopulations in heterogeneous clinical samples has been studied to deduce their role in disease progression and therapy resistance for instances such as cancer, tissue regeneration, and bacterial infection. Dielectrophoresis (DEP), a label-free electrokinetic technique, has been used to characterize and separate target subpopulations from mixed samples to determine disease severity, cell stemness, and drug efficacy. Despite its high sensitivity to characterize similar or related cells based on their differing bioelectric signatures, DEP has been slowly adopted both commercially and clinically. This review addresses the use of dielectrophoresis for the identification of target cell subtypes in stem cells, cancer cells, blood cells, and bacterial cells dependent on cell state and therapy exposure and addresses commercialization efforts in light of its sensitivity and future perspectives of the technology, both commercially and academically.},
   keywords = {Animals
Disease Progression
*Electrophoresis/methods
Humans
*Neoplasms/pathology/therapy
Blood cells
Cancer cells
Dielectrophoresis
Stem cells
Subpopulation},
   ISSN = {0173-0835},
   DOI = {10.1002/elps.202100135},
   year = {2021},
   type = {Journal Article}
}

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V."],"bibdata":{"bibtype":"article","type":"Journal Article","author":[{"propositions":[],"lastnames":["Duncan"],"firstnames":["J.","L."],"suffixes":[]},{"propositions":[],"lastnames":["Davalos"],"firstnames":["R.","V."],"suffixes":[]}],"title":"A review: Dielectrophoresis for characterizing and separating similar cell subpopulations based on bioelectric property changes due to disease progression and therapy assessment","journal":"Electrophoresis","volume":"42","number":"23","pages":"2423-2444","note":"1522-2683 Duncan, Josie L Orcid: 0000-0002-4743-1540 Davalos, Rafael V Orcid: 0000-0003-1503-9509 Journal Article Research Support, Non-U.S. Gov't Review Germany 2021/10/06 Electrophoresis. 2021 Dec;42(23):2423-2444. doi: 10.1002/elps.202100135. 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V.},\n title = {A review: Dielectrophoresis for characterizing and separating similar cell subpopulations based on bioelectric property changes due to disease progression and therapy assessment},\n journal = {Electrophoresis},\n volume = {42},\n number = {23},\n pages = {2423-2444},\n note = {1522-2683\nDuncan, Josie L\nOrcid: 0000-0002-4743-1540\nDavalos, Rafael V\nOrcid: 0000-0003-1503-9509\nJournal Article\nResearch Support, Non-U.S. Gov't\nReview\nGermany\n2021/10/06\nElectrophoresis. 2021 Dec;42(23):2423-2444. doi: 10.1002/elps.202100135. Epub 2021 Oct 20.},\n abstract = {This paper reviews the use of dielectrophoresis for high-fidelity separations and characterizations of subpopulations to highlight the recent advances in the electrokinetic field as well as provide insight into its progress toward commercialization. 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