Amygdala microcircuits controlling learned fear. Duvarci, S. and Pare, D. Neuron, 82(5):966--980, June, 2014. 00000
Amygdala microcircuits controlling learned fear [link]Paper  doi  abstract   bibtex   
We review recent work on the role of intrinsic amygdala networks in the regulation of classically conditioned defensive behaviors, commonly known as conditioned fear. These new developments highlight how conditioned fear depends on far more complex networks than initially envisioned. Indeed, multiple parallel inhibitory and excitatory circuits are differentially recruited during the expression versus extinction of conditioned fear. Moreover, shifts between expression and extinction circuits involve coordinated interactions with different regions of the medial prefrontal cortex. However, key areas of uncertainty remain, particularly with respect to the connectivity of the different cell types. Filling these gaps in our knowledge is important because much evidence indicates that human anxiety disorders results from an abnormal regulation of the networks supporting fear learning.
@article{duvarci_amygdala_2014,
	title = {Amygdala microcircuits controlling learned fear},
	volume = {82},
	issn = {0896-6273},
	url = {http://dx.doi.org/10.1016/j.neuron.2014.04.042},
	doi = {10.1016/j.neuron.2014.04.042},
	abstract = {We review recent work on the role of intrinsic amygdala networks in the
regulation of classically conditioned defensive behaviors, commonly known
as conditioned fear. These new developments highlight how conditioned fear
depends on far more complex networks than initially envisioned. Indeed,
multiple parallel inhibitory and excitatory circuits are differentially
recruited during the expression versus extinction of conditioned fear.
Moreover, shifts between expression and extinction circuits involve
coordinated interactions with different regions of the medial prefrontal
cortex. However, key areas of uncertainty remain, particularly with
respect to the connectivity of the different cell types. Filling these
gaps in our knowledge is important because much evidence indicates that
human anxiety disorders results from an abnormal regulation of the
networks supporting fear learning.},
	number = {5},
	journal = {Neuron},
	author = {Duvarci, Sevil and Pare, Denis},
	month = jun,
	year = {2014},
	note = {00000},
	keywords = {Sep 20 import, duplicate},
	pages = {966--980}
}
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