A prospective longitudinal model predicting early adult alcohol problems: evidence for a robust externalizing pathway. Edwards, A C, Gardner, C O, Hickman, M, & Kendler, K S Psychol. Med., 46(5):957--968, April, 2016. 00009![A prospective longitudinal model predicting early adult alcohol problems: evidence for a robust externalizing pathway [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex BACKGROUND: Risk factors for alcohol problems (AP) include biological and environmental factors that are relevant across development. The pathways through which these factors are related, and how they lead to AP, are optimally considered in the context of a comprehensive developmental model. METHOD: Using data from a prospectively assessed, population-based UK cohort, we constructed a structural equation model that integrated risk factors reflecting individual, family and peer/community-level constructs across childhood, adolescence and young adulthood. These variables were used to predict AP at the age of 20 years. RESULTS: The final model explained over 30% of the variance in liability to age 20 years AP. Most prominent in the model was an externalizing pathway to AP, with conduct problems, sensation seeking, AP at age 17.5 years and illicit substance use acting as robust predictors. In conjunction with these individual-level risk factors, familial AP, peer relationships and low parental monitoring also predicted AP. Internalizing problems were less consistently associated with AP. Some risk factors previously identified were not associated with AP in the context of this comprehensive model. CONCLUSIONS: The etiology of young adult AP is complex, influenced by risk factors that manifest across development. The most prominent pathway to AP is via externalizing and related behaviors. These findings underscore the importance of jointly assessing both biologically influenced and environmental risk factors for AP in a developmental context.
@article{edwards_prospective_2016,
title = {A prospective longitudinal model predicting early adult alcohol problems: evidence for a robust externalizing pathway},
volume = {46},
issn = {0033-2917},
url = {http://dx.doi.org/10.1017/S0033291715002457},
doi = {10.1017/S0033291715002457},
abstract = {BACKGROUND: Risk factors for alcohol problems (AP) include biological and
environmental factors that are relevant across development. The pathways
through which these factors are related, and how they lead to AP, are
optimally considered in the context of a comprehensive developmental
model. METHOD: Using data from a prospectively assessed, population-based
UK cohort, we constructed a structural equation model that integrated risk
factors reflecting individual, family and peer/community-level constructs
across childhood, adolescence and young adulthood. These variables were
used to predict AP at the age of 20 years. RESULTS: The final model
explained over 30\% of the variance in liability to age 20 years AP. Most
prominent in the model was an externalizing pathway to AP, with conduct
problems, sensation seeking, AP at age 17.5 years and illicit substance
use acting as robust predictors. In conjunction with these
individual-level risk factors, familial AP, peer relationships and low
parental monitoring also predicted AP. Internalizing problems were less
consistently associated with AP. Some risk factors previously identified
were not associated with AP in the context of this comprehensive model.
CONCLUSIONS: The etiology of young adult AP is complex, influenced by risk
factors that manifest across development. The most prominent pathway to AP
is via externalizing and related behaviors. These findings underscore the
importance of jointly assessing both biologically influenced and
environmental risk factors for AP in a developmental context.},
number = {5},
journal = {Psychol. Med.},
author = {Edwards, A C and Gardner, C O and Hickman, M and Kendler, K S},
month = apr,
year = {2016},
note = {00009},
keywords = {Alcohol problems, Avon Longitudinal Study of Parents and Children, Mental Health Diversity, development, externalizing pathways},
pages = {957--968}
}
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The pathways through which these factors are related, and how they lead to AP, are optimally considered in the context of a comprehensive developmental model. METHOD: Using data from a prospectively assessed, population-based UK cohort, we constructed a structural equation model that integrated risk factors reflecting individual, family and peer/community-level constructs across childhood, adolescence and young adulthood. These variables were used to predict AP at the age of 20 years. RESULTS: The final model explained over 30% of the variance in liability to age 20 years AP. Most prominent in the model was an externalizing pathway to AP, with conduct problems, sensation seeking, AP at age 17.5 years and illicit substance use acting as robust predictors. In conjunction with these individual-level risk factors, familial AP, peer relationships and low parental monitoring also predicted AP. Internalizing problems were less consistently associated with AP. Some risk factors previously identified were not associated with AP in the context of this comprehensive model. CONCLUSIONS: The etiology of young adult AP is complex, influenced by risk factors that manifest across development. The most prominent pathway to AP is via externalizing and related behaviors. These findings underscore the importance of jointly assessing both biologically influenced and environmental risk factors for AP in a developmental context.","number":"5","journal":"Psychol. Med.","author":[{"propositions":[],"lastnames":["Edwards"],"firstnames":["A","C"],"suffixes":[]},{"propositions":[],"lastnames":["Gardner"],"firstnames":["C","O"],"suffixes":[]},{"propositions":[],"lastnames":["Hickman"],"firstnames":["M"],"suffixes":[]},{"propositions":[],"lastnames":["Kendler"],"firstnames":["K","S"],"suffixes":[]}],"month":"April","year":"2016","note":"00009","keywords":"Alcohol problems, Avon Longitudinal Study of Parents and Children, Mental Health Diversity, development, externalizing pathways","pages":"957--968","bibtex":"@article{edwards_prospective_2016,\n\ttitle = {A prospective longitudinal model predicting early adult alcohol problems: evidence for a robust externalizing pathway},\n\tvolume = {46},\n\tissn = {0033-2917},\n\turl = {http://dx.doi.org/10.1017/S0033291715002457},\n\tdoi = {10.1017/S0033291715002457},\n\tabstract = {BACKGROUND: Risk factors for alcohol problems (AP) include biological and\nenvironmental factors that are relevant across development. The pathways\nthrough which these factors are related, and how they lead to AP, are\noptimally considered in the context of a comprehensive developmental\nmodel. METHOD: Using data from a prospectively assessed, population-based\nUK cohort, we constructed a structural equation model that integrated risk\nfactors reflecting individual, family and peer/community-level constructs\nacross childhood, adolescence and young adulthood. These variables were\nused to predict AP at the age of 20 years. RESULTS: The final model\nexplained over 30\\% of the variance in liability to age 20 years AP. Most\nprominent in the model was an externalizing pathway to AP, with conduct\nproblems, sensation seeking, AP at age 17.5 years and illicit substance\nuse acting as robust predictors. In conjunction with these\nindividual-level risk factors, familial AP, peer relationships and low\nparental monitoring also predicted AP. Internalizing problems were less\nconsistently associated with AP. Some risk factors previously identified\nwere not associated with AP in the context of this comprehensive model.\nCONCLUSIONS: The etiology of young adult AP is complex, influenced by risk\nfactors that manifest across development. The most prominent pathway to AP\nis via externalizing and related behaviors. These findings underscore the\nimportance of jointly assessing both biologically influenced and\nenvironmental risk factors for AP in a developmental context.},\n\tnumber = {5},\n\tjournal = {Psychol. 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