A 6-year longitudinal study of predictors for suicide attempts in major depressive disorder. Eikelenboom, M., Beekman, A. T. F., Penninx, B. W. J. H., & Smit, J. H. Psychological Medicine, 49(6):911–921, April, 2019.
Paper doi abstract bibtex Abstract Background Major depressive disorder (MDD), represent a major source of risk for suicidality. However, knowledge about risk factors for future suicide attempts (SAs) within MDD is limited. The present longitudinal study examined a wide range of putative non-clinical risk factors (demographic, social, lifestyle, personality) and clinical risk factors (depressive and suicidal indicators) for future SAs among persons with MDD. Furthermore, we examined the relationship between a number of significant predictors and the incidence of a future SA. Methods Data are from 1713 persons (18–65 years) with a lifetime MDD at the baseline measurement of the Netherlands Study of Depression and Anxiety who were subsequently followed up 2, 4 and 6 years. SAs were assessed in the face-to-face measurements. Cox proportional hazard regression analyses were used to examine a wide range of possible non-clinical and clinical predictors for subsequent SAs during 6-year follow-up. Results Over a period of 6 years, 3.4% of the respondents attempted suicide. Younger age, lower education, unemployment, insomnia, antidepressant use, a previous SA and current suicidal thoughts independently predicted a future SA. The number of significant risk factors (ranging from 0 to 7) linearly predicted the incidence of future SAs: in those with 0 predictors the SA incidence was 0%, which increased to 32% incidence in those with 6+ predictors. Conclusion Of the non-clinical factors, particularly socio-economic factors predicted a SA independently. Furthermore, preexisting suicidal ideation and insomnia appear to be important clinical risk factors for subsequent SA that are open to preventative intervention.
@article{eikelenboom_6-year_2019,
title = {A 6-year longitudinal study of predictors for suicide attempts in major depressive disorder},
volume = {49},
issn = {0033-2917, 1469-8978},
url = {https://www.cambridge.org/core/product/identifier/S0033291718001423/type/journal_article},
doi = {10.1017/S0033291718001423},
abstract = {Abstract
Background
Major depressive disorder (MDD), represent a major source of risk for suicidality. However, knowledge about risk factors for future suicide attempts (SAs) within MDD is limited. The present longitudinal study examined a wide range of putative non-clinical risk factors (demographic, social, lifestyle, personality) and clinical risk factors (depressive and suicidal indicators) for future SAs among persons with MDD. Furthermore, we examined the relationship between a number of significant predictors and the incidence of a future SA.
Methods
Data are from 1713 persons (18–65 years) with a lifetime MDD at the baseline measurement of the Netherlands Study of Depression and Anxiety who were subsequently followed up 2, 4 and 6 years. SAs were assessed in the face-to-face measurements. Cox proportional hazard regression analyses were used to examine a wide range of possible non-clinical and clinical predictors for subsequent SAs during 6-year follow-up.
Results
Over a period of 6 years, 3.4\% of the respondents attempted suicide. Younger age, lower education, unemployment, insomnia, antidepressant use, a previous SA and current suicidal thoughts independently predicted a future SA. The number of significant risk factors (ranging from 0 to 7) linearly predicted the incidence of future SAs: in those with 0 predictors the SA incidence was 0\%, which increased to 32\% incidence in those with 6+ predictors.
Conclusion
Of the non-clinical factors, particularly socio-economic factors predicted a SA independently. Furthermore, preexisting suicidal ideation and insomnia appear to be important clinical risk factors for subsequent SA that are open to preventative intervention.},
language = {en},
number = {6},
urldate = {2023-04-12},
journal = {Psychological Medicine},
author = {Eikelenboom, Merijn and Beekman, Aartjan T. F. and Penninx, Brenda W. J. H. and Smit, Johannes H.},
month = apr,
year = {2019},
keywords = {MDD, NESDA, Netherlands Study of Depression and Anxiety, SPSS},
pages = {911--921},
}
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The present longitudinal study examined a wide range of putative non-clinical risk factors (demographic, social, lifestyle, personality) and clinical risk factors (depressive and suicidal indicators) for future SAs among persons with MDD. Furthermore, we examined the relationship between a number of significant predictors and the incidence of a future SA. Methods Data are from 1713 persons (18–65 years) with a lifetime MDD at the baseline measurement of the Netherlands Study of Depression and Anxiety who were subsequently followed up 2, 4 and 6 years. SAs were assessed in the face-to-face measurements. Cox proportional hazard regression analyses were used to examine a wide range of possible non-clinical and clinical predictors for subsequent SAs during 6-year follow-up. Results Over a period of 6 years, 3.4% of the respondents attempted suicide. Younger age, lower education, unemployment, insomnia, antidepressant use, a previous SA and current suicidal thoughts independently predicted a future SA. The number of significant risk factors (ranging from 0 to 7) linearly predicted the incidence of future SAs: in those with 0 predictors the SA incidence was 0%, which increased to 32% incidence in those with 6+ predictors. Conclusion Of the non-clinical factors, particularly socio-economic factors predicted a SA independently. Furthermore, preexisting suicidal ideation and insomnia appear to be important clinical risk factors for subsequent SA that are open to preventative intervention.","language":"en","number":"6","urldate":"2023-04-12","journal":"Psychological Medicine","author":[{"propositions":[],"lastnames":["Eikelenboom"],"firstnames":["Merijn"],"suffixes":[]},{"propositions":[],"lastnames":["Beekman"],"firstnames":["Aartjan","T.","F."],"suffixes":[]},{"propositions":[],"lastnames":["Penninx"],"firstnames":["Brenda","W.","J.","H."],"suffixes":[]},{"propositions":[],"lastnames":["Smit"],"firstnames":["Johannes","H."],"suffixes":[]}],"month":"April","year":"2019","keywords":"MDD, NESDA, Netherlands Study of Depression and Anxiety, SPSS","pages":"911–921","bibtex":"@article{eikelenboom_6-year_2019,\n\ttitle = {A 6-year longitudinal study of predictors for suicide attempts in major depressive disorder},\n\tvolume = {49},\n\tissn = {0033-2917, 1469-8978},\n\turl = {https://www.cambridge.org/core/product/identifier/S0033291718001423/type/journal_article},\n\tdoi = {10.1017/S0033291718001423},\n\tabstract = {Abstract\n \n Background\n Major depressive disorder (MDD), represent a major source of risk for suicidality. However, knowledge about risk factors for future suicide attempts (SAs) within MDD is limited. The present longitudinal study examined a wide range of putative non-clinical risk factors (demographic, social, lifestyle, personality) and clinical risk factors (depressive and suicidal indicators) for future SAs among persons with MDD. Furthermore, we examined the relationship between a number of significant predictors and the incidence of a future SA.\n \n \n Methods\n Data are from 1713 persons (18–65 years) with a lifetime MDD at the baseline measurement of the Netherlands Study of Depression and Anxiety who were subsequently followed up 2, 4 and 6 years. SAs were assessed in the face-to-face measurements. Cox proportional hazard regression analyses were used to examine a wide range of possible non-clinical and clinical predictors for subsequent SAs during 6-year follow-up.\n \n \n Results\n Over a period of 6 years, 3.4\\% of the respondents attempted suicide. Younger age, lower education, unemployment, insomnia, antidepressant use, a previous SA and current suicidal thoughts independently predicted a future SA. The number of significant risk factors (ranging from 0 to 7) linearly predicted the incidence of future SAs: in those with 0 predictors the SA incidence was 0\\%, which increased to 32\\% incidence in those with 6+ predictors.\n \n \n Conclusion\n Of the non-clinical factors, particularly socio-economic factors predicted a SA independently. Furthermore, preexisting suicidal ideation and insomnia appear to be important clinical risk factors for subsequent SA that are open to preventative intervention.},\n\tlanguage = {en},\n\tnumber = {6},\n\turldate = {2023-04-12},\n\tjournal = {Psychological Medicine},\n\tauthor = {Eikelenboom, Merijn and Beekman, Aartjan T. F. and Penninx, Brenda W. J. H. and Smit, Johannes H.},\n\tmonth = apr,\n\tyear = {2019},\n\tkeywords = {MDD, NESDA, Netherlands Study of Depression and Anxiety, SPSS},\n\tpages = {911--921},\n}\n\n","author_short":["Eikelenboom, M.","Beekman, A. T. F.","Penninx, B. W. J. H.","Smit, J. 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