Cardiac MR elastography: comparison with left ventricular pressure measurement. Elgeti, T., Laule, M., Kaufels, N., Schnorr, J., Hamm, B., Samani, A., Braun, J.R., & Sack, I. J Cardiovasc Magn Reson, 11:44, 2009.
Cardiac MR elastography: comparison with left ventricular pressure measurement. [link]Paper  doi  abstract   bibtex   
To compare magnetic resonance elastography (MRE) with ventricular pressure changes in an animal model.Three pigs of different cardiac physiology (weight, 25 to 53 kg; heart rate, 61 to 93 bpm; left ventricular [LV] end-diastolic volume, 35 to 70 ml) were subjected to invasive LV pressure measurement by catheter and noninvasive cardiac MRE. Cardiac MRE was performed in a short-axis view of the heart and applying a 48.3-Hz shear-wave stimulus. Relative changes in LV-shear wave amplitudes during the cardiac cycle were analyzed. Correlation coefficients between wave amplitudes and LV pressure as well as between wave amplitudes and LV diameter were determined.A relationship between MRE and LV pressure was observed in all three animals (R2 >or= 0.76). No correlation was observed between MRE and LV diameter (R2
@article{ Elgeti2009,
  author = {Elgeti, Thomas and Laule, Michael and Kaufels, Nikola and Schnorr,
	J�rg and Hamm, Bernd and Samani, Abbas and Braun, J�rgen and Sack,
	Ingolf},
  title = {Cardiac MR elastography: comparison with left ventricular pressure
	measurement.},
  journal = {J Cardiovasc Magn Reson},
  year = {2009},
  volume = {11},
  pages = {44},
  abstract = {To compare magnetic resonance elastography (MRE) with ventricular
	pressure changes in an animal model.Three pigs of different cardiac
	physiology (weight, 25 to 53 kg; heart rate, 61 to 93 bpm; left ventricular
	[LV] end-diastolic volume, 35 to 70 ml) were subjected to invasive
	LV pressure measurement by catheter and noninvasive cardiac MRE.
	Cardiac MRE was performed in a short-axis view of the heart and applying
	a 48.3-Hz shear-wave stimulus. Relative changes in LV-shear wave
	amplitudes during the cardiac cycle were analyzed. Correlation coefficients
	between wave amplitudes and LV pressure as well as between wave amplitudes
	and LV diameter were determined.A relationship between MRE and LV
	pressure was observed in all three animals (R2 >or= 0.76). No correlation
	was observed between MRE and LV diameter (R2 <or= 0.15). Instead,
	shear wave amplitudes decreased 102 +/- 58 ms earlier than LV diameters
	at systole and amplitudes increased 175 +/- 40 ms before LV dilatation
	at diastole. Amplitude ratios between diastole and systole ranged
	from 2.0 to 2.8, corresponding to LV pressure differences of 60 to
	73 mmHg.Externally induced shear waves provide information reflecting
	intraventricular pressure changes which, if substantiated in further
	experiments, has potential to make cardiac MRE a unique noninvasive
	imaging modality for measuring pressure-volume function of the heart.},
  doi = {10.1186/1532-429X-11-44},
  institution = {Department of Radiology, Charit� - Universit�tsmedizin Berlin, Campus
	Mitte, Charit�platz 1, 10117 Berlin, Germany. thomas.elgeti@charite.de},
  keywords = {Animals; Cardiac Catheterization; Elasticity Imaging Techniques; Magnetic
	Resonance Imaging, Cine; Models, Animal; Predictive Value of Tests;
	Swine; Swine, Miniature; Time Factors; Ventricular Function, Left;
	Ventricular Pressure},
  language = {eng},
  medline-pst = {epublish},
  owner = {Heiko},
  pii = {1532-429X-11-44},
  pmid = {19900266},
  timestamp = {2013.07.26},
  url = {http://dx.doi.org/10.1186/1532-429X-11-44}
}

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