@ARTICLE{Elias2008-av,
  title    = "Gap junctions: multifaceted regulators of embryonic cortical
              development",
  author   = "Elias, Laura A B and Kriegstein, Arnold R",
  abstract = "The morphological development of the cerebral cortex from a
              primitive neuroepithelium into a complex laminar structure
              underlying higher cognition must rely on a network of
              intercellular signaling. Gap junctions are widely expressed
              during embryonic development and provide a means of cell-cell
              contact and communication. We review the roles of gap junctions
              in regulating the proliferation of neural progenitors as well as
              the migration and differentiation of young neurons in the
              embryonic cerebral cortex. There is substantial evidence that
              although gap junctions act in the classical manner coupling
              neural progenitors, they also act as hemichannels mediating the
              spread of calcium waves across progenitor cell populations and as
              adhesive molecules aiding neuronal migration. Gap junctions are
              thus emerging as multifaceted regulators of cortical development
              playing diverse roles in intercellular communication.",
  journal  = "Trends Neurosci",
  volume   =  31,
  number   =  5,
  pages    = "243--250",
  month    =  apr,
  year     =  2008,
  language = "en"
}

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