Does sugammadex facilitate recovery after outpatient tonsillectomy in children?. El sayed M. & Hassan S. 2016.
Does sugammadex facilitate recovery after outpatient tonsillectomy in children? [link]Paper  abstract   bibtex   
Introduction Sugammadex is an efficient reversal agent at any time, after neuromuscular blockade. It provides complete reversal for light or deep block facilitating rapid airway control and decreases anesthesia recovery period in outpatient surgeries in children. Patient and methods After ethical committee approval, informed consent and sample size calculation, 70 patients planned for outpatient total bilateral tonsillectomy were divided randomly into 2 groups. Group S (n = 35) received 2 mg/kg sugammadex to reversing NMB achieved by rocuronium. Group N (n = 35) received 0.05 mg/kg neostigmine and atropine sulfate 0.01 mg/kg, and extubation time (time from administration of reversal agent to time of extubation), train-of-four ratio, time to reach train-of-four \textgreater0.9, and side effects were recorded. Results There was no significant difference in demographic variables. TOF ratio after reversing was a statistically less in group S than in group N (p \textless 0.05). The time when TOF rate exceeded 0.9 and extubation time were less in group S than in group N with significant difference (p \textless 0.05). No adverse effect was recorded in both groups. Conclusions Sugammadex has created a novel rapid, effective and reliable retrieval from NMB with rocuronium in children undergoing tonsillectomy with no side effects. Copyright © 2016
@misc{el_sayed_m._does_2016,
	title = {Does sugammadex facilitate recovery after outpatient tonsillectomy in children?},
	url = {http://www.sciencedirect.com/},
	abstract = {Introduction Sugammadex is an efficient reversal agent at any time, after neuromuscular blockade. It provides complete reversal for light or deep block facilitating rapid airway control and decreases anesthesia recovery period in outpatient surgeries in children. Patient and methods After ethical committee approval, informed consent and sample size calculation, 70 patients planned for outpatient total bilateral tonsillectomy were divided randomly into 2 groups. Group S (n = 35) received 2 mg/kg sugammadex to reversing NMB achieved by rocuronium. Group N (n = 35) received 0.05 mg/kg neostigmine and atropine sulfate 0.01 mg/kg, and extubation time (time from administration of reversal agent to time of extubation), train-of-four ratio, time to reach train-of-four {\textgreater}0.9, and side effects were recorded. Results There was no significant difference in demographic variables. TOF ratio after reversing was a statistically less in group S than in group N (p {\textless} 0.05). The time when TOF rate exceeded 0.9 and extubation time were less in group S than in group N with significant difference (p {\textless} 0.05). No adverse effect was recorded in both groups. Conclusions Sugammadex has created a novel rapid, effective and reliable retrieval from NMB with rocuronium in children undergoing tonsillectomy with no side effects. Copyright © 2016},
	journal = {Egyptian Journal of Anaesthesia},
	author = {{El sayed M.} and {Hassan S.}},
	year = {2016},
	keywords = {*anesthetic recovery, *neostigmine, *outpatient, *remission, *sugammadex, *sugammadex/ae [Adverse Drug Reaction], *sugammadex/cm [Drug Comparison], *sugammadex/ct [Clinical Trial], *tonsillectomy, Child, absence of side effects, ambulatory surgery, article, atropine, atropine/ae [Adverse Drug Reaction], atropine/ct [Clinical Trial], blurred vision/si [Side Effect], bradycardia/si [Side Effect], bronchoconstriction/si [Side Effect], calculation, controlled study, convalescence, drug efficacy, edrophonium/ae [Adverse Drug Reaction], edrophonium/cb [Drug Combination], edrophonium/ct [Clinical Trial], extubation, female, fentanyl, heart arrhythmia/si [Side Effect], heart rate, human, hypersalivation/si [Side Effect], hypotension/si [Side Effect], information retrieval, informed consent, major clinical study, male, muscarinic receptor blocking agent/ae [Adverse Drug Reaction], nausea/si [Side Effect], neostigmine/ae [Adverse Drug Reaction], neostigmine/cb [Drug Combination], neostigmine/cm [Drug Comparison], neostigmine/ct [Clinical Trial], neuromuscular blocking, outcome assessment, outpatient care, preschool child, propofol, prospective study, pyridostigmine/ae [Adverse Drug Reaction], pyridostigmine/cb [Drug Combination], pyridostigmine/ct [Clinical Trial], randomized controlled trial, rash/si [Side Effect], respiration control, rocuronium, rocuronium/ae [Adverse Drug Reaction], rocuronium/cb [Drug Combination], rocuronium/ct [Clinical Trial], sample size, single blind procedure, time to treatment, treatment planning, vomiting/si [Side Effect], xerostomia/si [Side Effect]}
}

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