Definition of the best prediction criteria of the time domain signal-averaged electrocardiogram for serious arrhythmic events in the postinfarction period. The Cardiac Arrhythmia Suppression Trial/Signal-Averaged Electrocardiogram (CAST/SAECG) Substudy Investigators. El-Sherif, N., Denes, P., Katz, R., Capone, R., Mitchell, L., Carlson, M., & Reynolds-Haertle, R. j-ACC, 25(4):908--14, 1995.
bibtex   
@Article{RSM:El-95,
  author =       "N. El-Sherif and P. Denes and R. Katz and R. Capone
                 and L.B. Mitchell and M. Carlson and R.
                 Reynolds-Haertle",
  title =        "Definition of the best prediction criteria of the time
                 domain signal-averaged electrocardiogram for serious
                 arrhythmic events in the postinfarction period. The
                 Cardiac Arrhythmia Suppression Trial/Signal-Averaged
                 Electrocardiogram ({CAST}/{SAECG}) Substudy
                 Investigators.",
  journal =      j-ACC,
  year =         "1995",
  volume =       "25",
  number =       "4",
  pages =        "908--14",
  robnote =      "RESULTS. During an average (+/- SD) follow-up of 10.3
                 +/- 3.2 months, 45 patients had a serious arrhythmic
                 event (nonfatal ventricular tachycardia or sudden
                 cardiac arrhythmic death). A Cox regression analysis
                 with only the six signal-averaged ECG variables
                 indicated that the filtered QRS duration at 40 Hz > or
                 = 120 ms (QRSD-40 Hz) at a cutpoint > or = 120 ms was
                 the most predictive criterion of arrhythmic events. In
                 a regression analysis that included all clinical,
                 Holter and ejection fraction variables, a QRSD- 40 Hz >
                 or = 120 ms was the most significant predictor (p <
                 0.0001). The positive, negative and total predictive
                 accuracy and odds ratio for QRSD-40 Hz > or = 120 ms
                 were 17\%, 98\%, 88\% and 8.4, respectively, and improved
                 to 32\%, 97\%, 94\% and 16.7, respectively, after
                 combination with ejection fraction < or = 40\% and
                 complex ventricular arrhythmias on the Holter
                 recording. CONCLUSIONS. The signal- averaged ECG
                 predicts serious arrhythmic events in the first year
                 after infarction better than do clinical, ejection
                 fraction and ventricular arrhythmia variables, and
                 QRSD-40 Hz > or = 120 ms provides the best predictive
                 criterion in this clinical setting.",
}
Downloads: 0