Definition of the best prediction criteria of the time domain signal-averaged electrocardiogram for serious arrhythmic events in the postinfarction period. The Cardiac Arrhythmia Suppression Trial/Signal-Averaged Electrocardiogram (CAST/SAECG) Substudy Investigators. El-Sherif, N., Denes, P., Katz, R., Capone, R., Mitchell, L., Carlson, M., & Reynolds-Haertle, R. j-ACC, 25(4):908--14, 1995. bibtex @Article{RSM:El-95,
author = "N. El-Sherif and P. Denes and R. Katz and R. Capone
and L.B. Mitchell and M. Carlson and R.
Reynolds-Haertle",
title = "Definition of the best prediction criteria of the time
domain signal-averaged electrocardiogram for serious
arrhythmic events in the postinfarction period. The
Cardiac Arrhythmia Suppression Trial/Signal-Averaged
Electrocardiogram ({CAST}/{SAECG}) Substudy
Investigators.",
journal = j-ACC,
year = "1995",
volume = "25",
number = "4",
pages = "908--14",
robnote = "RESULTS. During an average (+/- SD) follow-up of 10.3
+/- 3.2 months, 45 patients had a serious arrhythmic
event (nonfatal ventricular tachycardia or sudden
cardiac arrhythmic death). A Cox regression analysis
with only the six signal-averaged ECG variables
indicated that the filtered QRS duration at 40 Hz > or
= 120 ms (QRSD-40 Hz) at a cutpoint > or = 120 ms was
the most predictive criterion of arrhythmic events. In
a regression analysis that included all clinical,
Holter and ejection fraction variables, a QRSD- 40 Hz >
or = 120 ms was the most significant predictor (p <
0.0001). The positive, negative and total predictive
accuracy and odds ratio for QRSD-40 Hz > or = 120 ms
were 17\%, 98\%, 88\% and 8.4, respectively, and improved
to 32\%, 97\%, 94\% and 16.7, respectively, after
combination with ejection fraction < or = 40\% and
complex ventricular arrhythmias on the Holter
recording. CONCLUSIONS. The signal- averaged ECG
predicts serious arrhythmic events in the first year
after infarction better than do clinical, ejection
fraction and ventricular arrhythmia variables, and
QRSD-40 Hz > or = 120 ms provides the best predictive
criterion in this clinical setting.",
}
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{"_id":"SxAaR7y3YsQPXWxnC","bibbaseid":"elsherif-denes-katz-capone-mitchell-carlson-reynoldshaertle-definitionofthebestpredictioncriteriaofthetimedomainsignalaveragedelectrocardiogramforseriousarrhythmiceventsinthepostinfarctionperiodthecardiacarrhythmiasuppressiontrialsignalaveragedelectrocardiogramcastsaecgsubstudyinvestigators-1995","downloads":0,"creationDate":"2016-07-01T21:38:32.688Z","title":"Definition of the best prediction criteria of the time domain signal-averaged electrocardiogram for serious arrhythmic events in the postinfarction period. The Cardiac Arrhythmia Suppression Trial/Signal-Averaged Electrocardiogram (CAST/SAECG) Substudy Investigators.","author_short":["El-Sherif, N.","Denes, P.","Katz, R.","Capone, R.","Mitchell, L.","Carlson, M.","Reynolds-Haertle, R."],"year":1995,"bibtype":"article","biburl":"http://www.sci.utah.edu/~macleod/Bibtex/biglit.bib","bibdata":{"bibtype":"article","type":"article","author":[{"firstnames":["N."],"propositions":[],"lastnames":["El-Sherif"],"suffixes":[]},{"firstnames":["P."],"propositions":[],"lastnames":["Denes"],"suffixes":[]},{"firstnames":["R."],"propositions":[],"lastnames":["Katz"],"suffixes":[]},{"firstnames":["R."],"propositions":[],"lastnames":["Capone"],"suffixes":[]},{"firstnames":["L.B."],"propositions":[],"lastnames":["Mitchell"],"suffixes":[]},{"firstnames":["M."],"propositions":[],"lastnames":["Carlson"],"suffixes":[]},{"firstnames":["R."],"propositions":[],"lastnames":["Reynolds-Haertle"],"suffixes":[]}],"title":"Definition of the best prediction criteria of the time domain signal-averaged electrocardiogram for serious arrhythmic events in the postinfarction period. The Cardiac Arrhythmia Suppression Trial/Signal-Averaged Electrocardiogram (CAST/SAECG) Substudy Investigators.","journal":"j-ACC","year":"1995","volume":"25","number":"4","pages":"908--14","robnote":"RESULTS. During an average (+/- SD) follow-up of 10.3 +/- 3.2 months, 45 patients had a serious arrhythmic event (nonfatal ventricular tachycardia or sudden cardiac arrhythmic death). A Cox regression analysis with only the six signal-averaged ECG variables indicated that the filtered QRS duration at 40 Hz > or = 120 ms (QRSD-40 Hz) at a cutpoint > or = 120 ms was the most predictive criterion of arrhythmic events. In a regression analysis that included all clinical, Holter and ejection fraction variables, a QRSD- 40 Hz > or = 120 ms was the most significant predictor (p < 0.0001). The positive, negative and total predictive accuracy and odds ratio for QRSD-40 Hz > or = 120 ms were 17%, 98%, 88% and 8.4, respectively, and improved to 32%, 97%, 94% and 16.7, respectively, after combination with ejection fraction < or = 40% and complex ventricular arrhythmias on the Holter recording. CONCLUSIONS. The signal- averaged ECG predicts serious arrhythmic events in the first year after infarction better than do clinical, ejection fraction and ventricular arrhythmia variables, and QRSD-40 Hz > or = 120 ms provides the best predictive criterion in this clinical setting.","bibtex":"@Article{RSM:El-95,\n author = \"N. El-Sherif and P. Denes and R. Katz and R. Capone\n and L.B. Mitchell and M. Carlson and R.\n Reynolds-Haertle\",\n title = \"Definition of the best prediction criteria of the time\n domain signal-averaged electrocardiogram for serious\n arrhythmic events in the postinfarction period. The\n Cardiac Arrhythmia Suppression Trial/Signal-Averaged\n Electrocardiogram ({CAST}/{SAECG}) Substudy\n Investigators.\",\n journal = j-ACC,\n year = \"1995\",\n volume = \"25\",\n number = \"4\",\n pages = \"908--14\",\n robnote = \"RESULTS. During an average (+/- SD) follow-up of 10.3\n +/- 3.2 months, 45 patients had a serious arrhythmic\n event (nonfatal ventricular tachycardia or sudden\n cardiac arrhythmic death). A Cox regression analysis\n with only the six signal-averaged ECG variables\n indicated that the filtered QRS duration at 40 Hz > or\n = 120 ms (QRSD-40 Hz) at a cutpoint > or = 120 ms was\n the most predictive criterion of arrhythmic events. In\n a regression analysis that included all clinical,\n Holter and ejection fraction variables, a QRSD- 40 Hz >\n or = 120 ms was the most significant predictor (p <\n 0.0001). The positive, negative and total predictive\n accuracy and odds ratio for QRSD-40 Hz > or = 120 ms\n were 17\\%, 98\\%, 88\\% and 8.4, respectively, and improved\n to 32\\%, 97\\%, 94\\% and 16.7, respectively, after\n combination with ejection fraction < or = 40\\% and\n complex ventricular arrhythmias on the Holter\n recording. CONCLUSIONS. The signal- averaged ECG\n predicts serious arrhythmic events in the first year\n after infarction better than do clinical, ejection\n fraction and ventricular arrhythmia variables, and\n QRSD-40 Hz > or = 120 ms provides the best predictive\n criterion in this clinical setting.\",\n}\n\n","author_short":["El-Sherif, N.","Denes, P.","Katz, R.","Capone, R.","Mitchell, L.","Carlson, M.","Reynolds-Haertle, R."],"key":"RSM:El-95","id":"RSM:El-95","bibbaseid":"elsherif-denes-katz-capone-mitchell-carlson-reynoldshaertle-definitionofthebestpredictioncriteriaofthetimedomainsignalaveragedelectrocardiogramforseriousarrhythmiceventsinthepostinfarctionperiodthecardiacarrhythmiasuppressiontrialsignalaveragedelectrocardiogramcastsaecgsubstudyinvestigators-1995","role":"author","urls":{},"downloads":0,"html":""},"search_terms":["definition","best","prediction","criteria","time","domain","signal","averaged","electrocardiogram","serious","arrhythmic","events","postinfarction","period","cardiac","arrhythmia","suppression","trial","signal","averaged","electrocardiogram","cast","saecg","substudy","investigators","el-sherif","denes","katz","capone","mitchell","carlson","reynolds-haertle"],"keywords":[],"authorIDs":[],"dataSources":["5HG3Kp8zRwDd7FotB"]}