Evaluation of tomosynthesis elastography in a breast-mimicking phantom. Engelken, Jan, F., Sack, I., Klatt, D., Fischer, T., Fallenberg, Maria, E., Bick, U., & Diekmann, F. Eur J Radiol, 81(9):2169--2173, Sep, 2012. Paper doi abstract bibtex To evaluate whether measurement of strain under static compression in tomosynthesis of a breast-mimicking phantom can be used to distinguish tumor-simulating lesions of different elasticities and to compare the results to values predicted by rheometric analysis as well as results of ultrasound elastography.We prepared three soft breast-mimicking phantoms containing simulated tumors of different elasticities. The phantoms were imaged using a wide angle tomosynthesis system with increasing compression settings ranging from 0 N to 105 N in steps of 15 N. Strain of the inclusions was measured in two planes using a commercially available mammography workstation. The elasticity of the phantom matrix and inclusion material was determined by rheometric analysis. Ultrasound elastography of the inclusions was performed using two different ultrasound elastography algorithms.Strain at maximal compression was 24.4%/24.5% in plane 1/plane 2, respectively, for the soft inclusion, 19.6%/16.9% for the intermediate inclusion, and 6.0%/10.2% for the firm inclusion. The strain ratios predicted by rheometrical testing were 0.41, 0.83 and 1.26 for the soft, intermediate, and firm inclusions, respectively. The strain ratios obtained for the soft, intermediate, and firm inclusions were 0.72�0.13, 1.02�0.21 and 2.67�1.70, respectively for tomosynthesis elastography, 0.91, 1.64 and 2.07, respectively, for ultrasound tissue strain imaging, and 0.97, 2.06 and 2.37, respectively, for ultrasound real-time elastography.Differentiation of tumor-simulating inclusions by elasticity in a breast mimicking phantom may be possible by measuring strain in tomosynthesis. This method may be useful for assessing elasticity of breast lesions tomosynthesis of the breast.
@article{ Engelken2012,
author = {Engelken, Florian Jan and Sack, Ingolf and Klatt, Dieter and Fischer,
Thomas and Fallenberg, Eva Maria and Bick, Ulrich and Diekmann, Felix},
title = {Evaluation of tomosynthesis elastography in a breast-mimicking phantom.},
journal = {Eur J Radiol},
year = {2012},
volume = {81},
pages = {2169--2173},
number = {9},
month = {Sep},
abstract = {To evaluate whether measurement of strain under static compression
in tomosynthesis of a breast-mimicking phantom can be used to distinguish
tumor-simulating lesions of different elasticities and to compare
the results to values predicted by rheometric analysis as well as
results of ultrasound elastography.We prepared three soft breast-mimicking
phantoms containing simulated tumors of different elasticities. The
phantoms were imaged using a wide angle tomosynthesis system with
increasing compression settings ranging from 0 N to 105 N in steps
of 15 N. Strain of the inclusions was measured in two planes using
a commercially available mammography workstation. The elasticity
of the phantom matrix and inclusion material was determined by rheometric
analysis. Ultrasound elastography of the inclusions was performed
using two different ultrasound elastography algorithms.Strain at
maximal compression was 24.4%/24.5% in plane 1/plane 2, respectively,
for the soft inclusion, 19.6%/16.9% for the intermediate inclusion,
and 6.0%/10.2% for the firm inclusion. The strain ratios predicted
by rheometrical testing were 0.41, 0.83 and 1.26 for the soft, intermediate,
and firm inclusions, respectively. The strain ratios obtained for
the soft, intermediate, and firm inclusions were 0.72�0.13, 1.02�0.21
and 2.67�1.70, respectively for tomosynthesis elastography, 0.91,
1.64 and 2.07, respectively, for ultrasound tissue strain imaging,
and 0.97, 2.06 and 2.37, respectively, for ultrasound real-time elastography.Differentiation
of tumor-simulating inclusions by elasticity in a breast mimicking
phantom may be possible by measuring strain in tomosynthesis. This
method may be useful for assessing elasticity of breast lesions tomosynthesis
of the breast.},
doi = {10.1016/j.ejrad.2011.06.033},
institution = {Department of Radiology, Charit� Universit�tsmedizin Berlin, Charit�platz
1, 10117 Berlin, Germany. florian.engelken@charite.de},
keywords = {Breast Neoplasms, physiopathology/ultrasonography; Elastic Modulus;
Elasticity Imaging Techniques, instrumentation/methods; Female; Humans;
Phantoms, Imaging; Reproducibility of Results; Sensitivity and Specificity;
Ultrasonography, Mammary, instrumentation/methods},
language = {eng},
medline-pst = {ppublish},
owner = {Heiko},
pii = {S0720-048X(11)00574-2},
pmid = {21724357},
timestamp = {2013.07.26},
url = {http://dx.doi.org/10.1016/j.ejrad.2011.06.033}
}
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{"_id":{"_str":"5208fc7ea9e4b91d2f000198"},"__v":0,"authorIDs":[],"author_short":["Engelken","Jan, F.","Sack, I.","Klatt, D.","Fischer, T.","Fallenberg","Maria, E.","Bick, U.","Diekmann, F."],"bibbaseid":"engelken-jan-sack-klatt-fischer-fallenberg-maria-bick-diekmann-evaluationoftomosynthesiselastographyinabreastmimickingphantom-2012","bibdata":{"html":"<div class=\"bibbase_paper\">\n\n\n<span class=\"bibbase_paper_titleauthoryear\">\n\t<span class=\"bibbase_paper_title\"><a name=\"Engelken2012\"> </a>Evaluation of tomosynthesis elastography in a breast-mimicking phantom..</span>\n\t<span class=\"bibbase_paper_author\">\nEngelken; Jan, F.; Sack, I.; Klatt, D.; Fischer, T.; Fallenberg; Maria, E.; Bick, U.; and Diekmann, F.</span>\n\t<!-- <span class=\"bibbase_paper_year\">2012</span>. -->\n</span>\n\n\n\n<i>Eur J Radiol</i>,\n\n81(9):2169--2173.\n\nSep 2012.\n\n\n\n\n<br class=\"bibbase_paper_content\"/>\n\n<span class=\"bibbase_paper_content\">\n \n \n <!-- <i -->\n <!-- onclick=\"javascript:log_download('engelken-jan-sack-klatt-fischer-fallenberg-maria-bick-diekmann-evaluationoftomosynthesiselastographyinabreastmimickingphantom-2012', 'http://dx.doi.org/10.1016/j.ejrad.2011.06.033')\">DEBUG -->\n <!-- </i> -->\n\n <a href=\"http://dx.doi.org/10.1016/j.ejrad.2011.06.033\"\n onclick=\"javascript:log_download('engelken-jan-sack-klatt-fischer-fallenberg-maria-bick-diekmann-evaluationoftomosynthesiselastographyinabreastmimickingphantom-2012', 'http://dx.doi.org/10.1016/j.ejrad.2011.06.033')\">\n <img src=\"http://www.bibbase.org/img/filetypes/blank.png\"\n\t alt=\"Evaluation of tomosynthesis elastography in a breast-mimicking phantom. [.033]\" \n\t class=\"bibbase_icon\"\n\t style=\"width: 24px; height: 24px; border: 0px; vertical-align: text-top\" ><span class=\"bibbase_icon_text\">Paper</span></a> \n \n \n <a href=\"javascript:showBib('Engelken2012')\">\n <img src=\"http://www.bibbase.org/img/filetypes/bib.png\" \n\t alt=\"Evaluation of tomosynthesis elastography in a breast-mimicking phantom. [bib]\" \n\t class=\"bibbase_icon\"\n\t style=\"width: 24px; height: 24px; border: 0px; vertical-align: text-top\"><span class=\"bibbase_icon_text\">Bibtex</span></a>\n \n \n\n \n \n \n \n \n\n \n <a class=\"bibbase_abstract_link\" href=\"javascript:showAbstract('Engelken2012')\">Abstract</a>\n \n \n</span>\n\n<!-- -->\n<!-- <div id=\"abstract_Engelken2012\"> -->\n<!-- To evaluate whether measurement of strain under static compression in tomosynthesis of a breast-mimicking phantom can be used to distinguish tumor-simulating lesions of different elasticities and to compare the results to values predicted by rheometric analysis as well as results of ultrasound elastography.We prepared three soft breast-mimicking phantoms containing simulated tumors of different elasticities. The phantoms were imaged using a wide angle tomosynthesis system with increasing compression settings ranging from 0 N to 105 N in steps of 15 N. Strain of the inclusions was measured in two planes using a commercially available mammography workstation. The elasticity of the phantom matrix and inclusion material was determined by rheometric analysis. Ultrasound elastography of the inclusions was performed using two different ultrasound elastography algorithms.Strain at maximal compression was 24.4%/24.5% in plane 1/plane 2, respectively, for the soft inclusion, 19.6%/16.9% for the intermediate inclusion, and 6.0%/10.2% for the firm inclusion. The strain ratios predicted by rheometrical testing were 0.41, 0.83 and 1.26 for the soft, intermediate, and firm inclusions, respectively. The strain ratios obtained for the soft, intermediate, and firm inclusions were 0.72�0.13, 1.02�0.21 and 2.67�1.70, respectively for tomosynthesis elastography, 0.91, 1.64 and 2.07, respectively, for ultrasound tissue strain imaging, and 0.97, 2.06 and 2.37, respectively, for ultrasound real-time elastography.Differentiation of tumor-simulating inclusions by elasticity in a breast mimicking phantom may be possible by measuring strain in tomosynthesis. This method may be useful for assessing elasticity of breast lesions tomosynthesis of the breast. -->\n<!-- </div> -->\n<!-- -->\n\n</div>\n","downloads":0,"abstract":"To evaluate whether measurement of strain under static compression in tomosynthesis of a breast-mimicking phantom can be used to distinguish tumor-simulating lesions of different elasticities and to compare the results to values predicted by rheometric analysis as well as results of ultrasound elastography.We prepared three soft breast-mimicking phantoms containing simulated tumors of different elasticities. The phantoms were imaged using a wide angle tomosynthesis system with increasing compression settings ranging from 0 N to 105 N in steps of 15 N. Strain of the inclusions was measured in two planes using a commercially available mammography workstation. The elasticity of the phantom matrix and inclusion material was determined by rheometric analysis. Ultrasound elastography of the inclusions was performed using two different ultrasound elastography algorithms.Strain at maximal compression was 24.4%/24.5% in plane 1/plane 2, respectively, for the soft inclusion, 19.6%/16.9% for the intermediate inclusion, and 6.0%/10.2% for the firm inclusion. The strain ratios predicted by rheometrical testing were 0.41, 0.83 and 1.26 for the soft, intermediate, and firm inclusions, respectively. The strain ratios obtained for the soft, intermediate, and firm inclusions were 0.72�0.13, 1.02�0.21 and 2.67�1.70, respectively for tomosynthesis elastography, 0.91, 1.64 and 2.07, respectively, for ultrasound tissue strain imaging, and 0.97, 2.06 and 2.37, respectively, for ultrasound real-time elastography.Differentiation of tumor-simulating inclusions by elasticity in a breast mimicking phantom may be possible by measuring strain in tomosynthesis. This method may be useful for assessing elasticity of breast lesions tomosynthesis of the breast.","author":["Engelken","Jan, Florian","Sack, Ingolf","Klatt, Dieter","Fischer, Thomas","Fallenberg","Maria, Eva","Bick, Ulrich","Diekmann, Felix"],"author_short":["Engelken","Jan, F.","Sack, I.","Klatt, D.","Fischer, T.","Fallenberg","Maria, E.","Bick, U.","Diekmann, F."],"bibtex":"@article{ Engelken2012,\n author = {Engelken, Florian Jan and Sack, Ingolf and Klatt, Dieter and Fischer,\r\n\tThomas and Fallenberg, Eva Maria and Bick, Ulrich and Diekmann, Felix},\n title = {Evaluation of tomosynthesis elastography in a breast-mimicking phantom.},\n journal = {Eur J Radiol},\n year = {2012},\n volume = {81},\n pages = {2169--2173},\n number = {9},\n month = {Sep},\n abstract = {To evaluate whether measurement of strain under static compression\r\n\tin tomosynthesis of a breast-mimicking phantom can be used to distinguish\r\n\ttumor-simulating lesions of different elasticities and to compare\r\n\tthe results to values predicted by rheometric analysis as well as\r\n\tresults of ultrasound elastography.We prepared three soft breast-mimicking\r\n\tphantoms containing simulated tumors of different elasticities. The\r\n\tphantoms were imaged using a wide angle tomosynthesis system with\r\n\tincreasing compression settings ranging from 0 N to 105 N in steps\r\n\tof 15 N. Strain of the inclusions was measured in two planes using\r\n\ta commercially available mammography workstation. The elasticity\r\n\tof the phantom matrix and inclusion material was determined by rheometric\r\n\tanalysis. Ultrasound elastography of the inclusions was performed\r\n\tusing two different ultrasound elastography algorithms.Strain at\r\n\tmaximal compression was 24.4%/24.5% in plane 1/plane 2, respectively,\r\n\tfor the soft inclusion, 19.6%/16.9% for the intermediate inclusion,\r\n\tand 6.0%/10.2% for the firm inclusion. The strain ratios predicted\r\n\tby rheometrical testing were 0.41, 0.83 and 1.26 for the soft, intermediate,\r\n\tand firm inclusions, respectively. The strain ratios obtained for\r\n\tthe soft, intermediate, and firm inclusions were 0.72�0.13, 1.02�0.21\r\n\tand 2.67�1.70, respectively for tomosynthesis elastography, 0.91,\r\n\t1.64 and 2.07, respectively, for ultrasound tissue strain imaging,\r\n\tand 0.97, 2.06 and 2.37, respectively, for ultrasound real-time elastography.Differentiation\r\n\tof tumor-simulating inclusions by elasticity in a breast mimicking\r\n\tphantom may be possible by measuring strain in tomosynthesis. This\r\n\tmethod may be useful for assessing elasticity of breast lesions tomosynthesis\r\n\tof the breast.},\n doi = {10.1016/j.ejrad.2011.06.033},\n institution = {Department of Radiology, Charit� Universit�tsmedizin Berlin, Charit�platz\r\n\t1, 10117 Berlin, Germany. florian.engelken@charite.de},\n keywords = {Breast Neoplasms, physiopathology/ultrasonography; Elastic Modulus;\r\n\tElasticity Imaging Techniques, instrumentation/methods; Female; Humans;\r\n\tPhantoms, Imaging; Reproducibility of Results; Sensitivity and Specificity;\r\n\tUltrasonography, Mammary, instrumentation/methods},\n language = {eng},\n medline-pst = {ppublish},\n owner = {Heiko},\n pii = {S0720-048X(11)00574-2},\n pmid = {21724357},\n timestamp = {2013.07.26},\n url = {http://dx.doi.org/10.1016/j.ejrad.2011.06.033}\n}","bibtype":"article","doi":"10.1016/j.ejrad.2011.06.033","id":"Engelken2012","institution":"Department of Radiology, Charit� Universit�tsmedizin Berlin, Charit�platz 1, 10117 Berlin, Germany. florian.engelken@charite.de","journal":"Eur J Radiol","key":"Engelken2012","keywords":"Breast Neoplasms, physiopathology/ultrasonography; Elastic Modulus; Elasticity Imaging Techniques, instrumentation/methods; Female; Humans; Phantoms, Imaging; Reproducibility of Results; Sensitivity and Specificity; Ultrasonography, Mammary, instrumentation/methods","language":"eng","medline-pst":"ppublish","month":"Sep","number":"9","owner":"Heiko","pages":"2169--2173","pii":"S0720-048X(11)00574-2","pmid":"21724357","timestamp":"2013.07.26","title":"Evaluation of tomosynthesis elastography in a breast-mimicking phantom.","type":"article","url":"http://dx.doi.org/10.1016/j.ejrad.2011.06.033","volume":"81","year":"2012","role":"author","urls":{"Paper":"http://dx.doi.org/10.1016/j.ejrad.2011.06.033"},"bibbaseid":"engelken-jan-sack-klatt-fischer-fallenberg-maria-bick-diekmann-evaluationoftomosynthesiselastographyinabreastmimickingphantom-2012"},"bibtype":"article","biburl":"http://home.arcor.de/teambushido/Literatur.bib","downloads":0,"title":"Evaluation of tomosynthesis elastography in a breast-mimicking phantom.","year":2012,"dataSources":["z828pEjP7GR5ew7B7"]}