HAPLO-ASP: Haplotype Inference Using Answer Set Programming. Erdem, E., Erdem, O., & Ture, F. In Proc. of the 10th International Conference of Logic Programming and Nonmonotonic Reasoning (LPNMR'09), pages 573-578, 2009. Link abstract bibtex Identifying maternal and paternal inheritance is essential to be able to find the set of genes responsible for a particular disease. However, due to technological limitations, we have access to genotype data (genetic makeup of an individual), and determining haplotypes (genetic makeup of the parents) experimentally is a costly and time consuming procedure. With these biological motivations, we study haplotype inference -- determining the haplotypes that form a given set of genotypes -- using Answer Set Programming; we call our approach HAPLO-ASP. This note summarizes the range of problems that can be handled by HAPLO-ASP, and its applicability and effectiveness on real data in comparison with the other existing approaches.
@inproceedings{ DBLP:conf/lpnmr/ErdemET09,
author = {Esra Erdem and Ozan Erdem and Ferhan Ture},
title = {HAPLO-ASP: Haplotype Inference Using Answer Set Programming},
abstract = {Identifying maternal and paternal inheritance is essential to be able to find the set of genes responsible for a particular disease. However, due to technological limitations, we have access to genotype data (genetic makeup of an individual), and determining haplotypes (genetic makeup of the parents) experimentally is a costly and time consuming procedure. With these biological motivations, we study haplotype inference -- determining the haplotypes that form a given set of genotypes -- using Answer Set Programming; we call our approach HAPLO-ASP. This note summarizes the range of problems that can be handled by HAPLO-ASP, and its applicability and effectiveness on real data in comparison with the other existing approaches.},
booktitle = {Proc. of the 10th International Conference of Logic Programming and Nonmonotonic Reasoning (LPNMR'09)},
pages = {573-578},
ee = {http://dx.doi.org/10.1007/978-3-642-04238-6_60} ,
year = {2009}
}
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