USEFULNESS OF INFLUENZA VACCINATION IN THE ELDERLY. Fattalgerman, M., Taillandier, J., Mathieu, D., Bauman, F., & Bizzini, B. Biomedicine & Pharmacotherapy, 45(1):29–32, 1991.
USEFULNESS OF INFLUENZA VACCINATION IN THE ELDERLY [link]Paper  abstract   bibtex   
Since influenza morbidity and mortality are high in the elderly, the usefulness of vaccination has been evaluated. One hundred and twenty-six older persons aged 60-90 yr were given a vaccine consisting of the 3 antigens Singapore, Shanghai and Yamagata, the latter 2 being new antigens. Antibody levels for each of the antigens were determined by ELISA calibrated in HA units prior to and 1 month after vaccination. Before vaccination, antibodies to Shanghai and Singapore antigens were found in practically all sera tested, and antibodies to Yamagata antigen in only 66% of sera. After vaccination, significant levels of antibodies to all 3 antigens were found in all sera tested. Thus, it was observed that influenza vaccination proved to be effective in the elderly. The elderly should be immunized against influenza, since this is a safe and efficacious preventive measure. In addition, vaccination should limit the spreading of influenza in nursing homes.
@article{fattalgerman_usefulness_1991,
	title = {{USEFULNESS} {OF} {INFLUENZA} {VACCINATION} {IN} {THE} {ELDERLY}},
	volume = {45},
	issn = {0753-3322},
	url = {://WOS:A1991FC55800005},
	abstract = {Since influenza morbidity and mortality are high in the elderly, the usefulness of vaccination has been evaluated. One hundred and twenty-six older persons aged 60-90 yr were given a vaccine consisting of the 3 antigens Singapore, Shanghai and Yamagata, the latter 2 being new antigens. Antibody levels for each of the antigens were determined by ELISA calibrated in HA units prior to and 1 month after vaccination. Before vaccination, antibodies to Shanghai and Singapore antigens were found in practically all sera tested, and antibodies to Yamagata antigen in only 66\% of sera. After vaccination, significant levels of antibodies to all 3 antigens were found in all sera tested. Thus, it was observed that influenza vaccination proved to be effective in the elderly. The elderly should be immunized against influenza, since this is a safe and efficacious preventive measure. In addition, vaccination should limit the spreading of influenza in nursing homes.},
	language = {English},
	number = {1},
	journal = {Biomedicine \& Pharmacotherapy},
	author = {Fattalgerman, M. and Taillandier, J. and Mathieu, D. and Bauman, F. and Bizzini, B.},
	year = {1991},
	keywords = {Pharmacology \& Pharmacy, Research \& Experimental Medicine, anticorps, mortality, population, vaccination antigrippale, vieillard},
	pages = {29--32},
}

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