Predictors of Functional Changes in Italian Nursing Home Residents: The U.L.I.S.S.E. Study. Fedecostante, M., Dell'Aquila, G., Eusebi, P., Volpato, S., Zuliani, G., Abete, P., Lattanzio, F., & Cherubini, A. Journal of the American Medical Directors Association, AMDA - The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc, 12, 2015.
abstract   bibtex   
OBJECTIVES: To identify independent predictors of the risk of functional decline in older nursing home (NH) residents. DESIGN: A longitudinal observational study. SETTING: Thirty-one NHs participating in the U.L.I.S.S.E. project, distributed throughout Italy. PARTICIPANTS: All older (>/=65 years) long-term NH residents without complete disability and with at least one follow-up evaluation during the 12-month study period (n = 1263). MEASUREMENTS: All participants underwent a standardized comprehensive evaluation using the Italian version of the Minimum Data Set for NHs. The activities of daily living (ADLs) Long-Form scale was used to evaluate functional status. Facility characteristics were collected using an ad hoc designed questionnaire. RESULTS: Of the NH residents, 40.4% experienced a decline in the ADL during the follow-up. The mixed effect logistic regression model showed that depression (odds ratio [OR] 1.45, confidence interval [CI] 1.16-1.81, P = .005) and the use of antipsychotics (OR 1.30, CI 1.06-1.60, P = .016) were associated with a higher probability of ADL decline, whereas the presence of a geriatrician (OR 0.60, CI 0.41-0.88, P = .015) and a higher than median hour per resident per week of nursing care (OR 0.55, CI 0.37-0.80, P = .006) were associated with a lower risk. CONCLUSIONS: Our findings suggest that preventing functional decline in NH residents might be possible by optimizing the management of depression and by reducing the current high prescription rate of antipsychotics. Moreover, the presence of a geriatrician, associated with an adequate amount of nursing care, seem to be important facilities characteristics to achieve this goal. These findings should be tested in large-scale pragmatic clinical trials.
@article{
 title = {Predictors of Functional Changes in Italian Nursing Home Residents: The U.L.I.S.S.E. Study},
 type = {article},
 year = {2015},
 identifiers = {[object Object]},
 keywords = {Nursing home,antipsychotics,depression,functional decline,geriatrician,nurse},
 month = {12},
 publisher = {AMDA - The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc},
 day = {20},
 city = {Department of Medicine, Geriatrics and Geriatric Emergency Care, IRCCS-INRCA, Ancona, Italy.; Department of Medicine, Geriatrics and Geriatric Emergency Care, IRCCS-INRCA, Ancona, Italy.; Epidemiology Department, Regional Health Authority of Umbria, Perug},
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 created = {2016-08-20T16:55:42.000Z},
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 last_modified = {2017-03-14T09:54:45.334Z},
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 notes = {LR: 20151231; CI: Copyright (c) 2015; JID: 100893243; OTO: NOTNLM; 2015/09/28 [received]; 2015/11/02 [revised]; 2015/11/02 [accepted]; aheadofprint},
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 abstract = {OBJECTIVES: To identify independent predictors of the risk of functional decline in older nursing home (NH) residents. DESIGN: A longitudinal observational study. SETTING: Thirty-one NHs participating in the U.L.I.S.S.E. project, distributed throughout Italy. PARTICIPANTS: All older (>/=65 years) long-term NH residents without complete disability and with at least one follow-up evaluation during the 12-month study period (n = 1263). MEASUREMENTS: All participants underwent a standardized comprehensive evaluation using the Italian version of the Minimum Data Set for NHs. The activities of daily living (ADLs) Long-Form scale was used to evaluate functional status. Facility characteristics were collected using an ad hoc designed questionnaire. RESULTS: Of the NH residents, 40.4% experienced a decline in the ADL during the follow-up. The mixed effect logistic regression model showed that depression (odds ratio [OR] 1.45, confidence interval [CI] 1.16-1.81, P = .005) and the use of antipsychotics (OR 1.30, CI 1.06-1.60, P = .016) were associated with a higher probability of ADL decline, whereas the presence of a geriatrician (OR 0.60, CI 0.41-0.88, P = .015) and a higher than median hour per resident per week of nursing care (OR 0.55, CI 0.37-0.80, P = .006) were associated with a lower risk. CONCLUSIONS: Our findings suggest that preventing functional decline in NH residents might be possible by optimizing the management of depression and by reducing the current high prescription rate of antipsychotics. Moreover, the presence of a geriatrician, associated with an adequate amount of nursing care, seem to be important facilities characteristics to achieve this goal. These findings should be tested in large-scale pragmatic clinical trials.},
 bibtype = {article},
 author = {Fedecostante, M and Dell'Aquila, G and Eusebi, P and Volpato, S and Zuliani, G and Abete, P and Lattanzio, F and Cherubini, A},
 journal = {Journal of the American Medical Directors Association}
}

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