Specificity, flexibility and valence of DNA bonds guide emulsion architecture. Feng, L., Pontani, L., Dreyfus, R., Chaikin, P., & Brujic, J. SOFT MATTER, 9(41):9816-9823, ROYAL SOC CHEMISTRY, 2013.
abstract   bibtex   
The specificity and thermal reversibility of DNA interactions have enabled the self-assembly of crystal structures, self-replicating materials and colloidal molecules. Grafting DNA onto liquid interfaces of emulsions leads to exciting new architectural possibilities due to the mobility of the DNA ligands and the patches they form between bound droplets. Here we show that the size and number of these adhesion patches (valency) can be controlled. Valence 2 leads to flexible polymers of emulsion droplets, while valence above 4 leads to rigid droplet networks. A simple thermodynamic model quantitatively describes the increase in the patch size with droplet radii, DNA concentration and the stiffness of the tether to the sticky-end. The patches are formed between droplets with complementary DNA strands or alternatively with complementary colloidal nanoparticles to mediate DNA binding between droplets. This emulsion system opens the route to directed self-assembly of more complex structures through distinct DNA bonds with varying strengths and controlled valence and flexibility.
@article{
 title = {Specificity, flexibility and valence of DNA bonds guide emulsion architecture},
 type = {article},
 year = {2013},
 identifiers = {[object Object]},
 pages = {9816-9823},
 volume = {9},
 publisher = {ROYAL SOC CHEMISTRY},
 city = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND},
 id = {8902ff74-db1b-327a-ade9-124badf268db},
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 last_modified = {2017-03-14T12:30:08.401Z},
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 abstract = {The specificity and thermal reversibility of DNA interactions have
enabled the self-assembly of crystal structures, self-replicating
materials and colloidal molecules. Grafting DNA onto liquid interfaces
of emulsions leads to exciting new architectural possibilities due to
the mobility of the DNA ligands and the patches they form between bound
droplets. Here we show that the size and number of these adhesion
patches (valency) can be controlled. Valence 2 leads to flexible
polymers of emulsion droplets, while valence above 4 leads to rigid
droplet networks. A simple thermodynamic model quantitatively describes
the increase in the patch size with droplet radii, DNA concentration and
the stiffness of the tether to the sticky-end. The patches are formed
between droplets with complementary DNA strands or alternatively with
complementary colloidal nanoparticles to mediate DNA binding between
droplets. This emulsion system opens the route to directed self-assembly
of more complex structures through distinct DNA bonds with varying
strengths and controlled valence and flexibility.},
 bibtype = {article},
 author = {Feng, Lang and Pontani, Lea-Laetitia and Dreyfus, Remi and Chaikin, Paul and Brujic, Jasna},
 journal = {SOFT MATTER},
 number = {41}
}

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