Hepatocellular carcinoma and occupation in men: a case-control study. Ferrand, J. F., Cenee, S., Laurent-Puig, P., Loriot, M. A., Trinchet, J. C., Degos, F., Bronovicky, J. P., Pelletier, G., & Stucker, I. J Occup Environ Med, 50(2):212–20, February, 2008. abstract bibtex OBJECTIVE: The principal objective of this work was to evaluate the association between the risk of hepatocellular carcinoma (HCC) and various occupations. METHODS: This case-control study, conducted during 2000 to 2003 in four French hospitals, included 125 men younger than 75 years with incident HCC and 142 men as control subjects. RESULTS: An association with HCC was observed for machinery fitters and machine assemblers (odds ratio [OR] = 4.4 [1.0-19.0], eight exposed cases and three exposed controls). A higher percentage of cases than controls were metal machinists (OR = 2.2 [0.8-5.8], 14 exposed cases and 10 exposed controls), although the difference was not statistically significant. These associations were strongest for subjects with duration of employment greater than 20 years. CONCLUSIONS: Our findings suggest an association between metal machining jobs and hepatocellular carcinoma, although we cannot rule out the possibility that it was observed by chance.
@article{ferrand_hepatocellular_2008,
title = {Hepatocellular carcinoma and occupation in men: a case-control study},
volume = {50},
issn = {1536-5948 (ELECTRONIC); 1076-2752 (LINKING)},
shorttitle = {Hepatocellular carcinoma and occupation in men: a case-control study},
abstract = {OBJECTIVE: The principal objective of this work was to evaluate the association between the risk of hepatocellular carcinoma (HCC) and various occupations. METHODS: This case-control study, conducted during 2000 to 2003 in four French hospitals, included 125 men younger than 75 years with incident HCC and 142 men as control subjects. RESULTS: An association with HCC was observed for machinery fitters and machine assemblers (odds ratio [OR] = 4.4 [1.0-19.0], eight exposed cases and three exposed controls). A higher percentage of cases than controls were metal machinists (OR = 2.2 [0.8-5.8], 14 exposed cases and 10 exposed controls), although the difference was not statistically significant. These associations were strongest for subjects with duration of employment greater than 20 years. CONCLUSIONS: Our findings suggest an association between metal machining jobs and hepatocellular carcinoma, although we cannot rule out the possibility that it was observed by chance.},
number = {2},
journal = {J Occup Environ Med},
author = {Ferrand, J. F. and Cenee, S. and Laurent-Puig, P. and Loriot, M. A. and Trinchet, J. C. and Degos, F. and Bronovicky, J. P. and Pelletier, G. and Stucker, I.},
month = feb,
year = {2008},
keywords = {Adult Aged Carcinoma},
pages = {212--20},
}
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