Nanocapsule formation by interfacial polymer deposition following solvent displacement. Fessi, H., Puisieux, F., Devissaguet, J. P., Ammoury, N., & Benita, S. International Journal of Pharmaceutics, 55(1):R1–R4, October, 1989.
Nanocapsule formation by interfacial polymer deposition following solvent displacement [link]Paper  doi  abstract   bibtex   
Indomethacin-loaded nanocapsules were prepared by deposition of poly-(D,L-lactide) polymer at the o/w interface following acetone displacement from the oily nanodroplets. An attempt was made to elucidate the mechanisms of formation in terms of interfacial turbulence between two unequilibrated liquid phases involving flow, diffusion and surface tension decrease (Marangoni effect).
@article{fessi_nanocapsule_1989,
	title = {Nanocapsule formation by interfacial polymer deposition following solvent displacement},
	volume = {55},
	issn = {0378-5173},
	url = {http://www.sciencedirect.com/science/article/pii/0378517389902810},
	doi = {10.1016/0378-5173(89)90281-0},
	abstract = {Indomethacin-loaded nanocapsules were prepared by deposition of poly-(D,L-lactide) polymer at the o/w interface following acetone displacement from the oily nanodroplets. An attempt was made to elucidate the mechanisms of formation in terms of interfacial turbulence between two unequilibrated liquid phases involving flow, diffusion and surface tension decrease (Marangoni effect).},
	language = {en},
	number = {1},
	urldate = {2020-12-15},
	journal = {International Journal of Pharmaceutics},
	author = {Fessi, H. and Puisieux, F. and Devissaguet, J. Ph. and Ammoury, N. and Benita, S.},
	month = oct,
	year = {1989},
	keywords = {Indomethacin, Marangoni effect, Mechanism formation, Nanocapsule, Poly-(-lactide) polymer},
	pages = {R1--R4},
}

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