Mineral crystal thickness in calcified cartilage and subchondral bone in human end-stage knee osteoarthritis and controls. Finnilä, M. A.; Turunen, M.; Kestilä, I.; Folkesson, E.; Ali, N.; Hughes, V.; Isaksson, H.; Tjörnstrand, J.; Önnerfjord, P.; Saarakkala, S.; and Englund, M. Osteoarthritis and Cartilage, 27:S180–S181, April, 2019.
Mineral crystal thickness in calcified cartilage and subchondral bone in human end-stage knee osteoarthritis and controls [link]Paper  doi  abstract   bibtex   
Purpose: Osteochondral tissues are hierarchical materials by nature and are organized along multiple length scales. At the macrostructural level, bone sclerosis and cartilage erosion are well documented events in osteoarthritis (OA), and the same applies for microstructural hyperplasia (increased chondron volume and trabecular size). However, the knowledge of nano-structural changes is much more limited. Therefore, our aim was to quantify mineral crystal thickness with state-of-the-art micro-focus small-angle X-ray scattering (μSAXS) in calcified cartilage and subchondral bone, comparing end-stage knee OA patients with deceased donors without known knee OA.
@article{finnila_mineral_2019,
	title = {Mineral crystal thickness in calcified cartilage and subchondral bone in human end-stage knee osteoarthritis and controls},
	volume = {27},
	issn = {1063-4584, 1522-9653},
	url = {https://www.oarsijournal.com/article/S1063-4584(19)30315-2/abstract},
	doi = {10.1016/j.joca.2019.02.273},
	abstract = {Purpose: Osteochondral tissues are hierarchical materials by nature and are organized
along multiple length scales. At the macrostructural level, bone sclerosis and cartilage
erosion are well documented events in osteoarthritis (OA), and the same applies for
microstructural hyperplasia (increased chondron volume and trabecular size). However,
the knowledge of nano-structural changes is much more limited. Therefore, our aim
was to quantify mineral crystal thickness with state-of-the-art micro-focus small-angle
X-ray scattering (μSAXS) in calcified cartilage and subchondral bone, comparing end-stage
knee OA patients with deceased donors without known knee OA.},
	language = {English},
	urldate = {2019-04-25},
	journal = {Osteoarthritis and Cartilage},
	author = {Finnilä, M. A. and Turunen, M. and Kestilä, I. and Folkesson, E. and Ali, N. and Hughes, V. and Isaksson, H. and Tjörnstrand, J. and Önnerfjord, P. and Saarakkala, S. and Englund, M.},
	month = apr,
	year = {2019},
	pages = {S180--S181}
}
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