@Article{RSM:Fis2005,
  author =       "G. Fischer and B. Pfeifer and M. Seger and C.
                 Hintermuller and F. Hanser and R. Modre and B. Tilg and
                 T. Trieb and C. Kremser and F.X. Roithinger and F.
                 Hintringer",
  title =        "Computationally efficient noninvasive cardiac
                 activation time imaging.",
  journal =      "Methods Inf Med",
  year =         "2005",
  volume =       "44",
  number =       "5",
  pages =        "674--686",
  robnote =      "The objective is the development of a method which
                 performs the computation in a few minutes run time. The
                 computationally most expensive part is the product of
                 the lead field matrix with a matrix containing the
                 source pattern on the cardiac surface. The particular
                 biophysical properties of both matrices are used for
                 speeding up this operation by more than an order of
                 magnitude. A conjugate gradient optimizer was developed
                 using C++ for computing the activation map. The
                 increase in speed with respect to the previously used
                 Fortran 77 implementation was a factor of 30 at a
                 comparable quality of the results. As an additional
                 finding the coupled regularization strategy, originally
                 introduced for saving computation time, also reduced
                 the sensitivity of the method to the choice of the
                 regularization parameter.",
  bibdate =      "Thu Mar 9 21:00:41 2006",
}

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