Effect of rheumatoid arthritis or systemic lupus erythematosus on the risk of first-time acute myocardial infarction. Fischer, L. M., Schlienger, R. G., Matter, C., Jick, H., & Meier, C. R. The American Journal of Cardiology, 93(2):198--200, January, 2004. abstract bibtex We explored the association between diagnosed rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and the risk of developing a first-time acute myocardial infarction (AMI) by conducting a population-based, case-control analysis using data from the United Kingdom-based General Practice Research Database (GPRD). Among 8,688 patients with AMI and 33,329 matched controls, the adjusted odds ratio (ORs) of AMI for subjects with RA was 1.47 (95% confidence interval [CI] 1.23 to 1.76), and in subjects with both RA and diagnosed hyperlipidemia, the OR was 7.12 (95% CI 4.16 to 12.18). The risk associated with SLE was 2.67 (95% CI 1.34 to 5.34). These results underline that RA and SLE increase the risk of AMI.
@article{fischer_effect_2004,
title = {Effect of rheumatoid arthritis or systemic lupus erythematosus on the risk of first-time acute myocardial infarction},
volume = {93},
issn = {0002-9149},
abstract = {We explored the association between diagnosed rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and the risk of developing a first-time acute myocardial infarction (AMI) by conducting a population-based, case-control analysis using data from the United Kingdom-based General Practice Research Database (GPRD). Among 8,688 patients with AMI and 33,329 matched controls, the adjusted odds ratio (ORs) of AMI for subjects with RA was 1.47 (95\% confidence interval [CI] 1.23 to 1.76), and in subjects with both RA and diagnosed hyperlipidemia, the OR was 7.12 (95\% CI 4.16 to 12.18). The risk associated with SLE was 2.67 (95\% CI 1.34 to 5.34). These results underline that RA and SLE increase the risk of AMI.},
language = {eng},
number = {2},
journal = {The American Journal of Cardiology},
author = {Fischer, Lorenz M. and Schlienger, Raymond G. and Matter, Christian and Jick, Hershel and Meier, Christoph R.},
month = jan,
year = {2004},
pmid = {14715346},
keywords = {Aged, Aged, 80 and over, Arthritis, Rheumatoid, Case-Control Studies, Databases, Factual, Female, Great Britain, Humans, Hyperlipidemias, Logistic Models, Lupus Erythematosus, Systemic, Male, Middle Aged, Myocardial Infarction, Odds Ratio, Risk, Risk Factors},
pages = {198--200}
}
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