@article{flavin_lipoxygenase_2007,
	title = {A lipoxygenase inhibitor in breast cancer brain metastases},
	volume = {82},
	issn = {0167-594X},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/17001517},
	doi = {10.1007/s11060-006-9248-4},
	abstract = {The complication of multiple brain metastases in breast cancer patients is a life threatening condition with limited success following standard therapies. The arachidonate lipoxygenase pathway appears to play a role in brain tumor growth as well as inhibition of apoptosis in in-vitro studies. The down regulation of these arachidonate lipoxygenase growth stimulating products therefore appeared to be a worthwhile consideration for testing in brain metastases not responding to standard therapy. Boswellia serrata, a lipoxygenase inhibitor was applied for this inhibition. Multiple brain metastases were successfully reversed using this method in a breast cancer patient who had not shown improvement after standard therapy. The results suggest a potential new area of therapy for breast cancer patients with brain metastases that may be useful as an adjuvant to our standard therapy.},
	number = {1},
	urldate = {2012-03-25},
	journal = {Journal of Neuro-Oncology},
	author = {Flavin, D F},
	month = mar,
	year = {2007},
	pmid = {17001517},
	keywords = {Adult, Arachidonate Lipoxygenases, Boswellia, Brain Neoplasms, Breast Neoplasms, Female, Humans, Lipoxygenase Inhibitors, Phytotherapy, Remission Induction, Treatment Outcome},
	pages = {91--93},
}

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