Cognitive Impairment: Examining the Effect of Marijuana and Tramadol on Albino Rats. F Okoye, C., A., Udeze, C., N., & Nwaogu, H. EC Psychology and Psychiatry, 71:29-35, 2018.
Website abstract bibtex Citation: Chukwuemeka A F Okoye., et al. " Cognitive Impairment: Examining the Effect of Marijuana and Tramadol on Albino Rats " . Abstract This study examined the effects of marijuana and tramadol on cognitive impairment. Eight (8) participants (Albino Rats) formed the sample size of the experiment. They were three months old with a mean age of 3 and standard deviation of .3000, weighing about 300 -350g. The albino rats were bought from a biochemist who owned an animal farm. Data were collected through experiment conducted by the researchers in which the participates were divided into four (4) experimental groups of 1a and 1b, 2a and 2b. Each of these groups were administered a certain level of marijuana and tramadol substance, with 3 ml as low dosage and 5 ml as high dos-age. Radial Arm Maze was used to measure cognitive impairment, which was based on the rat's ability to visit the arms of the maze which contains the reward and ability to enter each arm a single time. The result of the 2-way ANOVA showed a significant effect of marijuana on cognition among albino rats, (f = 5.44, p < .04) and a non-significant effect of tramadol on cognition among albino rats, (f = .08, p < .80). Implications of the findings were highlighted and recommendations were made for further studies. There seems to be an unprecedented rise in the use of psychoactive substance among human all over the world with negative conse-quences on human's cognitive properties. This observation is supported pointers substance misuse which includes hallucination, eupho-ria feelings, disorientation in time and space, irregular dilation of the pupil, increase in heartbeat and pulse rate as well as disturbances in cognitive process such as material retention, memorization etc. More importantly, psychologists hold that humans are information processing animals; therefore the simple S-R paradigm cannot explain why people show a progressive decline in cognitive activities (Craik and Jennings 1992), something must have happened in the information processing domain. These thought compelled with the fact that much of what is written on this subject matter in this milieu is speculative, makes an experimental study on the effect of psychoactive substance on cognitive processes very persuasive. Cognition is the mental action or process of acquiring knowledge and understanding through thought, experience and senses. Cogni-tion encompasses a process such as knowledge, attention, memory and working memory, judgment and evaluation, reasoning and " com-putation " problem solving and decision making, comprehension and production of language.
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title = {Cognitive Impairment: Examining the Effect of Marijuana and Tramadol on Albino Rats},
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year = {2018},
pages = {29-35},
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abstract = {Citation: Chukwuemeka A F Okoye., et al. " Cognitive Impairment: Examining the Effect of Marijuana and Tramadol on Albino Rats " . Abstract This study examined the effects of marijuana and tramadol on cognitive impairment. Eight (8) participants (Albino Rats) formed the sample size of the experiment. They were three months old with a mean age of 3 and standard deviation of .3000, weighing about 300 -350g. The albino rats were bought from a biochemist who owned an animal farm. Data were collected through experiment conducted by the researchers in which the participates were divided into four (4) experimental groups of 1a and 1b, 2a and 2b. Each of these groups were administered a certain level of marijuana and tramadol substance, with 3 ml as low dosage and 5 ml as high dos-age. Radial Arm Maze was used to measure cognitive impairment, which was based on the rat's ability to visit the arms of the maze which contains the reward and ability to enter each arm a single time. The result of the 2-way ANOVA showed a significant effect of marijuana on cognition among albino rats, (f = 5.44, p < .04) and a non-significant effect of tramadol on cognition among albino rats, (f = .08, p < .80). Implications of the findings were highlighted and recommendations were made for further studies. There seems to be an unprecedented rise in the use of psychoactive substance among human all over the world with negative conse-quences on human's cognitive properties. This observation is supported pointers substance misuse which includes hallucination, eupho-ria feelings, disorientation in time and space, irregular dilation of the pupil, increase in heartbeat and pulse rate as well as disturbances in cognitive process such as material retention, memorization etc. More importantly, psychologists hold that humans are information processing animals; therefore the simple S-R paradigm cannot explain why people show a progressive decline in cognitive activities (Craik and Jennings 1992), something must have happened in the information processing domain. These thought compelled with the fact that much of what is written on this subject matter in this milieu is speculative, makes an experimental study on the effect of psychoactive substance on cognitive processes very persuasive. Cognition is the mental action or process of acquiring knowledge and understanding through thought, experience and senses. Cogni-tion encompasses a process such as knowledge, attention, memory and working memory, judgment and evaluation, reasoning and " com-putation " problem solving and decision making, comprehension and production of language.},
bibtype = {article},
author = {F Okoye, Chukwuemeka A and Udeze, Cynthia N and Nwaogu, Henry},
journal = {EC Psychology and Psychiatry}
}
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