Distribution and Sequence of Gonadotropin-Inhibitory Hormone And Its Potential Role As A Molecular Link Between Feeding and Reproductive Systems in the Pekin Duck (Anas Platyrhynchos Domestica). Fraley, G. S., Coombs, E., Gerometta, E., Colton, S., Sharp, P. J., Li, Q., & Clarke, I. J. General and Comparative Endocrinology, 184:103--110, April, 2013.
Distribution and Sequence of Gonadotropin-Inhibitory Hormone And Its Potential Role As A Molecular Link Between Feeding and Reproductive Systems in the Pekin Duck (Anas Platyrhynchos Domestica) [link]Paper  abstract   bibtex   
The reproductive status of adult Pekin drakes is very sensitive to nutritional status. Thus, the purpose of this study was to increase our understanding of the neurobiology underlying the depressive effect of fasting on the secretion of reproductive hormones. It was hypothesized that this effect was mediated by gonadotropin-inhibitory hormone (GnIH). Networks of GnIH fibers were present throughout the diencephalon, and cell bodies were present primarily, in the hypothalamic paraventricular nucleus (PVN). The duck GnIH gene was cloned and sequenced and found to encode GnIH and two GnIH-related peptides (GnIH-RP1, GnIH-RP2) which have a similar identity to those found in other avian species. Intra-cerebroventricular injection of GnIH, but not of GnIH-RP1, depressed plasma LH and stimulated feeding. Fasting for 48 h depressed plasma LH and induced fos expression in about half the population of GnIH-ir neurons. These data suggest that GnIH neurons are mediators between feeding and reproductive systems in Pekin drakes. (C) 2013 Elsevier Inc. All rights reserved.
@article{ fraley_distribution_2013,
  title = {Distribution and Sequence of Gonadotropin-Inhibitory Hormone And Its Potential Role As A Molecular Link Between Feeding and Reproductive Systems in the Pekin Duck (Anas Platyrhynchos Domestica)},
  volume = {184},
  shorttitle = {Distribution and Sequence of Gonadotropin-Inhibitory Hormone And Its Potential Role As A Molecular Link Between Feeding and Reproductive Systems in the Pekin Duck (Anas Platyrhynchos Domestica)},
  url = {http://digitalcommons.hope.edu/faculty_publications/894},
  abstract = {The reproductive status of adult Pekin drakes is very sensitive to nutritional status. Thus, the purpose of this study was to increase our understanding of the neurobiology underlying the depressive effect of fasting on the secretion of reproductive hormones. It was hypothesized that this effect was mediated by gonadotropin-inhibitory hormone ({GnIH}). Networks of {GnIH} fibers were present throughout the diencephalon, and cell bodies were present primarily, in the hypothalamic paraventricular nucleus ({PVN}). The duck {GnIH} gene was cloned and sequenced and found to encode {GnIH} and two {GnIH}-related peptides ({GnIH}-{RP}1, {GnIH}-{RP}2) which have a similar identity to those found in other avian species. Intra-cerebroventricular injection of {GnIH}, but not of {GnIH}-{RP}1, depressed plasma {LH} and stimulated feeding. Fasting for 48 h depressed plasma {LH} and induced fos expression in about half the population of {GnIH}-ir neurons. These data suggest that {GnIH} neurons are mediators between feeding and reproductive systems in Pekin drakes. (C) 2013 Elsevier Inc. All rights reserved.},
  journal = {General and Comparative Endocrinology},
  author = {Fraley, Gregory S. and Coombs, E and Gerometta, E and Colton, S and Sharp, P J. and Li, Q and Clarke, I J.},
  month = {April},
  year = {2013},
  pages = {103--110}
}

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