Optimal Detection of Subtle Gadolinium Leakage in CSF with Heavily T2-Weighted Fluid-Attenuated Inversion Recovery Imaging. Freeze, W. M., Ter Weele, D. N., Palm, W. M., van Hooren, R. W., Hoff, E. I., Jansen, J. F. A., Jacobs, H. I. L., Verhey, F. R., & Backes, W. H. AJNR Am J Neuroradiol, 40(9):1481-1483, 2019. Freeze, W M Ter Weele, D N Palm, W M van Hooren, R W Hoff, E I Jansen, J F A Jacobs, H I L Verhey, F R Backes, W H eng Research Support, Non-U.S. Gov't 2019/08/10 06:00 AJNR Am J Neuroradiol. 2019 Sep;40(9):1481-1483. doi: 10.3174/ajnr.A6145. Epub 2019 Aug 8.
Paper doi abstract bibtex Pericortical enhancement on postcontrast FLAIR images is a marker for subtle leptomeningeal blood-brain barrier leakage. We explored the optimal FLAIR sequence parameters for the detection of low gadolinium concentrations within the CSF. On the basis of phantom experiments and human in vivo data, we showed that detection of subtle pericortical enhancement can be facilitated by using a relatively long TE. Future studies should choose their FLAIR sequence parameters carefully when assessing pericortical enhancement due to subtle blood-brain barrier leakage.
@article{RN222,
author = {Freeze, W. M. and Ter Weele, D. N. and Palm, W. M. and van Hooren, R. W. and Hoff, E. I. and Jansen, J. F. A. and Jacobs, H. I. L. and Verhey, F. R. and Backes, W. H.},
title = {Optimal Detection of Subtle Gadolinium Leakage in CSF with Heavily T2-Weighted Fluid-Attenuated Inversion Recovery Imaging},
journal = {AJNR Am J Neuroradiol},
volume = {40},
number = {9},
pages = {1481-1483},
note = {Freeze, W M
Ter Weele, D N
Palm, W M
van Hooren, R W
Hoff, E I
Jansen, J F A
Jacobs, H I L
Verhey, F R
Backes, W H
eng
Research Support, Non-U.S. Gov't
2019/08/10 06:00
AJNR Am J Neuroradiol. 2019 Sep;40(9):1481-1483. doi: 10.3174/ajnr.A6145. Epub 2019 Aug 8.},
abstract = {Pericortical enhancement on postcontrast FLAIR images is a marker for subtle leptomeningeal blood-brain barrier leakage. We explored the optimal FLAIR sequence parameters for the detection of low gadolinium concentrations within the CSF. On the basis of phantom experiments and human in vivo data, we showed that detection of subtle pericortical enhancement can be facilitated by using a relatively long TE. Future studies should choose their FLAIR sequence parameters carefully when assessing pericortical enhancement due to subtle blood-brain barrier leakage.},
ISSN = {1936-959X (Electronic)
0195-6108 (Linking)},
DOI = {10.3174/ajnr.A6145},
url = {http://www.ncbi.nlm.nih.gov/pubmed/31395665
http://www.ajnr.org/content/40/9/1481
http://www.ajnr.org/content/40/9/1481.long},
year = {2019},
type = {Journal Article}
}
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