@article{
 title = {Diffusion-weighted magnetic resonance imaging of head and neck squamous cell carcinomas},
 type = {article},
 year = {2008},
 identifiers = {[object Object]},
 keywords = {Diffusion-weighted imaging,Head and neck cancer,Magnetic resonance imaging,Squamous cell carcinoma},
 volume = {68},
 id = {7f6571de-b6b7-348c-9661-a53187ce055a},
 created = {2017-04-06T18:59:17.169Z},
 file_attached = {false},
 profile_id = {9a3985e4-fc59-37eb-ab82-25e7ae4e5771},
 last_modified = {2017-04-06T18:59:17.169Z},
 read = {false},
 starred = {false},
 authored = {true},
 confirmed = {false},
 hidden = {false},
 abstract = {Objective: To evaluate whether diffusion-weighted imaging (DWI) is a reliable technique to quantify microstructural differences between head and neck squamous cell carcinomas (SCC) and tumour-free soft tissue. Materials and methods: DWI was obtained from 20 patients with histologically proven, untreated head and neck SCC. DWI was acquired using a diffusion-weighted, navigated echo-planar imaging sequence with a maximum b-value of 800 s/mm2. For an objective assessment of image quality, the signal-to-noise ratio (SNR) was calculated. Microstructural differences between vital tumour tissue and tumour-free soft tissue were quantified by calculating the apparent-diffusion-coefficients (ADC) on a pixel by pixel method. Results: Echo-planar DWI provided good image quality in all patients (mean SNR 18.4). The mean ADC of SCC, (0.64 ± 0.28 × 10-3 mm2/s), was significantly (P < 0.0001) lower than that of the tumour-free soft tissue, (2.51 ± 0.82 × 10-3 mm2/s). Conclusion: DWI is a reliable diagnostic tool to quantify the microstructural differences between vital tumour tissue and tumour-free soft tissue in patients with head and neck SCC. © 2007 Elsevier Ireland Ltd. All rights reserved.},
 bibtype = {article},
 author = {Friedrich, K.M. and Matzek, W. and Gentzsch, S. and Sulzbacher, I. and Czerny, C. and Herneth, A.M.},
 journal = {European Journal of Radiology},
 number = {3}
}

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Materials and methods: DWI was obtained from 20 patients with histologically proven, untreated head and neck SCC. DWI was acquired using a diffusion-weighted, navigated echo-planar imaging sequence with a maximum b-value of 800 s/mm2. For an objective assessment of image quality, the signal-to-noise ratio (SNR) was calculated. Microstructural differences between vital tumour tissue and tumour-free soft tissue were quantified by calculating the apparent-diffusion-coefficients (ADC) on a pixel by pixel method. Results: Echo-planar DWI provided good image quality in all patients (mean SNR 18.4). The mean ADC of SCC, (0.64 ± 0.28 × 10-3 mm2/s), was significantly (P < 0.0001) lower than that of the tumour-free soft tissue, (2.51 ± 0.82 × 10-3 mm2/s). Conclusion: DWI is a reliable diagnostic tool to quantify the microstructural differences between vital tumour tissue and tumour-free soft tissue in patients with head and neck SCC. © 2007 Elsevier Ireland Ltd. All rights reserved.","bibtype":"article","author":"Friedrich, K.M. and Matzek, W. and Gentzsch, S. and Sulzbacher, I. and Czerny, C. and Herneth, A.M.","journal":"European Journal of Radiology","number":"3","bibtex":"@article{\n title = {Diffusion-weighted magnetic resonance imaging of head and neck squamous cell carcinomas},\n type = {article},\n year = {2008},\n identifiers = {[object Object]},\n keywords = {Diffusion-weighted imaging,Head and neck cancer,Magnetic resonance imaging,Squamous cell carcinoma},\n volume = {68},\n id = {7f6571de-b6b7-348c-9661-a53187ce055a},\n created = {2017-04-06T18:59:17.169Z},\n file_attached = {false},\n profile_id = {9a3985e4-fc59-37eb-ab82-25e7ae4e5771},\n last_modified = {2017-04-06T18:59:17.169Z},\n read = {false},\n starred = {false},\n authored = {true},\n confirmed = {false},\n hidden = {false},\n abstract = {Objective: To evaluate whether diffusion-weighted imaging (DWI) is a reliable technique to quantify microstructural differences between head and neck squamous cell carcinomas (SCC) and tumour-free soft tissue. Materials and methods: DWI was obtained from 20 patients with histologically proven, untreated head and neck SCC. DWI was acquired using a diffusion-weighted, navigated echo-planar imaging sequence with a maximum b-value of 800 s/mm2. For an objective assessment of image quality, the signal-to-noise ratio (SNR) was calculated. Microstructural differences between vital tumour tissue and tumour-free soft tissue were quantified by calculating the apparent-diffusion-coefficients (ADC) on a pixel by pixel method. Results: Echo-planar DWI provided good image quality in all patients (mean SNR 18.4). The mean ADC of SCC, (0.64 ± 0.28 × 10-3 mm2/s), was significantly (P < 0.0001) lower than that of the tumour-free soft tissue, (2.51 ± 0.82 × 10-3 mm2/s). Conclusion: DWI is a reliable diagnostic tool to quantify the microstructural differences between vital tumour tissue and tumour-free soft tissue in patients with head and neck SCC. © 2007 Elsevier Ireland Ltd. All rights reserved.},\n bibtype = {article},\n author = {Friedrich, K.M. and Matzek, W. and Gentzsch, S. and Sulzbacher, I. and Czerny, C. and Herneth, A.M.},\n journal = {European Journal of Radiology},\n number = {3}\n}","author_short":["Friedrich, K.","Matzek, W.","Gentzsch, S.","Sulzbacher, I.","Czerny, C.","Herneth, A."],"bibbaseid":"friedrich-matzek-gentzsch-sulzbacher-czerny-herneth-diffusionweightedmagneticresonanceimagingofheadandnecksquamouscellcarcinomas-2008","role":"author","urls":{},"keyword":["Diffusion-weighted imaging","Head and neck cancer","Magnetic resonance imaging","Squamous cell carcinoma"],"downloads":0},"search_terms":["diffusion","weighted","magnetic","resonance","imaging","head","neck","squamous","cell","carcinomas","friedrich","matzek","gentzsch","sulzbacher","czerny","herneth"],"keywords":["diffusion-weighted imaging","head and neck cancer","magnetic resonance imaging","squamous cell carcinoma"],"authorIDs":["5904e0d85ed15afd59000014"]}