Treatment of Inflamed Pterygium and Pinguecula with Topical Indomethacin 0.1% Solution. Frucht-Pery, J. M. D., Solomon, A. M. D., Siganos, C. S. M. D., Shvartzenberg, T. M. D., Richard, C. M. D., & Trinquand, C. M. D. Cornea, 16(1):42–47, January, 1997. abstract bibtex Purpose. To evaluate the effect of topical indomethacin 0.1% on signs and symptoms in inflamed pterygium and pinguecula. Methods. Fifty-one consecutive patients who had inflamed pterygium (n = 32) or pinguecula (n = 19) were studied in a randomized, double-masked, controlled way. Objective signs (conjunctival congestion, redness, edema, and staining of cornea) and subjective complaints (photophobia, pain, foreign-body sensation, discomfort, and tearing) were evaluated and scored. In addition, we evaluated total signs, total symptoms, and total score. Group I (n = 25) received topical indomethacin 0.1% solution and group 2 (n = 26) received a placebo six times daily for 3 days, then four times daily for 11 days. Patients were examined before and at days 3, 7, and 14 after the treatment began. Results. In group 1 at day 3, the scores of total signs, total symptoms, and total score decreased (p = 0.001), and they further decreased after 14 days (p = 0.02 to p = 0.05). In group 2 at day 3 these parameters also significantly decreased (p = 0.01 to p = 0.02), but no further improvement occurred after 14 days. Comparing groups I and 2 revealed a decrease in scores in group 1 for total signs, total symptoms, and total score at days 3, 7, and 14 (p = 0.03 to p = 0.002) except for total signs after 14 days (p = NS). All the patients reported mild stinging for \textless1 min after administration of the drops. Conclusions. This study indicates that topical indomethacin solution 0.1% is a useful treatment for inflamed pterygium and pinguecula, (C) Lippincott-Raven Publishers.
@article{frucht-pery_treatment_1997,
title = {Treatment of {Inflamed} {Pterygium} and {Pinguecula} with {Topical} {Indomethacin} 0.1\% {Solution}},
volume = {16},
issn = {0277-3740},
abstract = {Purpose. To evaluate the effect of topical indomethacin 0.1\% on signs and symptoms in inflamed pterygium and pinguecula. Methods. Fifty-one consecutive patients who had inflamed pterygium (n = 32) or pinguecula (n = 19) were studied in a randomized, double-masked, controlled way. Objective signs (conjunctival congestion, redness, edema, and staining of cornea) and subjective complaints (photophobia, pain, foreign-body sensation, discomfort, and tearing) were evaluated and scored. In addition, we evaluated total signs, total symptoms, and total score. Group I (n = 25) received topical indomethacin 0.1\% solution and group 2 (n = 26) received a placebo six times daily for 3 days, then four times daily for 11 days. Patients were examined before and at days 3, 7, and 14 after the treatment began. Results. In group 1 at day 3, the scores of total signs, total symptoms, and total score decreased (p = 0.001), and they further decreased after 14 days (p = 0.02 to p = 0.05). In group 2 at day 3 these parameters also significantly decreased (p = 0.01 to p = 0.02), but no further improvement occurred after 14 days. Comparing groups I and 2 revealed a decrease in scores in group 1 for total signs, total symptoms, and total score at days 3, 7, and 14 (p = 0.03 to p = 0.002) except for total signs after 14 days (p = NS). All the patients reported mild stinging for {\textless}1 min after administration of the drops. Conclusions. This study indicates that topical indomethacin solution 0.1\% is a useful treatment for inflamed pterygium and pinguecula, (C) Lippincott-Raven Publishers.},
language = {English.},
number = {1},
journal = {Cornea},
author = {Frucht-Pery, Joseph M. D. and Solomon, Abraham M. D. and Siganos, Charalambos S. M. D. and Shvartzenberg, Tikva M. D. and Richard, Christine M. D. and Trinquand, Claude M. D.},
month = jan,
year = {1997},
keywords = {Inflammation, Pinguecula, Pterygium, Topical indomethacin},
pages = {42--47},
}
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{"_id":"9B8BrK7PZhrKs7yFN","bibbaseid":"fruchtpery-solomon-siganos-shvartzenberg-richard-trinquand-treatmentofinflamedpterygiumandpingueculawithtopicalindomethacin01solution-1997","author_short":["Frucht-Pery, J. M. D.","Solomon, A. M. D.","Siganos, C. S. M. D.","Shvartzenberg, T. M. D.","Richard, C. M. D.","Trinquand, C. M. D."],"bibdata":{"bibtype":"article","type":"article","title":"Treatment of Inflamed Pterygium and Pinguecula with Topical Indomethacin 0.1% Solution","volume":"16","issn":"0277-3740","abstract":"Purpose. To evaluate the effect of topical indomethacin 0.1% on signs and symptoms in inflamed pterygium and pinguecula. Methods. Fifty-one consecutive patients who had inflamed pterygium (n = 32) or pinguecula (n = 19) were studied in a randomized, double-masked, controlled way. Objective signs (conjunctival congestion, redness, edema, and staining of cornea) and subjective complaints (photophobia, pain, foreign-body sensation, discomfort, and tearing) were evaluated and scored. In addition, we evaluated total signs, total symptoms, and total score. Group I (n = 25) received topical indomethacin 0.1% solution and group 2 (n = 26) received a placebo six times daily for 3 days, then four times daily for 11 days. Patients were examined before and at days 3, 7, and 14 after the treatment began. Results. In group 1 at day 3, the scores of total signs, total symptoms, and total score decreased (p = 0.001), and they further decreased after 14 days (p = 0.02 to p = 0.05). In group 2 at day 3 these parameters also significantly decreased (p = 0.01 to p = 0.02), but no further improvement occurred after 14 days. Comparing groups I and 2 revealed a decrease in scores in group 1 for total signs, total symptoms, and total score at days 3, 7, and 14 (p = 0.03 to p = 0.002) except for total signs after 14 days (p = NS). All the patients reported mild stinging for \\textless1 min after administration of the drops. Conclusions. This study indicates that topical indomethacin solution 0.1% is a useful treatment for inflamed pterygium and pinguecula, (C) Lippincott-Raven Publishers.","language":"English.","number":"1","journal":"Cornea","author":[{"propositions":[],"lastnames":["Frucht-Pery"],"firstnames":["Joseph","M.","D."],"suffixes":[]},{"propositions":[],"lastnames":["Solomon"],"firstnames":["Abraham","M.","D."],"suffixes":[]},{"propositions":[],"lastnames":["Siganos"],"firstnames":["Charalambos","S.","M.","D."],"suffixes":[]},{"propositions":[],"lastnames":["Shvartzenberg"],"firstnames":["Tikva","M.","D."],"suffixes":[]},{"propositions":[],"lastnames":["Richard"],"firstnames":["Christine","M.","D."],"suffixes":[]},{"propositions":[],"lastnames":["Trinquand"],"firstnames":["Claude","M.","D."],"suffixes":[]}],"month":"January","year":"1997","keywords":"Inflammation, Pinguecula, Pterygium, Topical indomethacin","pages":"42–47","bibtex":"@article{frucht-pery_treatment_1997,\n\ttitle = {Treatment of {Inflamed} {Pterygium} and {Pinguecula} with {Topical} {Indomethacin} 0.1\\% {Solution}},\n\tvolume = {16},\n\tissn = {0277-3740},\n\tabstract = {Purpose. To evaluate the effect of topical indomethacin 0.1\\% on signs and symptoms in inflamed pterygium and pinguecula. Methods. Fifty-one consecutive patients who had inflamed pterygium (n = 32) or pinguecula (n = 19) were studied in a randomized, double-masked, controlled way. Objective signs (conjunctival congestion, redness, edema, and staining of cornea) and subjective complaints (photophobia, pain, foreign-body sensation, discomfort, and tearing) were evaluated and scored. In addition, we evaluated total signs, total symptoms, and total score. Group I (n = 25) received topical indomethacin 0.1\\% solution and group 2 (n = 26) received a placebo six times daily for 3 days, then four times daily for 11 days. Patients were examined before and at days 3, 7, and 14 after the treatment began. Results. In group 1 at day 3, the scores of total signs, total symptoms, and total score decreased (p = 0.001), and they further decreased after 14 days (p = 0.02 to p = 0.05). In group 2 at day 3 these parameters also significantly decreased (p = 0.01 to p = 0.02), but no further improvement occurred after 14 days. Comparing groups I and 2 revealed a decrease in scores in group 1 for total signs, total symptoms, and total score at days 3, 7, and 14 (p = 0.03 to p = 0.002) except for total signs after 14 days (p = NS). All the patients reported mild stinging for {\\textless}1 min after administration of the drops. Conclusions. This study indicates that topical indomethacin solution 0.1\\% is a useful treatment for inflamed pterygium and pinguecula, (C) Lippincott-Raven Publishers.},\n\tlanguage = {English.},\n\tnumber = {1},\n\tjournal = {Cornea},\n\tauthor = {Frucht-Pery, Joseph M. D. and Solomon, Abraham M. D. and Siganos, Charalambos S. M. D. and Shvartzenberg, Tikva M. D. and Richard, Christine M. D. and Trinquand, Claude M. D.},\n\tmonth = jan,\n\tyear = {1997},\n\tkeywords = {Inflammation, Pinguecula, Pterygium, Topical indomethacin},\n\tpages = {42--47},\n}\n\n","author_short":["Frucht-Pery, J. M. D.","Solomon, A. M. D.","Siganos, C. S. M. D.","Shvartzenberg, T. M. D.","Richard, C. M. D.","Trinquand, C. M. 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