Tamoxifen with or without Breast Irradiation in Women 50 Years of Age or Older with Early Breast Cancer. Fyles, A. W., McCready, D. R., Manchul, L. A., Trudeau, M. E., Merante, P., Pintilie, M., Weir, L. M., & Olivotto, I. A. New England Journal of Medicine, 351(10):963--970, 2004. ![Tamoxifen with or without Breast Irradiation in Women 50 Years of Age or Older with Early Breast Cancer [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex In most women with breast cancer, breast-conserving surgery plus local radiotherapy reduces the risk of recurrence in the ipsilateral breast and results in long-term survival similar to that after mastectomy.1–4 Adjuvant treatment with tamoxifen also reduces the risk of local relapse.5,6 Since mammographic screening is capable of detecting relatively small tumors and salvage therapy is successful in many women who have a relapse in the breast,3,7 there is interest in identifying patients at low risk who could avoid radiotherapy. They are likely to have a small tumor and negative axillary nodes.8 Postmenopausal patients have a lower risk . . .
@article{fyles_tamoxifen_2004,
title = {Tamoxifen with or without {Breast} {Irradiation} in {Women} 50 {Years} of {Age} or {Older} with {Early} {Breast} {Cancer}},
volume = {351},
issn = {0028-4793},
url = {http://www.nejm.org/doi/full/10.1056/NEJMoa040595},
doi = {10.1056/NEJMoa040595},
abstract = {In most women with breast cancer, breast-conserving surgery plus local radiotherapy reduces the risk of recurrence in the ipsilateral breast and results in long-term survival similar to that after mastectomy.1–4 Adjuvant treatment with tamoxifen also reduces the risk of local relapse.5,6 Since mammographic screening is capable of detecting relatively small tumors and salvage therapy is successful in many women who have a relapse in the breast,3,7 there is interest in identifying patients at low risk who could avoid radiotherapy. They are likely to have a small tumor and negative axillary nodes.8 Postmenopausal patients have a lower risk . . .},
number = {10},
urldate = {2013-04-19},
journal = {New England Journal of Medicine},
author = {Fyles, Anthony W. and McCready, David R. and Manchul, Lee A. and Trudeau, Maureen E. and Merante, Patricia and Pintilie, Melania and Weir, Lorna M. and Olivotto, Ivo A.},
year = {2004},
pmid = {15342804},
pages = {963--970},
file = {Full Text PDF:files/38441/Fyles et al. - 2004 - Tamoxifen with or without Breast Irradiation in Wo.pdf:application/pdf}
}
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