Joule heating effects on particle immobilization in insulator-based dielectrophoretic devices. Gallo-Villanueva, R. C., Sano, M. B., Lapizco-Encinas, B. H., & Davalos, R. V. Electrophoresis, 35(2-3):352-61, 2014. 1522-2683 Gallo-Villanueva, Roberto C Sano, Michael B Lapizco-Encinas, Blanca H Davalos, Rafael V R21 CA173092/CA/NCI NIH HHS/United States 5R21 CA173092-01/CA/NCI NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Germany 2013/09/05 Electrophoresis. 2014 Feb;35(2-3):352-61. doi: 10.1002/elps.201300171. Epub 2013 Oct 10.doi abstract bibtex In this work, the temperature effects due to Joule heating obtained by application of a direct current electric potential were investigated for a microchannel with cylindrical insulating posts employed for insulator-based dielectrophoresis. The conductivity of the suspending medium, the local electric field, and the gradient of the squared electric field, which directly affect the magnitude of the dielectrophoretic force exerted on particles, were computationally simulated employing COMSOL Multiphysics. It was observed that a temperature gradient is formed along the microchannel, which redistributes the conductivity of the suspending medium leading to an increase of the dielectrophoretic force toward the inlet of the channel while decreasing toward the outlet. Experimental results are in good agreement with simulations on the particle-trapping zones anticipated. This study demonstrates the importance of considering Joule heating effects when designing insulator-based dielectrophoresis systems.
@article{RN199,
author = {Gallo-Villanueva, R. C. and Sano, M. B. and Lapizco-Encinas, B. H. and Davalos, R. V.},
title = {Joule heating effects on particle immobilization in insulator-based dielectrophoretic devices},
journal = {Electrophoresis},
volume = {35},
number = {2-3},
pages = {352-61},
note = {1522-2683
Gallo-Villanueva, Roberto C
Sano, Michael B
Lapizco-Encinas, Blanca H
Davalos, Rafael V
R21 CA173092/CA/NCI NIH HHS/United States
5R21 CA173092-01/CA/NCI NIH HHS/United States
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Germany
2013/09/05
Electrophoresis. 2014 Feb;35(2-3):352-61. doi: 10.1002/elps.201300171. Epub 2013 Oct 10.},
abstract = {In this work, the temperature effects due to Joule heating obtained by application of a direct current electric potential were investigated for a microchannel with cylindrical insulating posts employed for insulator-based dielectrophoresis. The conductivity of the suspending medium, the local electric field, and the gradient of the squared electric field, which directly affect the magnitude of the dielectrophoretic force exerted on particles, were computationally simulated employing COMSOL Multiphysics. It was observed that a temperature gradient is formed along the microchannel, which redistributes the conductivity of the suspending medium leading to an increase of the dielectrophoretic force toward the inlet of the channel while decreasing toward the outlet. Experimental results are in good agreement with simulations on the particle-trapping zones anticipated. This study demonstrates the importance of considering Joule heating effects when designing insulator-based dielectrophoresis systems.},
keywords = {Electric Conductivity
Electrophoresis/*instrumentation
Finite Element Analysis
*Hot Temperature
Kinetics
Microfluidic Analytical Techniques/*instrumentation
Microspheres
Dielectrophoresis
Electrokinetic
Joule heating
Microchannel},
ISSN = {0173-0835 (Print)
0173-0835},
DOI = {10.1002/elps.201300171},
year = {2014},
type = {Journal Article}
}
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