Systems and methods for high-throughput radiation biodosimetry. Garty, G., Brenner, D. J., Randers-Pehrson, G., Yao, Y. L., Simaan, N., Salerno, A., Bhatla, A., Zhang, J., Lyulko, O. V., & Dutta, A. October 2010. ![Systems and methods for high-throughput radiation biodosimetry [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper abstract bibtex Systems and methods for high-throughput radiation biodosimetry are disclosed herein. In some embodiments, a high-throughput methods of analyzing a population for radiation exposure can include, in various possible sequences: marking a first capillary designed to retain a first sample from the population with a first identifier; transporting a plurality of samples to a biodosimetry system; inputting the samples into the biodosimetry system; centrifuging the plurality of samples including the first sample wherein each sample can be retained in a capillary and the first sample can be retained in the first capillary; transferring the plurality of capillaries including the first capillary from the centrifuge to a cutting device using a robotic device; cutting the first capillary; reading the first identifier; transferring at least one portion of the first sample from the first capillary to a well in an array, wherein the array can include one or more filters in a multi-well plate; correlating the first identifier to a location of the array that includes the at least one portion of the first sample; one or more cycles of biological processing, which can include addition of a reagent and/or incubation of a selected temperature such as, for example, 37° C., 4° C., room temperature, and the like; sealing the array; positioning the array adjacent to an imaging element; focusing the imaging element; capturing an image of the first sample in the array; and analyzing the image to determine whether the first sample indicates a level of radiation exposure exceeding a predetermined threshold.
@patent{garty_systems_2010,
title = {Systems and methods for high-throughput radiation biodosimetry},
url = {https://patents.google.com/patent/US7822249B2/en},
abstract = {Systems and methods for high-throughput radiation biodosimetry are disclosed herein. In some embodiments, a high-throughput methods of analyzing a population for radiation exposure can include, in various possible sequences: marking a first capillary designed to retain a first sample from the population with a first identifier; transporting a plurality of samples to a biodosimetry system; inputting the samples into the biodosimetry system; centrifuging the plurality of samples including the first sample wherein each sample can be retained in a capillary and the first sample can be retained in the first capillary; transferring the plurality of capillaries including the first capillary from the centrifuge to a cutting device using a robotic device; cutting the first capillary; reading the first identifier; transferring at least one portion of the first sample from the first capillary to a well in an array, wherein the array can include one or more filters in a multi-well plate; correlating the first identifier to a location of the array that includes the at least one portion of the first sample; one or more cycles of biological processing, which can include addition of a reagent and/or incubation of a selected temperature such as, for example, 37° C., 4° C., room temperature, and the like; sealing the array; positioning the array adjacent to an imaging element; focusing the imaging element; capturing an image of the first sample in the array; and analyzing the image to determine whether the first sample indicates a level of radiation exposure exceeding a predetermined threshold.},
nationality = {US},
language = {en},
assignee = {Columbia University of New York},
number = {US7822249B2},
urldate = {2018-10-29TZ},
author = {Garty, Guy and Brenner, David J. and Randers-Pehrson, Gerhard and Yao, Y. Lawrence and Simaan, Nabil and Salerno, Alessio and Bhatla, Anubha and Zhang, Jian and Lyulko, Oleksandra V. and Dutta, Aparajita},
month = oct,
year = {2010},
keywords = {capillary, embodiments, image, plurality, sample}
}
Downloads: 0
{"_id":"SkN8RgjWuARC4s84Q","bibbaseid":"garty-brenner-randerspehrson-yao-simaan-salerno-bhatla-zhang-etal-systemsandmethodsforhighthroughputradiationbiodosimetry-2010","downloads":0,"creationDate":"2018-10-29T22:19:59.491Z","title":"Systems and methods for high-throughput radiation biodosimetry","author_short":["Garty, G.","Brenner, D. J.","Randers-Pehrson, G.","Yao, Y. L.","Simaan, N.","Salerno, A.","Bhatla, A.","Zhang, J.","Lyulko, O. V.","Dutta, A."],"year":2010,"bibtype":"patent","biburl":"https://bibbase.org/zotero/aorekhov","bibdata":{"bibtype":"patent","type":"patent","title":"Systems and methods for high-throughput radiation biodosimetry","url":"https://patents.google.com/patent/US7822249B2/en","abstract":"Systems and methods for high-throughput radiation biodosimetry are disclosed herein. In some embodiments, a high-throughput methods of analyzing a population for radiation exposure can include, in various possible sequences: marking a first capillary designed to retain a first sample from the population with a first identifier; transporting a plurality of samples to a biodosimetry system; inputting the samples into the biodosimetry system; centrifuging the plurality of samples including the first sample wherein each sample can be retained in a capillary and the first sample can be retained in the first capillary; transferring the plurality of capillaries including the first capillary from the centrifuge to a cutting device using a robotic device; cutting the first capillary; reading the first identifier; transferring at least one portion of the first sample from the first capillary to a well in an array, wherein the array can include one or more filters in a multi-well plate; correlating the first identifier to a location of the array that includes the at least one portion of the first sample; one or more cycles of biological processing, which can include addition of a reagent and/or incubation of a selected temperature such as, for example, 37° C., 4° C., room temperature, and the like; sealing the array; positioning the array adjacent to an imaging element; focusing the imaging element; capturing an image of the first sample in the array; and analyzing the image to determine whether the first sample indicates a level of radiation exposure exceeding a predetermined threshold.","nationality":"US","language":"en","assignee":"Columbia University of New York","number":"US7822249B2","urldate":"2018-10-29TZ","author":[{"propositions":[],"lastnames":["Garty"],"firstnames":["Guy"],"suffixes":[]},{"propositions":[],"lastnames":["Brenner"],"firstnames":["David","J."],"suffixes":[]},{"propositions":[],"lastnames":["Randers-Pehrson"],"firstnames":["Gerhard"],"suffixes":[]},{"propositions":[],"lastnames":["Yao"],"firstnames":["Y.","Lawrence"],"suffixes":[]},{"propositions":[],"lastnames":["Simaan"],"firstnames":["Nabil"],"suffixes":[]},{"propositions":[],"lastnames":["Salerno"],"firstnames":["Alessio"],"suffixes":[]},{"propositions":[],"lastnames":["Bhatla"],"firstnames":["Anubha"],"suffixes":[]},{"propositions":[],"lastnames":["Zhang"],"firstnames":["Jian"],"suffixes":[]},{"propositions":[],"lastnames":["Lyulko"],"firstnames":["Oleksandra","V."],"suffixes":[]},{"propositions":[],"lastnames":["Dutta"],"firstnames":["Aparajita"],"suffixes":[]}],"month":"October","year":"2010","keywords":"capillary, embodiments, image, plurality, sample","bibtex":"@patent{garty_systems_2010,\n\ttitle = {Systems and methods for high-throughput radiation biodosimetry},\n\turl = {https://patents.google.com/patent/US7822249B2/en},\n\tabstract = {Systems and methods for high-throughput radiation biodosimetry are disclosed herein. In some embodiments, a high-throughput methods of analyzing a population for radiation exposure can include, in various possible sequences: marking a first capillary designed to retain a first sample from the population with a first identifier; transporting a plurality of samples to a biodosimetry system; inputting the samples into the biodosimetry system; centrifuging the plurality of samples including the first sample wherein each sample can be retained in a capillary and the first sample can be retained in the first capillary; transferring the plurality of capillaries including the first capillary from the centrifuge to a cutting device using a robotic device; cutting the first capillary; reading the first identifier; transferring at least one portion of the first sample from the first capillary to a well in an array, wherein the array can include one or more filters in a multi-well plate; correlating the first identifier to a location of the array that includes the at least one portion of the first sample; one or more cycles of biological processing, which can include addition of a reagent and/or incubation of a selected temperature such as, for example, 37° C., 4° C., room temperature, and the like; sealing the array; positioning the array adjacent to an imaging element; focusing the imaging element; capturing an image of the first sample in the array; and analyzing the image to determine whether the first sample indicates a level of radiation exposure exceeding a predetermined threshold.},\n\tnationality = {US},\n\tlanguage = {en},\n\tassignee = {Columbia University of New York},\n\tnumber = {US7822249B2},\n\turldate = {2018-10-29TZ},\n\tauthor = {Garty, Guy and Brenner, David J. and Randers-Pehrson, Gerhard and Yao, Y. Lawrence and Simaan, Nabil and Salerno, Alessio and Bhatla, Anubha and Zhang, Jian and Lyulko, Oleksandra V. and Dutta, Aparajita},\n\tmonth = oct,\n\tyear = {2010},\n\tkeywords = {capillary, embodiments, image, plurality, sample}\n}\n\n","author_short":["Garty, G.","Brenner, D. J.","Randers-Pehrson, G.","Yao, Y. L.","Simaan, N.","Salerno, A.","Bhatla, A.","Zhang, J.","Lyulko, O. V.","Dutta, A."],"key":"garty_systems_2010","id":"garty_systems_2010","bibbaseid":"garty-brenner-randerspehrson-yao-simaan-salerno-bhatla-zhang-etal-systemsandmethodsforhighthroughputradiationbiodosimetry-2010","role":"author","urls":{"Paper":"https://patents.google.com/patent/US7822249B2/en"},"keyword":["capillary","embodiments","image","plurality","sample"],"downloads":0},"search_terms":["systems","methods","high","throughput","radiation","biodosimetry","garty","brenner","randers-pehrson","yao","simaan","salerno","bhatla","zhang","lyulko","dutta"],"keywords":["capillary","embodiments","image","plurality","sample"],"authorIDs":[],"dataSources":["Q5cy5ZnQZvoGxZ7DT"]}