Particle tracking by repetitive phase-shift interferometric super resolution microscopy. Gdor, I., Wang, X., Daddysman, M., Yifat, Y., Wilton, R., Hereld, M., Noirot-Gros, M., & Scherer, N. F. Optics Letters, 43(12):2819, jun, 2018.
Particle tracking by repetitive phase-shift interferometric super resolution microscopy [link]Paper  doi  abstract   bibtex   
Accurate and rapid particle tracking is essential for addressing many research problems in single molecule and cellular biophysics and colloidal soft condensed matter physics. We developed a novel three-dimensional interferometric fluorescent particle tracking approach that does not require any sample scanning. By periodically shifting the interferometer phase, the information stored in the interference pattern of the emitted light allows localizing particles positions with nanometer resolution. This tracking protocol was demonstrated by measuring a known trajectory of a fluorescent bead with sub-5 nm axial localization error at 5 Hz. The interferometric microscopy was used to track the RecA protein in Bacillus subtilis bacteria to demonstrate its compatibility with biological systems.
@article{Itay2018,
abstract = {Accurate and rapid particle tracking is essential for addressing many research problems in single molecule and cellular biophysics and colloidal soft condensed matter physics. We developed a novel three-dimensional interferometric fluorescent particle tracking approach that does not require any sample scanning. By periodically shifting the interferometer phase, the information stored in the interference pattern of the emitted light allows localizing particles positions with nanometer resolution. This tracking protocol was demonstrated by measuring a known trajectory of a fluorescent bead with sub-5 nm axial localization error at 5 Hz. The interferometric microscopy was used to track the RecA protein in Bacillus subtilis bacteria to demonstrate its compatibility with biological systems.},
author = {Gdor, Itay and Wang, Xiaolei and Daddysman, Matthew and Yifat, Yuval and Wilton, Rosemarie and Hereld, Mark and Noirot-Gros, Marie-Fran{\c{c}}oise and Scherer, Norbert F.},
doi = {10.1364/OL.43.002819},
issn = {0146-9592},
journal = {Optics Letters},
month = {jun},
number = {12},
pages = {2819},
pmid = {29905697},
title = {{Particle tracking by repetitive phase-shift interferometric super resolution microscopy}},
url = {https://opg.optica.org/abstract.cfm?URI=ol-43-12-2819},
volume = {43},
year = {2018}
}

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