GeneTrail 3: advanced high-throughput enrichment analysis. Gerstner, N., Kehl, T., Lenhof, K., Müller, A., Mayer, C., Eckhart, L., Grammes, N. L., Diener, C., Hart, M., Hahn, O., Walter, J., Wyss-Coray, T., Meese, E., Keller, A., & Lenhof, H. Nucleic Acids Research, 05, 2020.
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We present GeneTrail 3, a major extension of our web service GeneTrail that offers rich functionality for the identification, analysis, and visualization of deregulated biological processes. Our web service provides a comprehensive collection of biological processes and signaling pathways for 12 model organisms that can be analyzed with a powerful framework for enrichment and network analysis of transcriptomic, miRNomic, proteomic, and genomic data sets. Moreover, GeneTrail offers novel workflows for the analysis of epigenetic marks, time series experiments, and single cell data. We demonstrate the capabilities of our web service in two case-studies, which highlight that GeneTrail is well equipped for uncovering complex molecular mechanisms. GeneTrail is freely accessible at: http://genetrail.bioinf.uni-sb.de.
@Article{10.1093/nar/gkaa306,
    author       = {Gerstner, Nico and Kehl, Tim and Lenhof, Kerstin and Müller, Anne and Mayer, Carolin and Eckhart, Lea and Grammes, Nadja Liddy and Diener, Caroline and Hart, Martin and Hahn, Oliver and Walter, Jörn and Wyss-Coray, Tony and Meese, Eckart and Keller, Andreas and Lenhof, Hans-Peter},
    title        = {GeneTrail 3: advanced high-throughput enrichment analysis},
    journal      = {Nucleic Acids Research},
    year         = {2020},
    month        = {05},
    abstract     = {We present GeneTrail 3, a major extension of our web service GeneTrail that offers rich functionality for the identification, analysis, and visualization of deregulated biological processes. Our web service provides a comprehensive collection of biological processes and signaling pathways for 12 model organisms that can be analyzed with a powerful framework for enrichment and network analysis of transcriptomic, miRNomic, proteomic, and genomic data sets. Moreover, GeneTrail offers novel workflows for the analysis of epigenetic marks, time series experiments, and single cell data. We demonstrate the capabilities of our web service in two case-studies, which highlight that GeneTrail is well equipped for uncovering complex molecular mechanisms. GeneTrail is freely accessible at: http://genetrail.bioinf.uni-sb.de.},
    doi          = {10.1093/nar/gkaa306},
    pii          = {10.1093/nar/gkaa306},
}

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