@article{
 title = {A positive correlation between mercury and oxidative stress-related gene expression (GPX3 and GSTM3) is measured in female Double-crested Cormorant blood},
 type = {article},
 year = {2014},
 identifiers = {[object Object]},
 keywords = {Aquatic birds,Gene expression,Glutathione S-transferases,Glutathione peroxidases,Oxidative stress},
 pages = {1004-1014},
 volume = {23},
 id = {11f81462-e20d-307f-bd2b-be59b2bb0a06},
 created = {2020-05-02T13:04:56.243Z},
 file_attached = {true},
 profile_id = {d529d6d9-691c-3d58-ace4-a53b70b2cd14},
 group_id = {3addd0f7-d578-34d3-be80-24022cc062a1},
 last_modified = {2020-05-02T13:07:08.835Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 folder_uuids = {ac76ddcc-3c0f-4e14-bc4c-bb384747cb49,c81bf04c-0ac3-42b2-b672-1d239f736119},
 private_publication = {false},
 abstract = {Mercury (Hg) is a widespread contaminant that has been shown to induce a wide range of adverse health effects in birds including reproductive, physiological and neurological impairments. Here we explored the relationship between blood total Hg concentrations ([THg]) and oxidative stress gene induction in the aquatic piscivorous Double-crested Cormorants (Phalacrocorax auritus) using a non-lethal technique, i.e., blood gene expression analysis. P. auritus blood was sampled at five sites across the Great Lakes basin, Ontario, Canada and was analyzed for [THg]. To assess cellular stress, the expression of glutathione peroxidases 1 and 3 (GPX1, GPX3), superoxide dismutase 1 (SOD1), heat-shock protein 70 kd-8 (HSP70-8) and glutathione S-transferase μ3 (GSTM3) were measured in whole blood samples using real-time RT-PCR. Results showed a significantly positive correlation between female blood [THg] and both GPX3 and GSTM3 expression. Different levels of oxidative stress experienced by males and females during the breeding season may be influencing the differential oxidative stress responses to blood [THg] observed in this study. Overall, these results suggest that Hg may lead to oxidative stress as some of the cellular stress-related genes were altered in the blood of female P. auritus and that blood gene expression analysis is a successful approach to assess bird health condition. © 2014 Springer Science+Business Media.},
 bibtype = {article},
 author = {Gibson, Laura A. and Lavoie, Raphael A. and Bissegger, Sonja and Campbell, Linda M. and Langlois, Valerie S.},
 journal = {Ecotoxicology},
 number = {6}
}

{"_id":"ovPpcfRtiYmfnotZQ","bibbaseid":"gibson-lavoie-bissegger-campbell-langlois-apositivecorrelationbetweenmercuryandoxidativestressrelatedgeneexpressiongpx3andgstm3ismeasuredinfemaledoublecrestedcormorantblood-2014","authorIDs":[],"author_short":["Gibson, L., A.","Lavoie, R., A.","Bissegger, S.","Campbell, L., M.","Langlois, V., S."],"bibdata":{"title":"A positive correlation between mercury and oxidative stress-related gene expression (GPX3 and GSTM3) is measured in female Double-crested Cormorant blood","type":"article","year":"2014","identifiers":"[object Object]","keywords":"Aquatic birds,Gene expression,Glutathione S-transferases,Glutathione peroxidases,Oxidative stress","pages":"1004-1014","volume":"23","id":"11f81462-e20d-307f-bd2b-be59b2bb0a06","created":"2020-05-02T13:04:56.243Z","file_attached":"true","profile_id":"d529d6d9-691c-3d58-ace4-a53b70b2cd14","group_id":"3addd0f7-d578-34d3-be80-24022cc062a1","last_modified":"2020-05-02T13:07:08.835Z","read":false,"starred":false,"authored":false,"confirmed":"true","hidden":false,"folder_uuids":"ac76ddcc-3c0f-4e14-bc4c-bb384747cb49,c81bf04c-0ac3-42b2-b672-1d239f736119","private_publication":false,"abstract":"Mercury (Hg) is a widespread contaminant that has been shown to induce a wide range of adverse health effects in birds including reproductive, physiological and neurological impairments. Here we explored the relationship between blood total Hg concentrations ([THg]) and oxidative stress gene induction in the aquatic piscivorous Double-crested Cormorants (Phalacrocorax auritus) using a non-lethal technique, i.e., blood gene expression analysis. P. auritus blood was sampled at five sites across the Great Lakes basin, Ontario, Canada and was analyzed for [THg]. To assess cellular stress, the expression of glutathione peroxidases 1 and 3 (GPX1, GPX3), superoxide dismutase 1 (SOD1), heat-shock protein 70 kd-8 (HSP70-8) and glutathione S-transferase μ3 (GSTM3) were measured in whole blood samples using real-time RT-PCR. Results showed a significantly positive correlation between female blood [THg] and both GPX3 and GSTM3 expression. Different levels of oxidative stress experienced by males and females during the breeding season may be influencing the differential oxidative stress responses to blood [THg] observed in this study. Overall, these results suggest that Hg may lead to oxidative stress as some of the cellular stress-related genes were altered in the blood of female P. auritus and that blood gene expression analysis is a successful approach to assess bird health condition. © 2014 Springer Science+Business Media.","bibtype":"article","author":"Gibson, Laura A. and Lavoie, Raphael A. and Bissegger, Sonja and Campbell, Linda M. and Langlois, Valerie S.","journal":"Ecotoxicology","number":"6","bibtex":"@article{\n title = {A positive correlation between mercury and oxidative stress-related gene expression (GPX3 and GSTM3) is measured in female Double-crested Cormorant blood},\n type = {article},\n year = {2014},\n identifiers = {[object Object]},\n keywords = {Aquatic birds,Gene expression,Glutathione S-transferases,Glutathione peroxidases,Oxidative stress},\n pages = {1004-1014},\n volume = {23},\n id = {11f81462-e20d-307f-bd2b-be59b2bb0a06},\n created = {2020-05-02T13:04:56.243Z},\n file_attached = {true},\n profile_id = {d529d6d9-691c-3d58-ace4-a53b70b2cd14},\n group_id = {3addd0f7-d578-34d3-be80-24022cc062a1},\n last_modified = {2020-05-02T13:07:08.835Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n folder_uuids = {ac76ddcc-3c0f-4e14-bc4c-bb384747cb49,c81bf04c-0ac3-42b2-b672-1d239f736119},\n private_publication = {false},\n abstract = {Mercury (Hg) is a widespread contaminant that has been shown to induce a wide range of adverse health effects in birds including reproductive, physiological and neurological impairments. Here we explored the relationship between blood total Hg concentrations ([THg]) and oxidative stress gene induction in the aquatic piscivorous Double-crested Cormorants (Phalacrocorax auritus) using a non-lethal technique, i.e., blood gene expression analysis. P. auritus blood was sampled at five sites across the Great Lakes basin, Ontario, Canada and was analyzed for [THg]. To assess cellular stress, the expression of glutathione peroxidases 1 and 3 (GPX1, GPX3), superoxide dismutase 1 (SOD1), heat-shock protein 70 kd-8 (HSP70-8) and glutathione S-transferase μ3 (GSTM3) were measured in whole blood samples using real-time RT-PCR. Results showed a significantly positive correlation between female blood [THg] and both GPX3 and GSTM3 expression. Different levels of oxidative stress experienced by males and females during the breeding season may be influencing the differential oxidative stress responses to blood [THg] observed in this study. Overall, these results suggest that Hg may lead to oxidative stress as some of the cellular stress-related genes were altered in the blood of female P. auritus and that blood gene expression analysis is a successful approach to assess bird health condition. © 2014 Springer Science+Business Media.},\n bibtype = {article},\n author = {Gibson, Laura A. and Lavoie, Raphael A. and Bissegger, Sonja and Campbell, Linda M. and Langlois, Valerie S.},\n journal = {Ecotoxicology},\n number = {6}\n}","author_short":["Gibson, L., A.","Lavoie, R., A.","Bissegger, S.","Campbell, L., M.","Langlois, V., S."],"bibbaseid":"gibson-lavoie-bissegger-campbell-langlois-apositivecorrelationbetweenmercuryandoxidativestressrelatedgeneexpressiongpx3andgstm3ismeasuredinfemaledoublecrestedcormorantblood-2014","role":"author","urls":{},"keyword":["Aquatic birds","Gene expression","Glutathione S-transferases","Glutathione peroxidases","Oxidative stress"],"downloads":0},"bibtype":"article","creationDate":"2020-12-22T22:02:17.212Z","downloads":0,"keywords":["aquatic birds","gene expression","glutathione s-transferases","glutathione peroxidases","oxidative stress"],"search_terms":["positive","correlation","between","mercury","oxidative","stress","related","gene","expression","gpx3","gstm3","measured","female","double","crested","cormorant","blood","gibson","lavoie","bissegger","campbell","langlois"],"title":"A positive correlation between mercury and oxidative stress-related gene expression (GPX3 and GSTM3) is measured in female Double-crested Cormorant blood","year":2014}