Human whole genome sequencing in South Africa. Glanzmann, B., Jooste, T., Ghoor, S., Gordon, R., Mia, R., Mao, J., Li, H., Charls, P., Douman, C., Kotze, M. J, Peeters, A. V, Loots, G., Esser, M., Tiemessen, C. T, Wilkinson, R. J, Louw, J., Gray, G., Warren, R. M, Möller, M., & Kinnear, C. Scientific Reports, 11(1):606, Nature Research, dec, 2021. ![Human whole genome sequencing in South Africa [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex The advent and evolution of next generation sequencing has considerably impacted genomic research. Until recently, South African researchers were unable to access affordable platforms capable of human whole genome sequencing locally and DNA samples had to be exported. Here we report the whole genome sequences of the first six human DNA samples sequenced and analysed at the South African Medical Research Council's Genomics Centre. We demonstrate that the data obtained is of high quality, with an average sequencing depth of 36.41, and that the output is comparable to data generated internationally on a similar platform. The Genomics Centre creates an environment where African researchers are able to access world class facilities, increasing local capacity to sequence whole genomes as well as store and analyse the data.
@article{Glanzmann2021,
abstract = {The advent and evolution of next generation sequencing has considerably impacted genomic research. Until recently, South African researchers were unable to access affordable platforms capable of human whole genome sequencing locally and DNA samples had to be exported. Here we report the whole genome sequences of the first six human DNA samples sequenced and analysed at the South African Medical Research Council's Genomics Centre. We demonstrate that the data obtained is of high quality, with an average sequencing depth of 36.41, and that the output is comparable to data generated internationally on a similar platform. The Genomics Centre creates an environment where African researchers are able to access world class facilities, increasing local capacity to sequence whole genomes as well as store and analyse the data.},
author = {Glanzmann, Brigitte and Jooste, Tracey and Ghoor, Samira and Gordon, Richard and Mia, Rizwana and Mao, Jun and Li, Hao and Charls, Patrick and Douman, Craig and Kotze, Maritha J and Peeters, Armand V and Loots, Glaudina and Esser, Monika and Tiemessen, Caroline T and Wilkinson, Robert J and Louw, Johan and Gray, Glenda and Warren, Robin M and M{\"{o}}ller, Marlo and Kinnear, Craig},
doi = {10.1038/s41598-020-79794-x},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Glanzmann et al. - 2021 - Human whole genome sequencing in South Africa.pdf:pdf},
issn = {20452322},
journal = {Scientific Reports},
keywords = {Biological techniques,Computational biology and bioinformatics,Diseases,Genetics,OA,fund{\_}not{\_}ack,original},
mendeley-tags = {OA,fund{\_}not{\_}ack,original},
month = {dec},
number = {1},
pages = {606},
pmid = {33436733},
publisher = {Nature Research},
title = {{Human whole genome sequencing in South Africa}},
url = {https://doi.org/10.1038/s41598-020-79794-x},
volume = {11},
year = {2021}
}
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