Prevention of sudden death in adolescent athletes: Incremental diagnostic value and cost-effectiveness of diagnostic tests. Grazioli, G., Sanz de la Garza, M., Vidal, B., Montserrat, S., Sarquella-Brugada, G., Pi, R., Til, L., Gutierrez, J., Brugada, J., & Sitges, M. European Journal of Preventive Cardiology, 24(13):1446–1454, 2017.
doi  abstract   bibtex   
Introduction Pre-participation screening in athletes attempts to reduce the incidence of sudden death during sports by identifying susceptible individuals. The objective of this study was to evaluate the diagnostic capacity of the different pre-participation screening points in adolescent athletes and the cost effectiveness of the programme. Methods Athletes were studied between 12-18 years old. Pre-participation screening included the American Heart Association questionnaire, electrocardiogram, echocardiogram, and stress test. The cost of test was established by the Catalan public health system. Results Of 1650 athletes included, 57% were men and mean age was 15.09 ± 1.82 years. Positive findings were identified as follows: in American Heart Association questionnaire 5.09% of subjects, in electrocardiogram 3.78%, in echocardiogram 4.96%, and in exercise test 1.75%. Six athletes (0.36%) were disqualified from participation and 10 (0.60%) were referred for interventional treatment. Diagnostic capacity was assessed by the area under the curve for detection of diseases that motivated disqualification for sport practice (American Heart Association questionnaire, 0.55; electrocardiogram, 0.72; echocardiogram, 0.88; stress test, 0.57). The cost for each athlete disqualified from the sport for a disease causing sudden death was €45,578. Conclusion The electrocardiogram and echocardiogram were the most useful studies to detect athletes susceptible to sudden death, and the stress test best diagnosed arrhythmias with specific treatment. In our country, pre-participatory screening was cost effective to detect athletes who might experience sudden death in sports.
@article{grazioli_prevention_2017,
	title = {Prevention of sudden death in adolescent athletes: {Incremental} diagnostic value and cost-effectiveness of diagnostic tests},
	volume = {24},
	issn = {2047-4881},
	shorttitle = {Prevention of sudden death in adolescent athletes},
	doi = {10.1177/2047487317713328},
	abstract = {Introduction Pre-participation screening in athletes attempts to reduce the incidence of sudden death during sports by identifying susceptible individuals. The objective of this study was to evaluate the diagnostic capacity of the different pre-participation screening points in adolescent athletes and the cost effectiveness of the programme. Methods Athletes were studied between 12-18 years old. Pre-participation screening included the American Heart Association questionnaire, electrocardiogram, echocardiogram, and stress test. The cost of test was established by the Catalan public health system. Results Of 1650 athletes included, 57\% were men and mean age was 15.09 ± 1.82 years. Positive findings were identified as follows: in American Heart Association questionnaire 5.09\% of subjects, in electrocardiogram 3.78\%, in echocardiogram 4.96\%, and in exercise test 1.75\%. Six athletes (0.36\%) were disqualified from participation and 10 (0.60\%) were referred for interventional treatment. Diagnostic capacity was assessed by the area under the curve for detection of diseases that motivated disqualification for sport practice (American Heart Association questionnaire, 0.55; electrocardiogram, 0.72; echocardiogram, 0.88; stress test, 0.57). The cost for each athlete disqualified from the sport for a disease causing sudden death was €45,578. Conclusion The electrocardiogram and echocardiogram were the most useful studies to detect athletes susceptible to sudden death, and the stress test best diagnosed arrhythmias with specific treatment. In our country, pre-participatory screening was cost effective to detect athletes who might experience sudden death in sports.},
	language = {eng},
	number = {13},
	journal = {European Journal of Preventive Cardiology},
	author = {Grazioli, Gonzalo and Sanz de la Garza, Maria and Vidal, Barbara and Montserrat, Silvia and Sarquella-Brugada, Georgia and Pi, Ramon and Til, Lluis and Gutierrez, Josep and Brugada, Josep and Sitges, Marta},
	year = {2017},
	pmid = {28574282},
	keywords = {Article, Athletes, CAR Sant Cugat, Sudden death, cost-effectiveness, echocardiogram, electrocardiogram, pre-participation screening, stress test},
	pages = {1446--1454},
}

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