Partner services in adults with acute and early HIV infection. Green, N., Hoenigl, M., Chaillon, A., Anderson, C. M., Kosakovsky Pond, S. L., Smith, D. M., & Little, S. J. AIDS (London, England), 31(2):287–293, 2017. doi abstract bibtex BACKGROUND: To examine the yield of HIV partner services provided to persons newly diagnosed with acute and early HIV infection (AEH) in San Diego, United States. DESIGN: Observational cohort study. METHODS: The study investigated the yield (i.e. number of new HIV and AEH diagnoses, genetically linked partnerships and high-risk uninfected partners) of partner services (confidential contact tracing) for individuals with AEH enrolled in the San Diego Primary Infection Resource Consortium 1996-2014. RESULTS: A total of 107 of 574 persons with AEH (19%; i.e. index cases) provided sufficient information to recruit 119 sex partners. Fifty-seven percent of the 119 recruited partners were HIV infected, and 33% of the 119 were newly HIV diagnosed. Among those newly HIV diagnosed, 36% were diagnosed during AEH. There were no significant demographic or behavioral risk differences between HIV-infected and HIV-uninfected recruited partners. Genetic sequences were available for both index cases and partners in 62 partnerships, of which 61% were genetically linked. Partnerships in which both index case and partner enrolled within 30 days were more likely to yield a new HIV diagnosis (P = 0.01) and to be genetically linked (P \textless 0.01). CONCLUSION: Partner services for persons with AEH within 30 days of diagnosis represents an effective tool to find HIV-unaware persons, including those with AEH who are at greatest risk of HIV transmission.
@article{green_partner_2017,
title = {Partner services in adults with acute and early {HIV} infection},
volume = {31},
issn = {1473-5571},
doi = {10.1097/QAD.0000000000001308},
abstract = {BACKGROUND: To examine the yield of HIV partner services provided to persons newly diagnosed with acute and early HIV infection (AEH) in San Diego, United States.
DESIGN: Observational cohort study.
METHODS: The study investigated the yield (i.e. number of new HIV and AEH diagnoses, genetically linked partnerships and high-risk uninfected partners) of partner services (confidential contact tracing) for individuals with AEH enrolled in the San Diego Primary Infection Resource Consortium 1996-2014.
RESULTS: A total of 107 of 574 persons with AEH (19\%; i.e. index cases) provided sufficient information to recruit 119 sex partners. Fifty-seven percent of the 119 recruited partners were HIV infected, and 33\% of the 119 were newly HIV diagnosed. Among those newly HIV diagnosed, 36\% were diagnosed during AEH. There were no significant demographic or behavioral risk differences between HIV-infected and HIV-uninfected recruited partners. Genetic sequences were available for both index cases and partners in 62 partnerships, of which 61\% were genetically linked. Partnerships in which both index case and partner enrolled within 30 days were more likely to yield a new HIV diagnosis (P = 0.01) and to be genetically linked (P {\textless} 0.01).
CONCLUSION: Partner services for persons with AEH within 30 days of diagnosis represents an effective tool to find HIV-unaware persons, including those with AEH who are at greatest risk of HIV transmission.},
language = {eng},
number = {2},
journal = {AIDS (London, England)},
author = {Green, Nella and Hoenigl, Martin and Chaillon, Antoine and Anderson, Christy M. and Kosakovsky Pond, Sergei L. and Smith, Davey M. and Little, Susan J.},
year = {2017},
pmid = {27831950},
pmcid = {PMC5177524},
keywords = {Adolescent, Adult, California, Cohort Studies, Contact Tracing, HIV Infections, Humans, Young Adult},
pages = {287--293},
}
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RESULTS: A total of 107 of 574 persons with AEH (19%; i.e. index cases) provided sufficient information to recruit 119 sex partners. Fifty-seven percent of the 119 recruited partners were HIV infected, and 33% of the 119 were newly HIV diagnosed. Among those newly HIV diagnosed, 36% were diagnosed during AEH. There were no significant demographic or behavioral risk differences between HIV-infected and HIV-uninfected recruited partners. Genetic sequences were available for both index cases and partners in 62 partnerships, of which 61% were genetically linked. Partnerships in which both index case and partner enrolled within 30 days were more likely to yield a new HIV diagnosis (P = 0.01) and to be genetically linked (P \\textless 0.01). CONCLUSION: Partner services for persons with AEH within 30 days of diagnosis represents an effective tool to find HIV-unaware persons, including those with AEH who are at greatest risk of HIV transmission.","language":"eng","number":"2","journal":"AIDS (London, England)","author":[{"propositions":[],"lastnames":["Green"],"firstnames":["Nella"],"suffixes":[]},{"propositions":[],"lastnames":["Hoenigl"],"firstnames":["Martin"],"suffixes":[]},{"propositions":[],"lastnames":["Chaillon"],"firstnames":["Antoine"],"suffixes":[]},{"propositions":[],"lastnames":["Anderson"],"firstnames":["Christy","M."],"suffixes":[]},{"propositions":[],"lastnames":["Kosakovsky","Pond"],"firstnames":["Sergei","L."],"suffixes":[]},{"propositions":[],"lastnames":["Smith"],"firstnames":["Davey","M."],"suffixes":[]},{"propositions":[],"lastnames":["Little"],"firstnames":["Susan","J."],"suffixes":[]}],"year":"2017","pmid":"27831950","pmcid":"PMC5177524","keywords":"Adolescent, Adult, California, Cohort Studies, Contact Tracing, HIV Infections, Humans, Young Adult","pages":"287–293","bibtex":"@article{green_partner_2017,\n\ttitle = {Partner services in adults with acute and early {HIV} infection},\n\tvolume = {31},\n\tissn = {1473-5571},\n\tdoi = {10.1097/QAD.0000000000001308},\n\tabstract = {BACKGROUND: To examine the yield of HIV partner services provided to persons newly diagnosed with acute and early HIV infection (AEH) in San Diego, United States.\nDESIGN: Observational cohort study.\nMETHODS: The study investigated the yield (i.e. number of new HIV and AEH diagnoses, genetically linked partnerships and high-risk uninfected partners) of partner services (confidential contact tracing) for individuals with AEH enrolled in the San Diego Primary Infection Resource Consortium 1996-2014.\nRESULTS: A total of 107 of 574 persons with AEH (19\\%; i.e. index cases) provided sufficient information to recruit 119 sex partners. Fifty-seven percent of the 119 recruited partners were HIV infected, and 33\\% of the 119 were newly HIV diagnosed. Among those newly HIV diagnosed, 36\\% were diagnosed during AEH. There were no significant demographic or behavioral risk differences between HIV-infected and HIV-uninfected recruited partners. Genetic sequences were available for both index cases and partners in 62 partnerships, of which 61\\% were genetically linked. Partnerships in which both index case and partner enrolled within 30 days were more likely to yield a new HIV diagnosis (P = 0.01) and to be genetically linked (P {\\textless} 0.01).\nCONCLUSION: Partner services for persons with AEH within 30 days of diagnosis represents an effective tool to find HIV-unaware persons, including those with AEH who are at greatest risk of HIV transmission.},\n\tlanguage = {eng},\n\tnumber = {2},\n\tjournal = {AIDS (London, England)},\n\tauthor = {Green, Nella and Hoenigl, Martin and Chaillon, Antoine and Anderson, Christy M. and Kosakovsky Pond, Sergei L. and Smith, Davey M. and Little, Susan J.},\n\tyear = {2017},\n\tpmid = {27831950},\n\tpmcid = {PMC5177524},\n\tkeywords = {Adolescent, Adult, California, Cohort Studies, Contact Tracing, HIV Infections, Humans, Young Adult},\n\tpages = {287--293},\n}\n\n\n\n","author_short":["Green, N.","Hoenigl, M.","Chaillon, A.","Anderson, C. M.","Kosakovsky Pond, S. L.","Smith, D. M.","Little, S. 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