The Impact of Maternal Depression During Pregnancy on Perinatal Outcomes: A Systematic Review and Meta-Analysis. Grigoriadis, S., VonderPorten, E. H., Mamisashvili, L., Tomlinson, G., Dennis, C., Koren, G., Steiner, M., Mousmanis, P., Cheung, A., & Radford, K. The Journal of Clinical Psychiatry, 74(4):0–0, April, 2013. Publisher: Physicians Postgraduate Press, Inc.![The Impact of Maternal Depression During Pregnancy on Perinatal Outcomes: A Systematic Review and Meta-Analysis [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Objective: Depression often remains undertreated during pregnancy and there is growing evidence that untoward perinatal outcomes can result. Our systematic review and meta-analysis was conducted to determine whether maternal depression during pregnancy is associated with adverse perinatal and infant outcomes. Data Sources: MEDLINE, EMBASE, CINAHL, and PsycINFO were searched from their start dates to June 2010. Keywords utilized included depressive/mood disorder, postpartum/postnatal, pregnancy/pregnancy trimesters, prenatal or antenatal, infant/neonatal outcomes, premature delivery, gestational age, birth weight, NICU, preeclampsia, breastfeeding, and Apgar. Study Selection: English language studies reporting on perinatal or child outcomes associated with maternal depression were included, 3,074 abstracts were reviewed, 735 articles retrieved, and 30 studies included. Data Extraction: Two independent reviewers extracted data and assessed article quality. All studies were included in the primary analyses, and between-group differences for subanalyses are also reported. Results: Thirty studies were eligible for inclusion. Premature delivery and decrease in breastfeeding initiation were significantly associated with maternal depression (odds ratio [OR] = 1.37; 95% CI, 1.04 to1.81; P = .024; and OR = 0.68; 95% CI, 0.61 to 0.76; P \textless .0001, respectively). While birth weight (mean difference = -19.53 g; 95% CI, -64.27 to 25.20; P = .392), low birth weight (OR = 1.21; 95% CI, 0.91 to 1.60; P = .195), neonatal intensive care unit admissions (OR = 1.43; 95% CI, 0.83 to 2.47; P = .195), and preeclampsia (OR = 1.35; 95% CI, 0.95 to 1.92; P = .089) did not show significant associations in the main analyses, some subanalyses were significant. Gestational age (mean difference = -0.19 weeks; 95% CI, -0.53 to 0.14; P = .262) and Apgar scores at 1 (mean difference = -0.05; 95% CI, -0.28 to 0.17; P = .638) and 5 minutes (mean difference = 0.01; 95% CI, -0.08 to 0.11; P = .782) did not demonstrate any significant associations with depression. For premature delivery, a convenience sample study design was associated with higher ORs (OR = 2.43; 95% CI, 1.47 to 4.01; P = .001). Conclusions: Maternal depression during pregnancy is associated with increased odds for premature delivery and decreased breastfeeding initiation; however, the effects are modest. More research of higher methodological quality is needed. © Copyright 2013 Physicians Postgraduate Press.
@article{grigoriadis_impact_2013,
title = {The {Impact} of {Maternal} {Depression} {During} {Pregnancy} on {Perinatal} {Outcomes}: {A} {Systematic} {Review} and {Meta}-{Analysis}},
volume = {74},
issn = {0160-6689},
url = {https://www.psychiatrist.com/jcp/depression/impact-maternal-depression-during-pregnancy-perinatal},
doi = {10.4088/JCP.12R07968},
abstract = {Objective: Depression often remains undertreated during pregnancy and there is growing evidence that untoward perinatal outcomes can result. Our systematic review and meta-analysis was conducted to determine whether maternal depression during pregnancy is associated with adverse perinatal and infant outcomes. Data Sources: MEDLINE, EMBASE, CINAHL, and PsycINFO were searched from their start dates to June 2010. Keywords utilized included depressive/mood disorder, postpartum/postnatal, pregnancy/pregnancy trimesters, prenatal or antenatal, infant/neonatal outcomes, premature delivery, gestational age, birth weight, NICU, preeclampsia, breastfeeding, and Apgar. Study Selection: English language studies reporting on perinatal or child outcomes associated with maternal depression were included, 3,074 abstracts were reviewed, 735 articles retrieved, and 30 studies included. Data Extraction: Two independent reviewers extracted data and assessed article quality. All studies were included in the primary analyses, and between-group differences for subanalyses are also reported. Results: Thirty studies were eligible for inclusion. Premature delivery and decrease in breastfeeding initiation were significantly associated with maternal depression (odds ratio [OR] = 1.37; 95\% CI, 1.04 to1.81; P = .024; and OR = 0.68; 95\% CI, 0.61 to 0.76; P {\textless} .0001, respectively). While birth weight (mean difference = -19.53 g; 95\% CI, -64.27 to 25.20; P = .392), low birth weight (OR = 1.21; 95\% CI, 0.91 to 1.60; P = .195), neonatal intensive care unit admissions (OR = 1.43; 95\% CI, 0.83 to 2.47; P = .195), and preeclampsia (OR = 1.35; 95\% CI, 0.95 to 1.92; P = .089) did not show significant associations in the main analyses, some subanalyses were significant. Gestational age (mean difference = -0.19 weeks; 95\% CI, -0.53 to 0.14; P = .262) and Apgar scores at 1 (mean difference = -0.05; 95\% CI, -0.28 to 0.17; P = .638) and 5 minutes (mean difference = 0.01; 95\% CI, -0.08 to 0.11; P = .782) did not demonstrate any significant associations with depression. For premature delivery, a convenience sample study design was associated with higher ORs (OR = 2.43; 95\% CI, 1.47 to 4.01; P = .001). Conclusions: Maternal depression during pregnancy is associated with increased odds for premature delivery and decreased breastfeeding initiation; however, the effects are modest. More research of higher methodological quality is needed. © Copyright 2013 Physicians Postgraduate Press.},
number = {4},
urldate = {2021-07-19},
journal = {The Journal of Clinical Psychiatry},
author = {Grigoriadis, Sophie and VonderPorten, Emily H. and Mamisashvili, Lana and Tomlinson, George and Dennis, Cindy-Lee and Koren, Gideon and Steiner, Meir and Mousmanis, Patricia and Cheung, Amy and Radford, Kim},
month = apr,
year = {2013},
note = {Publisher: Physicians Postgraduate Press, Inc.},
pages = {0--0},
}
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{"_id":"Coa55H2Bde7CHXfyM","bibbaseid":"grigoriadis-vonderporten-mamisashvili-tomlinson-dennis-koren-steiner-mousmanis-etal-theimpactofmaternaldepressionduringpregnancyonperinataloutcomesasystematicreviewandmetaanalysis-2013","author_short":["Grigoriadis, S.","VonderPorten, E. H.","Mamisashvili, L.","Tomlinson, G.","Dennis, C.","Koren, G.","Steiner, M.","Mousmanis, P.","Cheung, A.","Radford, K."],"bibdata":{"bibtype":"article","type":"article","title":"The Impact of Maternal Depression During Pregnancy on Perinatal Outcomes: A Systematic Review and Meta-Analysis","volume":"74","issn":"0160-6689","url":"https://www.psychiatrist.com/jcp/depression/impact-maternal-depression-during-pregnancy-perinatal","doi":"10.4088/JCP.12R07968","abstract":"Objective: Depression often remains undertreated during pregnancy and there is growing evidence that untoward perinatal outcomes can result. Our systematic review and meta-analysis was conducted to determine whether maternal depression during pregnancy is associated with adverse perinatal and infant outcomes. Data Sources: MEDLINE, EMBASE, CINAHL, and PsycINFO were searched from their start dates to June 2010. Keywords utilized included depressive/mood disorder, postpartum/postnatal, pregnancy/pregnancy trimesters, prenatal or antenatal, infant/neonatal outcomes, premature delivery, gestational age, birth weight, NICU, preeclampsia, breastfeeding, and Apgar. Study Selection: English language studies reporting on perinatal or child outcomes associated with maternal depression were included, 3,074 abstracts were reviewed, 735 articles retrieved, and 30 studies included. Data Extraction: Two independent reviewers extracted data and assessed article quality. All studies were included in the primary analyses, and between-group differences for subanalyses are also reported. Results: Thirty studies were eligible for inclusion. Premature delivery and decrease in breastfeeding initiation were significantly associated with maternal depression (odds ratio [OR] = 1.37; 95% CI, 1.04 to1.81; P = .024; and OR = 0.68; 95% CI, 0.61 to 0.76; P \\textless .0001, respectively). While birth weight (mean difference = -19.53 g; 95% CI, -64.27 to 25.20; P = .392), low birth weight (OR = 1.21; 95% CI, 0.91 to 1.60; P = .195), neonatal intensive care unit admissions (OR = 1.43; 95% CI, 0.83 to 2.47; P = .195), and preeclampsia (OR = 1.35; 95% CI, 0.95 to 1.92; P = .089) did not show significant associations in the main analyses, some subanalyses were significant. Gestational age (mean difference = -0.19 weeks; 95% CI, -0.53 to 0.14; P = .262) and Apgar scores at 1 (mean difference = -0.05; 95% CI, -0.28 to 0.17; P = .638) and 5 minutes (mean difference = 0.01; 95% CI, -0.08 to 0.11; P = .782) did not demonstrate any significant associations with depression. For premature delivery, a convenience sample study design was associated with higher ORs (OR = 2.43; 95% CI, 1.47 to 4.01; P = .001). Conclusions: Maternal depression during pregnancy is associated with increased odds for premature delivery and decreased breastfeeding initiation; however, the effects are modest. More research of higher methodological quality is needed. © Copyright 2013 Physicians Postgraduate Press.","number":"4","urldate":"2021-07-19","journal":"The Journal of Clinical Psychiatry","author":[{"propositions":[],"lastnames":["Grigoriadis"],"firstnames":["Sophie"],"suffixes":[]},{"propositions":[],"lastnames":["VonderPorten"],"firstnames":["Emily","H."],"suffixes":[]},{"propositions":[],"lastnames":["Mamisashvili"],"firstnames":["Lana"],"suffixes":[]},{"propositions":[],"lastnames":["Tomlinson"],"firstnames":["George"],"suffixes":[]},{"propositions":[],"lastnames":["Dennis"],"firstnames":["Cindy-Lee"],"suffixes":[]},{"propositions":[],"lastnames":["Koren"],"firstnames":["Gideon"],"suffixes":[]},{"propositions":[],"lastnames":["Steiner"],"firstnames":["Meir"],"suffixes":[]},{"propositions":[],"lastnames":["Mousmanis"],"firstnames":["Patricia"],"suffixes":[]},{"propositions":[],"lastnames":["Cheung"],"firstnames":["Amy"],"suffixes":[]},{"propositions":[],"lastnames":["Radford"],"firstnames":["Kim"],"suffixes":[]}],"month":"April","year":"2013","note":"Publisher: Physicians Postgraduate Press, Inc.","pages":"0–0","bibtex":"@article{grigoriadis_impact_2013,\n\ttitle = {The {Impact} of {Maternal} {Depression} {During} {Pregnancy} on {Perinatal} {Outcomes}: {A} {Systematic} {Review} and {Meta}-{Analysis}},\n\tvolume = {74},\n\tissn = {0160-6689},\n\turl = {https://www.psychiatrist.com/jcp/depression/impact-maternal-depression-during-pregnancy-perinatal},\n\tdoi = {10.4088/JCP.12R07968},\n\tabstract = {Objective: Depression often remains undertreated during pregnancy and there is growing evidence that untoward perinatal outcomes can result. Our systematic review and meta-analysis was conducted to determine whether maternal depression during pregnancy is associated with adverse perinatal and infant outcomes. Data Sources: MEDLINE, EMBASE, CINAHL, and PsycINFO were searched from their start dates to June 2010. Keywords utilized included depressive/mood disorder, postpartum/postnatal, pregnancy/pregnancy trimesters, prenatal or antenatal, infant/neonatal outcomes, premature delivery, gestational age, birth weight, NICU, preeclampsia, breastfeeding, and Apgar. Study Selection: English language studies reporting on perinatal or child outcomes associated with maternal depression were included, 3,074 abstracts were reviewed, 735 articles retrieved, and 30 studies included. Data Extraction: Two independent reviewers extracted data and assessed article quality. All studies were included in the primary analyses, and between-group differences for subanalyses are also reported. Results: Thirty studies were eligible for inclusion. Premature delivery and decrease in breastfeeding initiation were significantly associated with maternal depression (odds ratio [OR] = 1.37; 95\\% CI, 1.04 to1.81; P = .024; and OR = 0.68; 95\\% CI, 0.61 to 0.76; P {\\textless} .0001, respectively). While birth weight (mean difference = -19.53 g; 95\\% CI, -64.27 to 25.20; P = .392), low birth weight (OR = 1.21; 95\\% CI, 0.91 to 1.60; P = .195), neonatal intensive care unit admissions (OR = 1.43; 95\\% CI, 0.83 to 2.47; P = .195), and preeclampsia (OR = 1.35; 95\\% CI, 0.95 to 1.92; P = .089) did not show significant associations in the main analyses, some subanalyses were significant. Gestational age (mean difference = -0.19 weeks; 95\\% CI, -0.53 to 0.14; P = .262) and Apgar scores at 1 (mean difference = -0.05; 95\\% CI, -0.28 to 0.17; P = .638) and 5 minutes (mean difference = 0.01; 95\\% CI, -0.08 to 0.11; P = .782) did not demonstrate any significant associations with depression. For premature delivery, a convenience sample study design was associated with higher ORs (OR = 2.43; 95\\% CI, 1.47 to 4.01; P = .001). Conclusions: Maternal depression during pregnancy is associated with increased odds for premature delivery and decreased breastfeeding initiation; however, the effects are modest. More research of higher methodological quality is needed. © Copyright 2013 Physicians Postgraduate Press.},\n\tnumber = {4},\n\turldate = {2021-07-19},\n\tjournal = {The Journal of Clinical Psychiatry},\n\tauthor = {Grigoriadis, Sophie and VonderPorten, Emily H. and Mamisashvili, Lana and Tomlinson, George and Dennis, Cindy-Lee and Koren, Gideon and Steiner, Meir and Mousmanis, Patricia and Cheung, Amy and Radford, Kim},\n\tmonth = apr,\n\tyear = {2013},\n\tnote = {Publisher: Physicians Postgraduate Press, Inc.},\n\tpages = {0--0},\n}\n\n","author_short":["Grigoriadis, S.","VonderPorten, E. H.","Mamisashvili, L.","Tomlinson, G.","Dennis, C.","Koren, G.","Steiner, M.","Mousmanis, P.","Cheung, A.","Radford, K."],"key":"grigoriadis_impact_2013","id":"grigoriadis_impact_2013","bibbaseid":"grigoriadis-vonderporten-mamisashvili-tomlinson-dennis-koren-steiner-mousmanis-etal-theimpactofmaternaldepressionduringpregnancyonperinataloutcomesasystematicreviewandmetaanalysis-2013","role":"author","urls":{"Paper":"https://www.psychiatrist.com/jcp/depression/impact-maternal-depression-during-pregnancy-perinatal"},"metadata":{"authorlinks":{}},"html":""},"bibtype":"article","biburl":"https://bibbase.org/zotero/asrommel","dataSources":["J8fbWsdsy3xAaB3pX"],"keywords":[],"search_terms":["impact","maternal","depression","during","pregnancy","perinatal","outcomes","systematic","review","meta","analysis","grigoriadis","vonderporten","mamisashvili","tomlinson","dennis","koren","steiner","mousmanis","cheung","radford"],"title":"The Impact of Maternal Depression During Pregnancy on Perinatal Outcomes: A Systematic Review and Meta-Analysis","year":2013}