HEALTH TECHNOLOGY PERFORMANCE ASSESSMENT: REAL-WORLD EVIDENCE FOR PUBLIC HEALTHCARE SUSTAINABILITY. Guerra-Júnior, A. A., Pires de Lemos, L. L., Godman, B., Bennie, M., Osorio-de-Castro, C. G. S., Alvares, J., Heaney, A., Vassallo, C. A., Wettermark, B., Benguria-Arrate, G., Gutierrez-Ibarluzea, I., Santos, V. C. C., Petramale, C. A., & Acurcio, F. d. A. International Journal of Technology Assessment in Health Care, 33(2):279–287, 2017. ![HEALTH TECHNOLOGY PERFORMANCE ASSESSMENT: REAL-WORLD EVIDENCE FOR PUBLIC HEALTHCARE SUSTAINABILITY [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Objective: Health technology financing is often based on randomized controlled trials (RCTs), which are often the same ones used for licensing. Since they are designed to show the best possible results with typically Phase III studies conducted under ideal and highly controlled conditions to seek high internal validity and maximize the chance of demonstrating clinical benefit, they often do not reflect likely effectiveness in routine clinical care. Consequently, it is not surprising that technologies do not always perform in real life in the same way as controlled conditions. Since financing (and price paid) decisions can be made with overestimated results, health authorities need to ask whether health systems achieve the results they expect when they choose to pay for a technology. The optimal way to answer this question is to assess the performance of financed technologies in real world settings. Health technology performance assessment (HTpA) refers to the systematic evaluation of the properties, effects, and/or impact of a health intervention or health technology in the real world to provide information for investment/ disinvestment decisions and clinical guideline updates. The objective is to describe the development and principal aspects of the Guideline for HTpA commissioned by the Brazilian Ministry of Health. Method: Extensive literature review, refinement with experts across countries and public consultation. Results: A comprehensive guideline was developed, which has been adopted by the Brazilian government. Conclusion: We believe the guideline, with its particular focus on disinvestment, along with the creation of a specific program for HTpA, will allow the institutionalization and continuous improvement of the scientific methods to use real world evidence to optimize available resources not only in Brazil but across countries.
@article{guerra-junior_health_2017-1,
title = {{HEALTH} {TECHNOLOGY} {PERFORMANCE} {ASSESSMENT}: {REAL}-{WORLD} {EVIDENCE} {FOR} {PUBLIC} {HEALTHCARE} {SUSTAINABILITY}},
volume = {33},
issn = {0266-4623, 1471-6348},
shorttitle = {{HEALTH} {TECHNOLOGY} {PERFORMANCE} {ASSESSMENT}},
url = {https://www.cambridge.org/core/product/identifier/S0266462317000423/type/journal_article},
doi = {10.1017/S0266462317000423},
abstract = {Objective: Health technology financing is often based on randomized controlled trials (RCTs), which are often the same ones used for licensing. Since they are designed to show the best possible results with typically Phase III studies conducted under ideal and highly controlled conditions to seek high internal validity and maximize the chance of demonstrating clinical benefit, they often do not reflect likely effectiveness in routine clinical care. Consequently, it is not surprising that technologies do not always perform in real life in the same way as controlled conditions. Since financing (and price paid) decisions can be made with overestimated results, health authorities need to ask whether health systems achieve the results they expect when they choose to pay for a technology. The optimal way to answer this question is to assess the performance of financed technologies in real world settings. Health technology performance assessment (HTpA) refers to the systematic evaluation of the properties, effects, and/or impact of a health intervention or health technology in the real world to provide information for investment/ disinvestment decisions and clinical guideline updates. The objective is to describe the development and principal aspects of the Guideline for HTpA commissioned by the Brazilian Ministry of Health. Method: Extensive literature review, refinement with experts across countries and public consultation. Results: A comprehensive guideline was developed, which has been adopted by the Brazilian government. Conclusion: We believe the guideline, with its particular focus on disinvestment, along with the creation of a specific program for HTpA, will allow the institutionalization and continuous improvement of the scientific methods to use real world evidence to optimize available resources not only in Brazil but across countries.},
language = {en},
number = {2},
urldate = {2019-05-02},
journal = {International Journal of Technology Assessment in Health Care},
author = {Guerra-Júnior, Augusto Afonso and Pires de Lemos, Lívia Lovato and Godman, Brian and Bennie, Marion and Osorio-de-Castro, Cláudia Garcia Serpa and Alvares, Juliana and Heaney, Aine and Vassallo, Carlos Alberto and Wettermark, Björn and Benguria-Arrate, Gaizka and Gutierrez-Ibarluzea, Iñaki and Santos, Vania Cristina Canuto and Petramale, Clarice Alegre and Acurcio, Fransciso de Assis},
year = {2017},
pages = {279--287},
file = {Guerra-Júnior et al. - 2017 - HEALTH TECHNOLOGY PERFORMANCE ASSESSMENT REAL-WOR.pdf:/Users/neil.hawkins/Zotero/storage/ZC38MRYT/Guerra-Júnior et al. - 2017 - HEALTH TECHNOLOGY PERFORMANCE ASSESSMENT REAL-WOR.pdf:application/pdf},
}
Downloads: 0
{"_id":"vMjhsXfwXfdomN23j","bibbaseid":"guerrajnior-piresdelemos-godman-bennie-osoriodecastro-alvares-heaney-vassallo-etal-healthtechnologyperformanceassessmentrealworldevidenceforpublichealthcaresustainability-2017","author_short":["Guerra-Júnior, A. A.","Pires de Lemos, L. L.","Godman, B.","Bennie, M.","Osorio-de-Castro, C. G. S.","Alvares, J.","Heaney, A.","Vassallo, C. A.","Wettermark, B.","Benguria-Arrate, G.","Gutierrez-Ibarluzea, I.","Santos, V. C. C.","Petramale, C. A.","Acurcio, F. d. A."],"bibdata":{"bibtype":"article","type":"article","title":"HEALTH TECHNOLOGY PERFORMANCE ASSESSMENT: REAL-WORLD EVIDENCE FOR PUBLIC HEALTHCARE SUSTAINABILITY","volume":"33","issn":"0266-4623, 1471-6348","shorttitle":"HEALTH TECHNOLOGY PERFORMANCE ASSESSMENT","url":"https://www.cambridge.org/core/product/identifier/S0266462317000423/type/journal_article","doi":"10.1017/S0266462317000423","abstract":"Objective: Health technology financing is often based on randomized controlled trials (RCTs), which are often the same ones used for licensing. Since they are designed to show the best possible results with typically Phase III studies conducted under ideal and highly controlled conditions to seek high internal validity and maximize the chance of demonstrating clinical benefit, they often do not reflect likely effectiveness in routine clinical care. Consequently, it is not surprising that technologies do not always perform in real life in the same way as controlled conditions. Since financing (and price paid) decisions can be made with overestimated results, health authorities need to ask whether health systems achieve the results they expect when they choose to pay for a technology. The optimal way to answer this question is to assess the performance of financed technologies in real world settings. Health technology performance assessment (HTpA) refers to the systematic evaluation of the properties, effects, and/or impact of a health intervention or health technology in the real world to provide information for investment/ disinvestment decisions and clinical guideline updates. The objective is to describe the development and principal aspects of the Guideline for HTpA commissioned by the Brazilian Ministry of Health. Method: Extensive literature review, refinement with experts across countries and public consultation. Results: A comprehensive guideline was developed, which has been adopted by the Brazilian government. Conclusion: We believe the guideline, with its particular focus on disinvestment, along with the creation of a specific program for HTpA, will allow the institutionalization and continuous improvement of the scientific methods to use real world evidence to optimize available resources not only in Brazil but across countries.","language":"en","number":"2","urldate":"2019-05-02","journal":"International Journal of Technology Assessment in Health Care","author":[{"propositions":[],"lastnames":["Guerra-Júnior"],"firstnames":["Augusto","Afonso"],"suffixes":[]},{"propositions":["Pires","de"],"lastnames":["Lemos"],"firstnames":["Lívia","Lovato"],"suffixes":[]},{"propositions":[],"lastnames":["Godman"],"firstnames":["Brian"],"suffixes":[]},{"propositions":[],"lastnames":["Bennie"],"firstnames":["Marion"],"suffixes":[]},{"propositions":[],"lastnames":["Osorio-de-Castro"],"firstnames":["Cláudia","Garcia","Serpa"],"suffixes":[]},{"propositions":[],"lastnames":["Alvares"],"firstnames":["Juliana"],"suffixes":[]},{"propositions":[],"lastnames":["Heaney"],"firstnames":["Aine"],"suffixes":[]},{"propositions":[],"lastnames":["Vassallo"],"firstnames":["Carlos","Alberto"],"suffixes":[]},{"propositions":[],"lastnames":["Wettermark"],"firstnames":["Björn"],"suffixes":[]},{"propositions":[],"lastnames":["Benguria-Arrate"],"firstnames":["Gaizka"],"suffixes":[]},{"propositions":[],"lastnames":["Gutierrez-Ibarluzea"],"firstnames":["Iñaki"],"suffixes":[]},{"propositions":[],"lastnames":["Santos"],"firstnames":["Vania","Cristina","Canuto"],"suffixes":[]},{"propositions":[],"lastnames":["Petramale"],"firstnames":["Clarice","Alegre"],"suffixes":[]},{"propositions":[],"lastnames":["Acurcio"],"firstnames":["Fransciso","de","Assis"],"suffixes":[]}],"year":"2017","pages":"279–287","file":"Guerra-Júnior et al. - 2017 - HEALTH TECHNOLOGY PERFORMANCE ASSESSMENT REAL-WOR.pdf:/Users/neil.hawkins/Zotero/storage/ZC38MRYT/Guerra-Júnior et al. - 2017 - HEALTH TECHNOLOGY PERFORMANCE ASSESSMENT REAL-WOR.pdf:application/pdf","bibtex":"@article{guerra-junior_health_2017-1,\n\ttitle = {{HEALTH} {TECHNOLOGY} {PERFORMANCE} {ASSESSMENT}: {REAL}-{WORLD} {EVIDENCE} {FOR} {PUBLIC} {HEALTHCARE} {SUSTAINABILITY}},\n\tvolume = {33},\n\tissn = {0266-4623, 1471-6348},\n\tshorttitle = {{HEALTH} {TECHNOLOGY} {PERFORMANCE} {ASSESSMENT}},\n\turl = {https://www.cambridge.org/core/product/identifier/S0266462317000423/type/journal_article},\n\tdoi = {10.1017/S0266462317000423},\n\tabstract = {Objective: Health technology financing is often based on randomized controlled trials (RCTs), which are often the same ones used for licensing. Since they are designed to show the best possible results with typically Phase III studies conducted under ideal and highly controlled conditions to seek high internal validity and maximize the chance of demonstrating clinical benefit, they often do not reflect likely effectiveness in routine clinical care. Consequently, it is not surprising that technologies do not always perform in real life in the same way as controlled conditions. Since financing (and price paid) decisions can be made with overestimated results, health authorities need to ask whether health systems achieve the results they expect when they choose to pay for a technology. The optimal way to answer this question is to assess the performance of financed technologies in real world settings. Health technology performance assessment (HTpA) refers to the systematic evaluation of the properties, effects, and/or impact of a health intervention or health technology in the real world to provide information for investment/ disinvestment decisions and clinical guideline updates. The objective is to describe the development and principal aspects of the Guideline for HTpA commissioned by the Brazilian Ministry of Health. Method: Extensive literature review, refinement with experts across countries and public consultation. Results: A comprehensive guideline was developed, which has been adopted by the Brazilian government. Conclusion: We believe the guideline, with its particular focus on disinvestment, along with the creation of a specific program for HTpA, will allow the institutionalization and continuous improvement of the scientific methods to use real world evidence to optimize available resources not only in Brazil but across countries.},\n\tlanguage = {en},\n\tnumber = {2},\n\turldate = {2019-05-02},\n\tjournal = {International Journal of Technology Assessment in Health Care},\n\tauthor = {Guerra-Júnior, Augusto Afonso and Pires de Lemos, Lívia Lovato and Godman, Brian and Bennie, Marion and Osorio-de-Castro, Cláudia Garcia Serpa and Alvares, Juliana and Heaney, Aine and Vassallo, Carlos Alberto and Wettermark, Björn and Benguria-Arrate, Gaizka and Gutierrez-Ibarluzea, Iñaki and Santos, Vania Cristina Canuto and Petramale, Clarice Alegre and Acurcio, Fransciso de Assis},\n\tyear = {2017},\n\tpages = {279--287},\n\tfile = {Guerra-Júnior et al. - 2017 - HEALTH TECHNOLOGY PERFORMANCE ASSESSMENT REAL-WOR.pdf:/Users/neil.hawkins/Zotero/storage/ZC38MRYT/Guerra-Júnior et al. - 2017 - HEALTH TECHNOLOGY PERFORMANCE ASSESSMENT REAL-WOR.pdf:application/pdf},\n}\n\n","author_short":["Guerra-Júnior, A. A.","Pires de Lemos, L. L.","Godman, B.","Bennie, M.","Osorio-de-Castro, C. G. S.","Alvares, J.","Heaney, A.","Vassallo, C. A.","Wettermark, B.","Benguria-Arrate, G.","Gutierrez-Ibarluzea, I.","Santos, V. C. C.","Petramale, C. A.","Acurcio, F. d. A."],"bibbaseid":"guerrajnior-piresdelemos-godman-bennie-osoriodecastro-alvares-heaney-vassallo-etal-healthtechnologyperformanceassessmentrealworldevidenceforpublichealthcaresustainability-2017","role":"author","urls":{"Paper":"https://www.cambridge.org/core/product/identifier/S0266462317000423/type/journal_article"},"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/f/FfNE7kWA6pCvwcJZF/myPubs.bib","dataSources":["ZaHtWavQhcwZqKLNF","iRRNaRs6FkffgErta","v8uQmZsBpiqycmskv"],"keywords":[],"search_terms":["health","technology","performance","assessment","real","world","evidence","public","healthcare","sustainability","guerra-júnior","pires de lemos","godman","bennie","osorio-de-castro","alvares","heaney","vassallo","wettermark","benguria-arrate","gutierrez-ibarluzea","santos","petramale","acurcio"],"title":"HEALTH TECHNOLOGY PERFORMANCE ASSESSMENT: REAL-WORLD EVIDENCE FOR PUBLIC HEALTHCARE SUSTAINABILITY","year":2017}