@article{gulec_intrathecal_2014-2,
	title = {Intrathecal bupivacaine or levobupivacaine: {Which} should be used for elderly patients?},
	volume = {42},
	issn = {1473-2300},
	url = {http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L372861260},
	doi = {10.1177/0300060513496737},
	abstract = {Objectives: To compare two intrathecal anaesthetics, bupivacaine and levobupivacaine, for their effects on motor and sensory blockade and haemodynamics in patients aged -65 years undergoing transurethral resection of the prostate (TUR-P) or transurethral resection of the urinary bladder (TUR-M). Methods: Patients scheduled to undergo TUR-P or TUR-M were randomized to receive either 3ml (15 mg) 0.5\% isobaric levobupivacaine (group L) or 3ml (15 mg) of 0.5\% hyperbaric bupivacaine (group B) for spinal anaesthesia. The onset time, maximum level and time to reach the maximum level of sensory and motor blockade were recorded. Changes to haemodynamic parameters were also recorded. Results: The study randomized 100 patients: 57 to group L and 43 to group B. Levobupivacaine did not cause any significant changes in haemodynamic parameters, including systolic blood pressure, and showed a similar sensory block onset time compared with bupivacaine, but it had a significantly longer motor block onset time compared with bupivacaine. Conclusion: These current findings suggest that levobupivacaine can be used as a substitute for bupivacaine for spinal anaesthesia in elderly patients ≥65 years of age undergoing elective TUR-P or TUR-M operations. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.},
	number = {2},
	journal = {Journal of International Medical Research},
	author = {Gulec, D. and Karsli, B. and Ertugrul, F. and Bigat, Z. and Kayacan, N.},
	year = {2014},
	keywords = {Spinocan, aged, article, bupivacaine, chirocaine, clinical trial, hemodynamics, human, intrathecal drug administration, levobupivacaine, major clinical study, male, marcaine, randomization, randomized controlled trial, spinal anesthesia, spinal needle, systolic blood pressure, transurethral resection},
	pages = {376--385}
}

{"_id":"bP859PFtxwAEEF4MQ","bibbaseid":"gulec-karsli-ertugrul-bigat-kayacan-intrathecalbupivacaineorlevobupivacainewhichshouldbeusedforelderlypatients-2014","downloads":0,"creationDate":"2019-02-11T13:21:01.381Z","title":"Intrathecal bupivacaine or levobupivacaine: Which should be used for elderly patients?","author_short":["Gulec, D.","Karsli, B.","Ertugrul, F.","Bigat, Z.","Kayacan, N."],"year":2014,"bibtype":"article","biburl":"https://bibbase.org/zotero/jkuemmel","bibdata":{"bibtype":"article","type":"article","title":"Intrathecal bupivacaine or levobupivacaine: Which should be used for elderly patients?","volume":"42","issn":"1473-2300","url":"http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L372861260","doi":"10.1177/0300060513496737","abstract":"Objectives: To compare two intrathecal anaesthetics, bupivacaine and levobupivacaine, for their effects on motor and sensory blockade and haemodynamics in patients aged -65 years undergoing transurethral resection of the prostate (TUR-P) or transurethral resection of the urinary bladder (TUR-M). Methods: Patients scheduled to undergo TUR-P or TUR-M were randomized to receive either 3ml (15 mg) 0.5% isobaric levobupivacaine (group L) or 3ml (15 mg) of 0.5% hyperbaric bupivacaine (group B) for spinal anaesthesia. The onset time, maximum level and time to reach the maximum level of sensory and motor blockade were recorded. Changes to haemodynamic parameters were also recorded. Results: The study randomized 100 patients: 57 to group L and 43 to group B. Levobupivacaine did not cause any significant changes in haemodynamic parameters, including systolic blood pressure, and showed a similar sensory block onset time compared with bupivacaine, but it had a significantly longer motor block onset time compared with bupivacaine. Conclusion: These current findings suggest that levobupivacaine can be used as a substitute for bupivacaine for spinal anaesthesia in elderly patients ≥65 years of age undergoing elective TUR-P or TUR-M operations. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.","number":"2","journal":"Journal of International Medical Research","author":[{"propositions":[],"lastnames":["Gulec"],"firstnames":["D."],"suffixes":[]},{"propositions":[],"lastnames":["Karsli"],"firstnames":["B."],"suffixes":[]},{"propositions":[],"lastnames":["Ertugrul"],"firstnames":["F."],"suffixes":[]},{"propositions":[],"lastnames":["Bigat"],"firstnames":["Z."],"suffixes":[]},{"propositions":[],"lastnames":["Kayacan"],"firstnames":["N."],"suffixes":[]}],"year":"2014","keywords":"Spinocan, aged, article, bupivacaine, chirocaine, clinical trial, hemodynamics, human, intrathecal drug administration, levobupivacaine, major clinical study, male, marcaine, randomization, randomized controlled trial, spinal anesthesia, spinal needle, systolic blood pressure, transurethral resection","pages":"376–385","bibtex":"@article{gulec_intrathecal_2014-2,\n\ttitle = {Intrathecal bupivacaine or levobupivacaine: {Which} should be used for elderly patients?},\n\tvolume = {42},\n\tissn = {1473-2300},\n\turl = {http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L372861260},\n\tdoi = {10.1177/0300060513496737},\n\tabstract = {Objectives: To compare two intrathecal anaesthetics, bupivacaine and levobupivacaine, for their effects on motor and sensory blockade and haemodynamics in patients aged -65 years undergoing transurethral resection of the prostate (TUR-P) or transurethral resection of the urinary bladder (TUR-M). Methods: Patients scheduled to undergo TUR-P or TUR-M were randomized to receive either 3ml (15 mg) 0.5\\% isobaric levobupivacaine (group L) or 3ml (15 mg) of 0.5\\% hyperbaric bupivacaine (group B) for spinal anaesthesia. The onset time, maximum level and time to reach the maximum level of sensory and motor blockade were recorded. Changes to haemodynamic parameters were also recorded. Results: The study randomized 100 patients: 57 to group L and 43 to group B. Levobupivacaine did not cause any significant changes in haemodynamic parameters, including systolic blood pressure, and showed a similar sensory block onset time compared with bupivacaine, but it had a significantly longer motor block onset time compared with bupivacaine. Conclusion: These current findings suggest that levobupivacaine can be used as a substitute for bupivacaine for spinal anaesthesia in elderly patients ≥65 years of age undergoing elective TUR-P or TUR-M operations. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.},\n\tnumber = {2},\n\tjournal = {Journal of International Medical Research},\n\tauthor = {Gulec, D. and Karsli, B. and Ertugrul, F. and Bigat, Z. and Kayacan, N.},\n\tyear = {2014},\n\tkeywords = {Spinocan, aged, article, bupivacaine, chirocaine, clinical trial, hemodynamics, human, intrathecal drug administration, levobupivacaine, major clinical study, male, marcaine, randomization, randomized controlled trial, spinal anesthesia, spinal needle, systolic blood pressure, transurethral resection},\n\tpages = {376--385}\n}\n\n","author_short":["Gulec, D.","Karsli, B.","Ertugrul, F.","Bigat, Z.","Kayacan, N."],"key":"gulec_intrathecal_2014-2","id":"gulec_intrathecal_2014-2","bibbaseid":"gulec-karsli-ertugrul-bigat-kayacan-intrathecalbupivacaineorlevobupivacainewhichshouldbeusedforelderlypatients-2014","role":"author","urls":{"Paper":"http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L372861260"},"keyword":["Spinocan","aged","article","bupivacaine","chirocaine","clinical trial","hemodynamics","human","intrathecal drug administration","levobupivacaine","major clinical study","male","marcaine","randomization","randomized controlled trial","spinal anesthesia","spinal needle","systolic blood pressure","transurethral resection"],"downloads":0},"search_terms":["intrathecal","bupivacaine","levobupivacaine","used","elderly","patients","gulec","karsli","ertugrul","bigat","kayacan"],"keywords":["spinocan","aged","article","bupivacaine","chirocaine","clinical trial","hemodynamics","human","intrathecal drug administration","levobupivacaine","major clinical study","male","marcaine","randomization","randomized controlled trial","spinal anesthesia","spinal needle","systolic blood pressure","transurethral resection"],"authorIDs":[],"dataSources":["nGDaM3ijM4PbPdhb7"]}