@article{gurnani_controlled_2020,
	title = {Controlled radical polymerization in dispersed systems for biological applications},
	volume = {102},
	issn = {0079-6700},
	doi = {10.1016/j.progpolymsci.2020.101209},
	abstract = {Polymeric nanoparticles show great promise in a range of biomedical applications, improving pharmacokinetic properties, dose requirements and immune response in drug delivery and bioimaging. Common synthesis techniques such as self-assembly, while prevalent, are unscalable and require the use of organic solvents, or extensive purification. In contrast, recent developments in dispersed state reversible deactivation radical polymerization allow the preparation of well-defined nanomaterials in fully aqueous environments often achieving full monomer conversion, and thus direct use in biological environments without purification in high quantities. These techniques have allowed the preparation of a variety of nanoparticle architectures (nanogel, latex, micelle, nanoworms, vesicles), using ATRP, RAFT and NMP, which in many cases perform significantly better than free radical alternatives. This review focuses on the biological relevance of RDRP in dispersed systems, covering miniemulsion, dispersion, suspension and emulsion polymerizations. (C) 2020 Elsevier B.V. All rights reserved.},
	urldate = {2020-04-28},
	journal = {PROGRESS IN POLYMER SCIENCE},
	author = {Gurnani, Pratik and Perrier, Sebastien},
	month = mar,
	year = {2020},
}

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