Selective optical drive of thalamic reticular nucleus generates thalamic bursts and cortical spindles. Halassa, M. M, Siegle, J. H, Ritt, J. T, Ting, J. T, Feng, G., & Moore, C. I Nature Neuroscience, 14(9):1118–1120, September, 2011.
Selective optical drive of thalamic reticular nucleus generates thalamic bursts and cortical spindles [link]Paper  doi  abstract   bibtex   4 downloads  
The thalamic reticular nucleus (TRN) is hypothesized to regulate neocortical rhythms and behavioral states. Using optogenetics and multi-electrode recording in behaving mice, we found that brief selective drive of TRN switched the thalamocortical firing mode from tonic to bursting and generated state-dependent neocortical spindles. These findings provide causal support for the involvement of the TRN in state regulation in vivo and introduce a new model for addressing the role of this structure in behavior.
@article{halassa_selective_2011,
	title = {Selective optical drive of thalamic reticular nucleus generates thalamic bursts and cortical spindles},
	volume = {14},
	issn = {1097-6256, 1546-1726},
	url = {http://www.nature.com/articles/nn.2880},
	doi = {10.1038/nn.2880},
	abstract = {The thalamic reticular nucleus (TRN) is hypothesized to regulate neocortical rhythms and behavioral states. Using optogenetics and multi-electrode recording in behaving mice, we found that brief selective drive of TRN switched the thalamocortical firing mode from tonic to bursting and generated state-dependent neocortical spindles. These findings provide causal support for the involvement of the TRN in state regulation in vivo and introduce a new model for addressing the role of this structure in behavior.},
	language = {en},
	number = {9},
	urldate = {2020-03-12},
	journal = {Nature Neuroscience},
	author = {Halassa, Michael M and Siegle, Joshua H and Ritt, Jason T and Ting, Jonathan T and Feng, Guoping and Moore, Christopher I},
	month = sep,
	year = {2011},
	pages = {1118--1120},
	file = {Accepted Version:/Users/jjallen/Zotero/storage/XVWQJ3W4/Halassa et al. - 2011 - Selective optical drive of thalamic reticular nucl.pdf:application/pdf}
}

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