Time-course of the auditory BOLD response to scanner noise. Hall, D. A., Summerfield, A. Q., Gonçalves, M. S., Foster, J. R., Palmer, A. R., & Bowtell, R. W. Magnetic Resonance in Medicine, 43(4):601–606, 2000. ISBN: 0740-3194 (Print)\n0740-3194 (Linking)
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It is a concern for auditory fMRI studies that acoustic noise generated by the scanner produces an auditory response that can confound stimulus-induced activation. To establish how to minimize this problem, the present study mapped the time-course of the auditory response to a burst of acoustic scanner noise by employing a single-event method. Recorded bursts of scanner noise were interspersed with clustered-volume acquisitions at a range of stimulus-to-imaging delays to map the response with a temporal resolution of 1 sec. There were strong responses (1.5% signal change) to scanner noise in primary and secondary auditory cortex. In both cortical areas, the mean response rose to a peak by 4-5 sec after stimulus onset and decayed after a further 5-8 sec. The time course indicates that noise contamination in auditory fMRI can be substantially reduced by using a 9-12-sec repetition time, thus maximizing the dynamic range available for displaying the response to acoustical stimuli of interest.
@article{hall_time-course_2000,
	title = {Time-course of the auditory {BOLD} response to scanner noise},
	volume = {43},
	issn = {07403194},
	doi = {10.1002/(SICI)1522-2594(200004)43:4<601::AID-MRM16>3.0.CO;2-R},
	abstract = {It is a concern for auditory fMRI studies that acoustic noise generated by the scanner produces an auditory response that can confound stimulus-induced activation. To establish how to minimize this problem, the present study mapped the time-course of the auditory response to a burst of acoustic scanner noise by employing a single-event method. Recorded bursts of scanner noise were interspersed with clustered-volume acquisitions at a range of stimulus-to-imaging delays to map the response with a temporal resolution of 1 sec. There were strong responses (1.5\% signal change) to scanner noise in primary and secondary auditory cortex. In both cortical areas, the mean response rose to a peak by 4-5 sec after stimulus onset and decayed after a further 5-8 sec. The time course indicates that noise contamination in auditory fMRI can be substantially reduced by using a 9-12-sec repetition time, thus maximizing the dynamic range available for displaying the response to acoustical stimuli of interest.},
	number = {4},
	journal = {Magnetic Resonance in Medicine},
	author = {Hall, Deborah A. and Summerfield, A. Quentin and Gonçalves, Miguel S. and Foster, John R. and Palmer, Alan R. and Bowtell, Richard W.},
	year = {2000},
	pmid = {10748437},
	note = {ISBN: 0740-3194 (Print){\textbackslash}n0740-3194 (Linking)},
	keywords = {Auditory, BOLD response, Scanner noise},
	pages = {601--606},
}

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