@article{
 title = {Differences in Glycemic Variability Between Normoglycemic and Prediabetic Subjects},
 type = {article},
 year = {2014},
 identifiers = {[object Object]},
 keywords = {cgms,continuous glucose monitoring,glucose homeostasis,glucose measurement systems,glycemic variability,hba1c,it became possible to,normal glucose tolerance,prediabetes,reliable and comfortable continuous,with the introduction of},
 id = {6637486e-9ca4-305d-a5cc-6885fcb99130},
 created = {2015-10-06T16:39:30.000Z},
 file_attached = {true},
 profile_id = {9119439d-54eb-3aeb-9ae6-8bf806ce7a35},
 group_id = {d83c42cd-843c-302b-9a7f-a839f548dcf7},
 last_modified = {2015-10-06T16:39:30.000Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 abstract = {So far the criteria for NGT and abnormal glucose tolerance (AGT) are based on HbA1c and 75 g oGTT. We present data on GV and diurnal profiles in stratified cohorts with AGT versus controls. 28 NGT, 42 AGT (15 IGT, 11 IFG, 16 CGI) matched for age and BMI classified by 75 g oGTT underwent a CGM with test meal (TM). Diurnal profiles, glucose excursion after TM, and GV (SD, MAGE) were calculated for day 2 and 3. HbA1c, with its values of 5.5 +/- 0.37% versus 5.65 +/- 0.36%, was within normal range. Average interstitial glucose (AiG) was 5.84 +/- 0.52 mmol/l) in NGT and 6.35 +/- 0.65 mmol/l in AGT (P = .002). The 2 h incremental area under curve (iAUC) from TM until 2 h after TM was 1.94 +/- 1.31 mmol/l*h versus 2.89 ( +/- 1.75) mmol/l*h (P = .012), AiG 2 hours after TM was 5.99 +/- 1.14 mmol/l*d versus 6.64 +/- 1.30 mmol/l (P = .035). Peaks of AiG after TM were 7.69 +/- 1.48 mmol/l*d versus 9.18 +/- 1.67 mmol/l*d (P = .001). SD was significantly higher for AGT (1.12 +/- 0.37 vs. 0.85 +/- 0.32 mmol/l, P = .01) and MAGE 2.26 +/- 0.84 vs. 1.60 +/- 0.69 mmol/l, P = .005). In this comparative analysis NGT and AGT well matched for age, BMI, and comorbidities, CGM revealed significant differences in daytime AiG, pp glucose excursion and postprandial peaks. SD and MAGE was significantly higher for subjects with AGT. I Impaired glucose homeostasis a better characterizes degree of AGTe than HbA1c and 75 g OGTT.},
 bibtype = {article},
 author = {Hanefeld, M and Sulk, S and Helbig, M and Thomas, A and Kohler, C},
 journal = {J Diabetes Sci Technol}
}

{"_id":"be2FWNyJjwRGzGc7H","bibbaseid":"hanefeld-sulk-helbig-thomas-kohler-differencesinglycemicvariabilitybetweennormoglycemicandprediabeticsubjects-2014","downloads":0,"creationDate":"2015-10-06T16:40:33.510Z","title":"Differences in Glycemic Variability Between Normoglycemic and Prediabetic Subjects","author_short":["Hanefeld, M.","Sulk, S.","Helbig, M.","Thomas, A.","Kohler, C."],"year":2014,"bibtype":"article","biburl":null,"bibdata":{"title":"Differences in Glycemic Variability Between Normoglycemic and Prediabetic Subjects","type":"article","year":"2014","identifiers":"[object Object]","keywords":"cgms,continuous glucose monitoring,glucose homeostasis,glucose measurement systems,glycemic variability,hba1c,it became possible to,normal glucose tolerance,prediabetes,reliable and comfortable continuous,with the introduction of","id":"6637486e-9ca4-305d-a5cc-6885fcb99130","created":"2015-10-06T16:39:30.000Z","file_attached":"true","profile_id":"9119439d-54eb-3aeb-9ae6-8bf806ce7a35","group_id":"d83c42cd-843c-302b-9a7f-a839f548dcf7","last_modified":"2015-10-06T16:39:30.000Z","read":false,"starred":false,"authored":false,"confirmed":false,"hidden":false,"abstract":"So far the criteria for NGT and abnormal glucose tolerance (AGT) are based on HbA1c and 75 g oGTT. We present data on GV and diurnal profiles in stratified cohorts with AGT versus controls. 28 NGT, 42 AGT (15 IGT, 11 IFG, 16 CGI) matched for age and BMI classified by 75 g oGTT underwent a CGM with test meal (TM). Diurnal profiles, glucose excursion after TM, and GV (SD, MAGE) were calculated for day 2 and 3. HbA1c, with its values of 5.5 +/- 0.37% versus 5.65 +/- 0.36%, was within normal range. Average interstitial glucose (AiG) was 5.84 +/- 0.52 mmol/l) in NGT and 6.35 +/- 0.65 mmol/l in AGT (P = .002). The 2 h incremental area under curve (iAUC) from TM until 2 h after TM was 1.94 +/- 1.31 mmol/l*h versus 2.89 ( +/- 1.75) mmol/l*h (P = .012), AiG 2 hours after TM was 5.99 +/- 1.14 mmol/l*d versus 6.64 +/- 1.30 mmol/l (P = .035). Peaks of AiG after TM were 7.69 +/- 1.48 mmol/l*d versus 9.18 +/- 1.67 mmol/l*d (P = .001). SD was significantly higher for AGT (1.12 +/- 0.37 vs. 0.85 +/- 0.32 mmol/l, P = .01) and MAGE 2.26 +/- 0.84 vs. 1.60 +/- 0.69 mmol/l, P = .005). In this comparative analysis NGT and AGT well matched for age, BMI, and comorbidities, CGM revealed significant differences in daytime AiG, pp glucose excursion and postprandial peaks. SD and MAGE was significantly higher for subjects with AGT. I Impaired glucose homeostasis a better characterizes degree of AGTe than HbA1c and 75 g OGTT.","bibtype":"article","author":"Hanefeld, M and Sulk, S and Helbig, M and Thomas, A and Kohler, C","journal":"J Diabetes Sci Technol","bibtex":"@article{\n title = {Differences in Glycemic Variability Between Normoglycemic and Prediabetic Subjects},\n type = {article},\n year = {2014},\n identifiers = {[object Object]},\n keywords = {cgms,continuous glucose monitoring,glucose homeostasis,glucose measurement systems,glycemic variability,hba1c,it became possible to,normal glucose tolerance,prediabetes,reliable and comfortable continuous,with the introduction of},\n id = {6637486e-9ca4-305d-a5cc-6885fcb99130},\n created = {2015-10-06T16:39:30.000Z},\n file_attached = {true},\n profile_id = {9119439d-54eb-3aeb-9ae6-8bf806ce7a35},\n group_id = {d83c42cd-843c-302b-9a7f-a839f548dcf7},\n last_modified = {2015-10-06T16:39:30.000Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {false},\n hidden = {false},\n abstract = {So far the criteria for NGT and abnormal glucose tolerance (AGT) are based on HbA1c and 75 g oGTT. We present data on GV and diurnal profiles in stratified cohorts with AGT versus controls. 28 NGT, 42 AGT (15 IGT, 11 IFG, 16 CGI) matched for age and BMI classified by 75 g oGTT underwent a CGM with test meal (TM). Diurnal profiles, glucose excursion after TM, and GV (SD, MAGE) were calculated for day 2 and 3. HbA1c, with its values of 5.5 +/- 0.37% versus 5.65 +/- 0.36%, was within normal range. Average interstitial glucose (AiG) was 5.84 +/- 0.52 mmol/l) in NGT and 6.35 +/- 0.65 mmol/l in AGT (P = .002). The 2 h incremental area under curve (iAUC) from TM until 2 h after TM was 1.94 +/- 1.31 mmol/l*h versus 2.89 ( +/- 1.75) mmol/l*h (P = .012), AiG 2 hours after TM was 5.99 +/- 1.14 mmol/l*d versus 6.64 +/- 1.30 mmol/l (P = .035). Peaks of AiG after TM were 7.69 +/- 1.48 mmol/l*d versus 9.18 +/- 1.67 mmol/l*d (P = .001). SD was significantly higher for AGT (1.12 +/- 0.37 vs. 0.85 +/- 0.32 mmol/l, P = .01) and MAGE 2.26 +/- 0.84 vs. 1.60 +/- 0.69 mmol/l, P = .005). In this comparative analysis NGT and AGT well matched for age, BMI, and comorbidities, CGM revealed significant differences in daytime AiG, pp glucose excursion and postprandial peaks. SD and MAGE was significantly higher for subjects with AGT. I Impaired glucose homeostasis a better characterizes degree of AGTe than HbA1c and 75 g OGTT.},\n bibtype = {article},\n author = {Hanefeld, M and Sulk, S and Helbig, M and Thomas, A and Kohler, C},\n journal = {J Diabetes Sci Technol}\n}","author_short":["Hanefeld, M.","Sulk, S.","Helbig, M.","Thomas, A.","Kohler, C."],"urls":{"Paper":"http://bibbase.org/service/mendeley/9119439d-54eb-3aeb-9ae6-8bf806ce7a35/file/69792e6a-3264-0e8d-4364-488ada68378a/2014-Differences_in_Glycemic_Variability_Between_Normoglycemic_and_Prediabetic_Subjects.pdf.pdf"},"bibbaseid":"hanefeld-sulk-helbig-thomas-kohler-differencesinglycemicvariabilitybetweennormoglycemicandprediabeticsubjects-2014","role":"author","keyword":["cgms","continuous glucose monitoring","glucose homeostasis","glucose measurement systems","glycemic variability","hba1c","it became possible to","normal glucose tolerance","prediabetes","reliable and comfortable continuous","with the introduction of"],"downloads":0},"search_terms":["differences","glycemic","variability","between","normoglycemic","prediabetic","subjects","hanefeld","sulk","helbig","thomas","kohler"],"keywords":["cgms","continuous glucose monitoring","glucose homeostasis","glucose measurement systems","glycemic variability","hba1c","it became possible to","normal glucose tolerance","prediabetes","reliable and comfortable continuous","with the introduction of"],"authorIDs":[]}