Synthesizing Clinical Evidence for Economic Evaluation. Hawkins, N. In Encyclopedia of Health Economics, pages 382–385. Elsevier, San Diego, January, 2014. Paper doi abstract bibtex A key aspect of economic evaluation is the estimation of clinical parameters, in particular relating to treatment effects. Network meta-analysis is an extension of pairwise metaanalysis that provides estimates of the relative effectiveness of two or more treatments. These are derived from a statistical analysis of a connected network of clinical trial comparisons. Estimates are obtained that correspond to a consistency constraint on the treatment effect scale used for the analysis (δAB=δAC−δBC), where δAB is the indirect estimate of the effect of treatment A compared with treatment B and δAC and δBB represent the direct estimates of the effects of A versus C and B versus C, respectively, and best fit the treatment effect estimates from individual trials.
@incollection{hawkins_synthesizing_2014-1,
address = {San Diego},
title = {Synthesizing {Clinical} {Evidence} for {Economic} {Evaluation}},
isbn = {978-0-12-375679-4},
url = {http://www.sciencedirect.com/science/article/pii/B9780123756787014048},
abstract = {A key aspect of economic evaluation is the estimation of clinical parameters, in particular relating to treatment effects. Network meta-analysis is an extension of pairwise metaanalysis that provides estimates of the relative effectiveness of two or more treatments. These are derived from a statistical analysis of a connected network of clinical trial comparisons. Estimates are obtained that correspond to a consistency constraint on the treatment effect scale used for the analysis (δAB=δAC−δBC), where δAB is the indirect estimate of the effect of treatment A compared with treatment B and δAC and δBB represent the direct estimates of the effects of A versus C and B versus C, respectively, and best fit the treatment effect estimates from individual trials.},
urldate = {2019-08-06},
booktitle = {Encyclopedia of {Health} {Economics}},
publisher = {Elsevier},
author = {Hawkins, N.},
editor = {Culyer, Anthony J.},
month = jan,
year = {2014},
doi = {10.1016/B978-0-12-375678-7.01404-8},
keywords = {Evidence synthesis, Indirect comparison, Mixed treatment comparison, Network meta-analysis},
pages = {382--385},
file = {ScienceDirect Snapshot:/Users/neil.hawkins/Zotero/storage/G9C4V46F/B9780123756787014048.html:text/html},
}
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